Patents by Inventor Miriam Grgic

Miriam Grgic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fusion moieties and microbial hosts for protein production
    Patent number: 11560582
    Abstract: The present invention relates to fusion proteins comprising (i) a fusion moiety based on SEQ ID NO:1 and (ii) a protein. Also provided are nucleic acids encoding such fusion proteins and compositions comprising such fusion proteins. The invention also provides a method for increasing the expression level of a protein in a host cell or increasing the level of secretion of a protein from a host cell, said methods employing a fusion moiety in accordance with the invention. The invention further provides a method of producing a protein, said method comprising culturing an Aliivibrio wodanis host cell comprising a heterologous nucleic acid molecule encoding a protein under conditions suitable for the expression of the encoded protein. Certain deposited strains of Aliivibrio wodanis are also provided.
    Type: Grant
    Filed: June 19, 2019
    Date of Patent: January 24, 2023
    Assignee: UNIVERSITETET I TROMSØ—NORGES ARKTISKE UNIVERSITET
    Inventors: Peik Haugen, Miriam Grgic, Jenny Johansson Söderberg
  • FUSION MOIETIES AND MICROBIAL HOSTS FOR PROTEIN PRODUCTION
    Publication number: 20210130865
    Abstract: The present invention relates to fusion proteins comprising (i) a fusion moiety based on SEQ ID NO:1 and (ii) a protein. Also provided are nucleic acids encoding such fusion proteins and compositions comprising such fusion proteins. The invention also provides a method for increasing the expression level of a protein in a host cell or increasing the level of secretion of a protein from a host cell, said methods employing a fusion moiety in accordance with the invention. The invention further provides a method of producing a protein, said method comprising culturing an Aliivibrio wodanis host cell comprising a heterologous nucleic acid molecule encoding a protein under conditions suitable for the expression of the encoded protein. Certain deposited strains of Aliivibrio wodanis are also provided.
    Type: Application
    Filed: June 19, 2019
    Publication date: May 6, 2021
    Inventors: Peik Haugen, Miriam Grgic, Jenny Johannsson Sóderberg