Abstract: A method and an apparatus for effecting freeze-drying specimens containing solvents or condensing solvents having a shallow pan treatment chamber with little or no obstructions, holes or orifices. The treatment is effected by cooling the base of the chamber by using coolant-containing coils mounted beneath the base of the chamber. The direct thermal conduction of heat through the base of the chamber provides a more effective method of both cooling specimens and condensing solvents, typically water. A source of vacuum is provided to the chamber by a conduit located in the cover, sidewalls or base of the chamber. The method and apparatus may employ a moveable specimen holder positioned in the chamber. The moveable specimen holder may be mounted on a perforated tube which slidably engages a conduit in the base of the chamber. The perforated tube may a conduit to the source of vacuum.