Patents by Inventor Mirella Meyer-Ficca

Mirella Meyer-Ficca has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TRANSIENT IMMORTALIZATION
    Publication number: 20140186311
    Abstract: The invention relates to a method for transiently immortalizing cells according to which immortalization proteins are introduced into the cells from outside. The invention also relates to a method for producing cells according to which organ-related cells are transiently immortalized by the exogenous supply of immortalization proteins and are remortalized after their expansion. The invention further relates to the cells produced according to the inventive method, to the use of said cells for producing a transplant and to the immortalization proteins used in the method.
    Type: Application
    Filed: January 21, 2014
    Publication date: July 3, 2014
    Applicant: HEART BIOSYSTEMS GMBH
    Inventors: Jan-Heiner Kupper, Ralph Meyer, Mirella Meyer-Ficca, Anne Kuhn
  • TRANSIENT IMMORTALIZATION
    Publication number: 20130035287
    Abstract: The invention relates to a method for transiently immortalizing cells according to which immortalization proteins are introduced into the cells from outside. The invention also relates to a method for producing cells according to which organ-related cells are transiently immortalized by the exogenous supply of immortalization proteins and are remortalized after their expansion. The invention further relates to the cells produced according to the inventive method, to the use of said cells for producing a transplant and to the immortalization proteins used in the method.
    Type: Application
    Filed: June 22, 2012
    Publication date: February 7, 2013
    Applicant: HEART BIOSYSTEMS GMBH
    Inventors: Jan-Heiner Kupper, Ralph Meyer, Mirella Meyer-Ficca, Anne Kuhn
  • Tumor-Specific Vector for Gene Therapy
    Publication number: 20080221058
    Abstract: The invention relates to a vector for the gene therapeutic treatment of tumors, especially in connection with radiotherapy. Said vector is provided with a therapeutic gene in the DNA sequence thereof. The gene is controlled by the promoter for the catalytic subunit of the telomerase or by the promoter for cyclin A.
    Type: Application
    Filed: February 13, 2008
    Publication date: September 11, 2008
    Inventors: Jan-Heinerr Kupper, Ralph Meyer, Mirella Meyer-Ficca, Reinhard Kandolf
  • Tumor-specific vector for gene therapy
    Patent number: 7351697
    Abstract: The invention relates to a vector for the gene therapeutic treatment of tumors, especially in connection with radiotherapy. Said vector is provided with a therapeutic gene in the DNA sequence thereof. The gene is controlled by the promoter for the catalytic subunit of the telomerase or by the promoter for cyclin A.
    Type: Grant
    Filed: July 21, 2005
    Date of Patent: April 1, 2008
    Inventors: Jan-Heinerr Küpper, Ralph Meyer, Mirella Meyer-Ficca, Reinhard Kandolf
  • Transient immortalization
    Publication number: 20070237754
    Abstract: The invention relates to a method for transiently immortalizing cells according to which immortalization proteins are introduced into the cells from outside. The invention also relates to a method for producing cells according to which organ-related cells are transiently immortalized by the exogenous supply of immortalization proteins and are remortalized after their expansion. The invention further relates to the cells produced according to the inventive method, to the use of said cells for producing a transplant and to the immortalization proteins used in the method.
    Type: Application
    Filed: May 21, 2007
    Publication date: October 11, 2007
    Inventors: Jan-Heiner Kupper, Ralph Meyer, Mirella Meyer-Ficca, Anne Kuhn
  • Tumor-specific vector for gene therapy
    Publication number: 20050281787
    Abstract: The invention relates to a vector for the gene therapeutic treatment of tumors, especially in connection with radiotherapy. Said vector is provided with a therapeutic gene in the DNA sequence thereof. The gene is controlled by the promoter for the catalytic subunit of the telomerase or by the promoter for cyclin A.
    Type: Application
    Filed: July 21, 2005
    Publication date: December 22, 2005
    Inventors: Jan-Heinerr Kupper, Ralph Meyer, Mirella Meyer-Ficca, Reinhard Kandolf
  • Transient immortalization
    Publication number: 20050244969
    Abstract: The invention relates to a method for transiently immortalizing cells in which immortalizing proteins are introduced into the cells from the exterior, and to a method for obtaining cells in which organ-related cells are transiently immortalized by supplying immortalizing proteins externally and are remortalized after expansion. The invention furthermore relates to cells which are prepared by these methods, to the use of the cells for preparing a transplant and to immortalizing proteins which are to be used in the methods.
    Type: Application
    Filed: October 7, 2002
    Publication date: November 3, 2005
    Inventors: Jan-Heiner Kupper, Ralph Meyer, Mirella Meyer-Ficca, Anne Kuhn
  • Tumour-specific vector for gene therapy
    Patent number: 6936595
    Abstract: The invention relates to a vector for the gene therapeutic treatment of tumours, especially in connection with radiotherapy. Said vector is provided with a therapeutic gene in the DNA sequence thereof. The gene is controlled by the promoter for the catalytic subunit of the telomerase or by the promoter for cyclin A.
    Type: Grant
    Filed: April 2, 2002
    Date of Patent: August 30, 2005
    Assignee: Heart BioSystems, GmbH
    Inventors: Jan-Heiner Küpper, Ralph Meyer, Mirella Meyer-Ficca, Reinhard Kandolf
  • Tumour-specific vector for gene therapy
    Publication number: 20030044385
    Abstract: The invention relates to a vector for the gene therapeutic treatment of tumours, especially in connection with radiotherapy. Said vector is provided with a therapeutic gene in the DNA sequence thereof. The gene is controlled by the promoter for the catalytic subunit of the telomerase or by the promoter for cyclin A.
    Type: Application
    Filed: April 2, 2002
    Publication date: March 6, 2003
    Inventors: Jan-Heiner Kupper, Ralph Meyer, Mirella Meyer-Ficca, Reinhard Kandolf