Patents by Inventor Mirjana Krajacic

Mirjana Krajacic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted 9A-N-[N'-(Benzenesulfonyl)Carbamoyl-Y-Aminopropyl] and 9A-N-[N'(B-Cyanoethyl)-N'-(Benzenesulfonyl)Carbamoyl-Y-Aminopropyl]Derivatives of 9-Deoxo-9-Dihydro-9A-Aza-9A-Homoerithomycin A
    Publication number: 20070270356
    Abstract: The invention relates to substituted 9a-N—[N?-(benzenesulfonyl)carbamoyl-?-aminopropyl] and 9a-N—[N?-(?-cyanoethyl)-N?-(benzenesulfonyl)carbamoyl-?-aminopropyl] derivatives of 9-deoxo-9-dihydro-9a-aza-9a-homoerithromycin A and 5-( )-desosaminyl-9-deoxo-9-dihydro-9a-aza-9a-homoerithronolide A, novel semisynthetic macrolide antibiotics of the azalide series, of the formula (I) wherein R represents H or cladinosyl moiety, R1 represents H or ?-cyanoethyl group an R2 represents II or fluoro, chloro and methyl group, and pharmaceutically acceptable salts thereof with inorganic or organic acids, to the process for the preparation of pharmaceutical compositions as well as to the use their compositions for sterilization rooms and medical instruments as well as for protection of wall and wooden coatings.
    Type: Application
    Filed: November 10, 2003
    Publication date: November 22, 2007
    Applicant: GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O.
    Inventors: Nedjeljko Kujundzic, Mirjana Krajacic, Karmen Brajsa
  • Novel semisynthetic macrolide antibiotics of the azalide series
    Publication number: 20060252709
    Abstract: The invention relates to N?-substituted 9a-N-(N?-carbamoyl-?-aminopropyl), 9a-N-(N?-thiocarbamoyl-?-amino-propyl), 9a-N-[N?-((?-cyanoethyl)-N?-carbamoyl-?-aminopropyl] and 9a-N-[N?-((?-cyanoethyl)-N?-thiocarbamoyl-?-aminopropyl] derivatives of 9-deoxo-9-dihydro-9a-aza-9a-homoerithromycin A and 5-0-desosaminyl-9-deoxo-9-dihydro-9a-aza-9a-homoerithronolide A, novel semisynthetic macrolide antibiotics of the azalide series, of the general formula 1, wherein R represents H or cladinosyl moiety, R1 represents H or (?-cyanoethyl moiety, R2 represents isopropyl, 1-naphtyl, 2-naphtyl, benzyl, 2-(trifluommethyl)phenyl, 3-phenylpropyl, ?-phenylethyl, ethoxycarbonylmethyl, 1-(1-naphtyl)ethyl, 3,4,5-trimethoxyphenyl and 2,4-dichlorophenyl group, and X represents 0 and S, and their acceptable addition salts thereof with inorganic or organic acids, to the process for preparation of their pharmaceutical compositions as well as the use their compositions in the treatment of bacterial infections.
    Type: Application
    Filed: December 10, 2003
    Publication date: November 9, 2006
    Applicant: Pliva-Istrazivacki Institut d.o.o.
    Inventors: Nedjeljko Kujundzic, Mirjana Krajacic, Karmen Brajsa
  • Substituted 9a-n-[n'-(benzenesulfonyl)carbamoyl-aminopropyl]and 9a-n-[n'-(b-cya-neothyl) -n-[n'-(benzenesulfonyl)carbamoyl-y-aminopropyl]derivatives of 9-deoxo-9-dihydro-9a-aza- 9a-homoerithromycin a and 5-0-aza-homoerithronolide a
    Publication number: 20060084795
    Abstract: The invention relates to substituted 9a-N-{N?-[4-(sulfonyl)phenyl]carbamoyl} derivatives of 9-deoxo-9-dihydro-9a-aza-9a-homoerithromycin A and 5-0-desosaminyl-9-deoxo-9-di-hydro-9a-aza-9a-homoerithronolide A, novel semisynthetic macrolide antibiotics of the azalide series general formula (1), wherein R represents H or cladinosyl moiety and R1 represents chloro, amino, phenylamino, 2-pyridylamino, 3,4-dimethyl-4-isoxalylamino and 5-methyl-3-isoxazolylamino group, and pharmaceutically acceptable addition salts thereof with inorganic or organic acids.
    Type: Application
    Filed: November 10, 2003
    Publication date: April 20, 2006
    Applicant: Pliva-Istrazivacki Institut d.o.o.
    Inventors: Nedjelijko Kujundzic, Mirjana Krajacic, Karmen Brajsa