Patents by Inventor Mirja ROTINEN

Mirja ROTINEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for treating cancer
    Patent number: 11529338
    Abstract: Provided herein are compositions and methods for treating, inhibiting and/or reducing the severity of neuroblastoma, small cell lung cancer (SCLC), large cell neuroendocrine cancer (LCNEC), large-cell carcinoma (LCC), squamous cell carcinoma (SqCC), and/or adenocarcinoma (AC) in subjects in need thereof. The methods include providing an agent that inhibits expression or activity of ONECUT2 and administering a therapeutically effective amount of the agent so as to treat, inhibit and/or reduce the severity of neuroblastoma, small cell lung cancer (SCLC), large cell neuroendocrine cancer (LCNEC), large-cell carcinoma (LCC), squamous cell carcinoma (SqCC), and/or adenocarcinoma (AC) in the subject.
    Type: Grant
    Filed: August 22, 2018
    Date of Patent: December 20, 2022
    Assignee: Cedars-Sinai Medical Center
    Inventors: Michael Freeman, Mirja Rotinen, Ramachandran Murali, Sungyong You
  • COMPOSITIONS AND METHODS FOR TREATING CANCER
    Publication number: 20210163403
    Abstract: Provided herein are compositions and methods for treating, inhibiting and/or reducing the severity of cancer in subjects in need thereof. The methods include providing an agent that inhibits expression or activity of ONECUT2 and administering a therapeutically effective amount of the agent so as to treat, inhibit and/or reduce the severity of cancer in the subject.
    Type: Application
    Filed: January 8, 2021
    Publication date: June 3, 2021
    Applicant: Cedars-Sinai Medical Center
    Inventors: Michael FREEMAN, Mirja ROTINEN, Ramachandran MURALI, Sungyong YOU
  • Compositions and methods for treating cancer
    Patent number: 10927070
    Abstract: Provided herein are compositions and methods for treating, inhibiting and/or reducing the severity of cancer in subjects in need thereof. The methods include providing an agent that inhibits expression or activity of ONECUT2 and administering a therapeutically effective amount of the agent so as to treat, inhibit and/or reduce the severity of cancer in the subject.
    Type: Grant
    Filed: May 26, 2017
    Date of Patent: February 23, 2021
    Assignee: Cedars-Sinai Medical Center
    Inventors: Michael Freeman, Mirja Rotinen, Ramachandran Murali, Sungyong You
  • COMPOSITIONS AND METHODS FOR TREATING CANCER
    Publication number: 20200188373
    Abstract: Provided herein are compositions and methods for treating, inhibiting and/or reducing the severity of neuroblastoma, small cell lung cancer (SCLC), large cell neuroendocrine cancer (LCNEC), large-cell carcinoma (LCC), squamous cell carcinoma (SqCC), and/or adenocarcinoma (AC) in subjects in need thereof. The methods include providing an agent that inhibits expression or activity of ONECUT2 and administering a therapeutically effective amount of the agent so as to treat, inhibit and/or reduce the severity of neuroblastoma, small cell lung cancer (SCLC), large cell neuroendocrine cancer (LCNEC), large-cell carcinoma (LCC), squamous cell carcinoma (SqCC), and/or adenocarcinoma (AC) in the subject.
    Type: Application
    Filed: August 22, 2018
    Publication date: June 18, 2020
    Applicant: Cedars-Sinai Medical Center
    Inventors: Michael FREEMAN, Mirja ROTINEN, Ramachandran MURALI, Sungyong YOU
  • COMPOSITIONS AND METHODS FOR TREATING CANCER
    Publication number: 20190194124
    Abstract: Provided herein are compositions and methods for treating, inhibiting and/or reducing the severity of cancer in subjects in need thereof The methods include providing an agent that inhibits expression or activity of ONECUT2 and administering a therapeutically effective amount of the agent so as to treat, inhibit and/or reduce the severity of cancer in the subject.
    Type: Application
    Filed: May 26, 2017
    Publication date: June 27, 2019
    Applicant: Cedars-Sinai Medical Center
    Inventors: Michael FREEMAN, Mirja ROTINEN, Ramachandran MURALI, Sungyong YOU