Patents by Inventor Mirian Akemi Furuie Hayashi

Mirian Akemi Furuie Hayashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods, kits and compositions comprising crotamine
    Patent number: 8278265
    Abstract: The present invention refers to uses of crotamine and compositions containing it, based on its characteristic of interaction with genetic material. Under submicromolar quantities, the polypeptide is no longer toxic, presenting the characteristics properties of cell penetration, transport of molecules to the surface, cytoplasm or cell nucleus and particularly, selective cell penetration. The invention also refers to compositions comprising a pharmaceutically effective concentration of crotamine and its use for the treatment of diseases and dysfunctions, based on its characteristics of interaction with genetic material, such as DNA and RNA, and cell selectivity.
    Type: Grant
    Filed: September 18, 2007
    Date of Patent: October 2, 2012
    Assignee: Fundacao de Amparo a Pesquisa do Estado de Sao Paulo—FAPESP
    Inventors: Tetsuo Yamane, Irina Kerkis, Alexandre Kerkis, Gandhi Rádis Baptista, Mirian Akemi Furuie Hayashi, Katsuhiro Konno, Alvaro Rossan B. P. Da Silva, Lygia da Veiga Pereira, Eduardo Brandt De Oliveira
  • Methods, kits and compositions comprising crotamine
    Publication number: 20080181849
    Abstract: The present invention refers to uses of crotamine and compositions containing it, based on its characteristic of interaction with genetic material. Under submicromolar quantities, the polypeptide is no longer toxic, presenting the characteristics properties of cell penetration, transport of molecules to the surface, cytoplasm or cell nucleus and particularly, selective cell penetration. The invention also refers to compositions comprising a pharmaceutically effective concentration of crotamine and its use for the treatment of diseases and dysfunctions, based on its characteristics of interaction with genetic material, such as DNA and RNA, and cell selectivity.
    Type: Application
    Filed: September 18, 2007
    Publication date: July 31, 2008
    Inventors: Tetsuo Yamane, Irina Kerkis, Alexandre Kerkis, Gandhi Radis Baptista, Mirian Akemi Furuie Hayashi, Katsuhiro Konno, Alvaro Rossan B.P. Da Silva, Lygia da Veiga Pereira, Eduardo Brandt De Oliveira