Patents by Inventor Mirian Gillissen

Mirian Gillissen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OSTEOIMPLANT COMPRISING AN INSOLUBLE FIBROUS POLYMER
    Publication number: 20200289711
    Abstract: Methods for making an osteoimplant are provided. In one embodiment the method includes applying a mechanical force to an aqueous slurry of insoluble collagen fibers to entangle the insoluble collagen fibers so as to form a semi-solid mass of entangled insoluble collagen fibers; and lyophilizing the semi-solid mass of entangled collagen fibers to form the osteoimplant. An osteoimplant containing entangled insoluble collagen fibers is also provided.
    Type: Application
    Filed: May 29, 2020
    Publication date: September 17, 2020
    Inventors: Scott M. Vickers, Jeffrey L. Scifert, Mirian Gillissen, Didier Billy
  • Osteoimplant comprising an insoluble fibrous polymer
    Patent number: 10709814
    Abstract: Methods for making an osteoimplant are provided. In one embodiment the method includes applying a mechanical force to an aqueous slurry of insoluble collagen fibers to entangle the insoluble collagen fibers so as to form a semi-solid mass of entangled insoluble collagen fibers; and lyophilizing the semi-solid mass of entangled collagen fibers to form the osteoimplant. An osteoimplant containing entangled insoluble collagen fibers is also provided.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: July 14, 2020
    Assignee: Warsaw Orthopedic, Inc.
    Inventors: Scott M Vickers, Jeffrey L Scifert, Mirian Gillissen, Didier Billy
  • OSTEOIMPLANT COMPRISING AN INSOLUBLE FIBROUS POLYMER
    Publication number: 20170304502
    Abstract: Methods for making an osteoimplant are provided. In one embodiment the method includes applying a mechanical force to an aqueous slurry of insoluble collagen fibers to entangle the insoluble collagen fibers so as to form a semi-solid mass of entangled insoluble collagen fibers; and lyophilizing the semi-solid mass of entangled collagen fibers to form the osteoimplant. An osteoimplant containing entangled insoluble collagen fibers is also provided.
    Type: Application
    Filed: April 22, 2016
    Publication date: October 26, 2017
    Inventors: Scott M. Vickers, Jeffrey L. Scifert, Mirian Gillissen, Didier Billy
  • Malleable multi-component implants and materials therefor
    Patent number: 9730982
    Abstract: Described are implantable, malleable medical materials comprising mineral particles, insoluble collagen fibers, and a gel-forming polysaccharide component and/or another added gel-former. The malleable medical materials can be used treat bone or other tissue defects in patients, including in conjunction with biologically active factors such as osteogenic proteins. Also described are methods and materials that can be used to prepare the malleable medical materials.
    Type: Grant
    Filed: September 22, 2014
    Date of Patent: August 15, 2017
    Assignee: Warsaw Orthopedic, Inc.
    Inventors: William F. McKay, Jeffrey L. Scifert, Kathy Remsen, Didier Billy, Mirian Gillissen, Scott M. Vickers
  • MALLEABLE MULTI-COMPONENT IMPLANTS AND MATERIALS THEREFOR
    Publication number: 20150011472
    Abstract: Described are implantable, malleable medical materials comprising mineral particles, insoluble collagen fibers, and a gel-forming polysaccharide component and/or another added gel-former. The malleable medical materials can be used treat bone or other tissue defects in patients, including in conjunction with biologically active factors such as osteogenic proteins. Also described are methods and materials that can be used to prepare the malleable medical materials.
    Type: Application
    Filed: September 22, 2014
    Publication date: January 8, 2015
    Inventors: William F. McKay, Jeffrey L. Scifert, Kathy Remsen, Didier Billy, Mirian Gillissen, Scott M. Vickers
  • Malleable multi-component implants and materials therefor
    Patent number: 8840913
    Abstract: Described are implantable, malleable medical materials comprising mineral particles, insoluble collagen fibers, and a gel-forming polysaccharide component and/or another added gel-former. The malleable medical materials can be used treat bone or other tissue defects in patients, including in conjunction with biologically active factors such as osteogenic proteins. Also described are methods and materials that can be used to prepare the malleable medical materials.
    Type: Grant
    Filed: March 27, 2008
    Date of Patent: September 23, 2014
    Assignee: Warsaw Orthopedic, Inc.
    Inventors: William F. McKay, Jeffrey L. Scifert, Kathy L. Remsen, Didier Billy, Mirian Gillissen, Scott M. Vickers
  • Bioactive delivery matrix compositions and methods
    Publication number: 20070087059
    Abstract: Bioactive delivery matrix compositions and methods of making and using such compositions.
    Type: Application
    Filed: October 17, 2005
    Publication date: April 19, 2007
    Inventors: Frank Everaerts, Marc Hendriks, Mirian Gillissen
  • Methods of preparing crosslinked materials and bioprosthetic devices
    Patent number: 7053051
    Abstract: Methods for making crosslinked material, such as collagen-based material, and bioprosthetic devices. The crosslinked material includes hydroxyl groups, carboxyl groups, and amine groups prior to crosslinking. The methods include removing at least a portion of the zero-length ester crosslinks in a crosslinked material and/or blocking at least a portion of the amine groups that are reactive with carboxyl groups and form zero-length crosslinks.
    Type: Grant
    Filed: October 27, 2004
    Date of Patent: May 30, 2006
    Assignee: Medtronic, Inc.
    Inventors: Marc Hendriks, Frank Everaerts, Mirian Gillissen, Michel Verhoeven, Mark W. Torrianni
  • Therapeutic blood vessel treatment
    Publication number: 20060004441
    Abstract: A method and device for the treatment of an aneurysm are provided. Different therapeutic agents are delivered to the aneurysmal site by a delivery vehicle in a localized, time-release regimen, to treat and reduce the severity of the aneurysm. The delivery vehicle is provided in conjunction with the placement of an excluding device, such as a stent graft.
    Type: Application
    Filed: August 3, 2004
    Publication date: January 5, 2006
    Applicant: Medtronic Vascular, Inc.
    Inventors: Edze Tijsma, Mirian Gillissen, Brian Kwitkin
  • Methods of preparing crosslinked materials and bioprosthetic devices
    Publication number: 20050136510
    Abstract: Methods for making crosslinked material, such as collagen-based material, and bioprosthetic devices. The crosslinked material includes hydroxyl groups, carboxyl groups, and amine groups prior to crosslinking. The methods include removing at least a portion of the zero-length ester crosslinks in a crosslinked material and/or blocking at least a portion of the amine groups that are reactive with carboxyl groups and form zero-length crosslinks.
    Type: Application
    Filed: October 27, 2004
    Publication date: June 23, 2005
    Inventors: Marc Hendriks, Frank Everaerts, Mirian Gillissen, Michel Verhoeven, Mark Torrianni
  • Method for attachment of biomolecules to surfaces of medical devices
    Patent number: 6024918
    Abstract: A method for making a medical device having a biomolecule immobilized on a substrate surface is provided. The method includes coating the substrate surface with an amino-functional polysiloxane; and contacting the amino-functional polysiloxane coated surface with a biomolecule under conditions effective to immobilize the biomolecule.
    Type: Grant
    Filed: March 13, 1998
    Date of Patent: February 15, 2000
    Assignee: Medtronic, Inc.
    Inventors: Marc Hendriks, Michel Verhoeven, Patrick Cahalan, Linda Cahalan, Edouard Koulik, Mirian Gillissen