Patents by Inventor Miriam Y. Mangelus

Miriam Y. Mangelus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODIES SPECIFIC TO PRO-ANGIOGENIC ISOFORMS OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF)
    Publication number: 20100272733
    Abstract: The present invention provides antibodies, as well as molecules having at least the antigen-binding portion of an antibody, against agonist pro-angiogenic, pro-permeability, vasodilatory isoforms of VEGF. Disclosed antibodies and antibody fragments are characterized by being capable of binding to and neutralizing pro-angiogenic forms of VEGF while not effecting isoforms of VEGF which are anti angiogenic. Methods of production and use in therapy and diagnosis, of such antibodies and antibody fragments are also provided.
    Type: Application
    Filed: October 26, 2008
    Publication date: October 28, 2010
    Applicants: PhiloGene, Inc., University of Bristol
    Inventors: David O. Bates, Steven J. Harper, Miriam Y. Mangelus, Menachem Ze'evi