Patents by Inventor Mirna Koscec

Mirna Koscec has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9624528
    Abstract: A method of determining the thrombogenicity of an implantable medical device is disclosed. The implanted device is exposed in vitro to platelet rich plasma, the activity of an indicator is assayed, and the thrombogenicity is determined.
    Type: Grant
    Filed: October 20, 2015
    Date of Patent: April 18, 2017
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Mirna Koscec, Eugen Koren
  • Publication number: 20160076077
    Abstract: A method of determining the thrombogenicity of an implantable medical device is disclosed. The implanted device is exposed in vitro to platelet rich plasma, the activity of an indicator is assayed, and the thrombogenicity is determined.
    Type: Application
    Filed: October 20, 2015
    Publication date: March 17, 2016
    Inventors: Mirna Koscec, Eugen Koren
  • Patent number: 9193987
    Abstract: A method of determining the thrombogenicity of an implantable medical device is disclosed. The implanted device is exposed in vitro to platelet rich plasma, the activity of an indicator is assayed, and the thrombogenicity is determined.
    Type: Grant
    Filed: April 18, 2014
    Date of Patent: November 24, 2015
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Mirna Koscec, Eugen Koren
  • Publication number: 20150299759
    Abstract: A method of determining the thrombogenicity of an implantable medical device is disclosed. The implanted device is exposed in vitro to platelet rich plasma, the activity of an indicator is assayed, and the thrombogenicity is determined.
    Type: Application
    Filed: April 18, 2014
    Publication date: October 22, 2015
    Inventors: Mirna Koscec, Eugen Koren
  • Patent number: 7098036
    Abstract: Compositions and methods using antibodies which are immunoreactive with specific apolipoproteins to determine the concentrations of lipoproteins such as HDL and LDL, and/or apolipoproteins in human blood, serum or plasma sample, are described. Monoclonal antibodies (MAbs) are described that specifically bind to epitopes present in apolipoproteins and lipoproteins, enabling rapid and reliable determinations of levels of specific blood lipoprotein and/or apolipoprotein levels, including Apo B-100, Apo A-I, Apo A-II, Apo C-III, and Apo E, and thereby determination of relative ratios of HDL and LDL and LpaI and LpaII. In a preferred embodiment, the compositions are strips of a solid phase material coated with one or more of the antibodies and are referred to herein as “dipsticks”. The dipsticks specifically bind a lipoprotein or apolipoprotein when dipped into a protein sample.
    Type: Grant
    Filed: November 13, 1997
    Date of Patent: August 29, 2006
    Assignee: Okalahoma Medical Research Foundation
    Inventors: Eugen Koren, Mirna Koscec
  • Publication number: 20040053321
    Abstract: Compositions and methods using antibodies which are immunoreactive with specific apolipoproteins to determine the concentrations of lipoproteins such as HDL and LDL, and/or apolipoproteins in human blood, serum or plasma sample, are described. Monoclonal antibodies (MAbs) are described that specifically bind to epitopes present in apolipoproteins and lipoproteins, enabling rapid and reliable determinations of levels of specific blood lipoprotein and/or apolipoprotein levels, including Apo B-100, Apo A-I, Apo A-II, Apo C-III, and Apo E, and thereby determination of relative ratios of HDL and LDL and LpaI and LpaII. In a preferred embodiment, the compositions are strips of a solid phase material coated with one or more of the antibodies and are referred to herein as “dipsticks”. The dipsticks specifically bind a lipoprotein or apolipoprotein when dipped into a protein sample.
    Type: Application
    Filed: December 24, 1996
    Publication date: March 18, 2004
    Applicant: PATREA L PABST HOLLAND AND KNIGHT LLP
    Inventors: EUGEN KOREN, MIRNA KOSCEC
  • Publication number: 20020098597
    Abstract: Compositions and methods using antibodies which are immunoreactive with specific apolipoproteins to determine the concentrations of lipoproteins such as HDL and LDL, and/or apolipoproteins in human blood, serum or plasma sample, are described. Monoclonal antibodies (MAbs) are described that specifically bind to epitopes present in apolipoproteins and lipoproteins, enabling rapid and reliable determinations of levels of specific blood lipoprotein and/or apolipoprotein levels, including Apo B-100, Apo A-I, Apo A-II, Apo C-III, and Apo E, and thereby determination of relative ratios of HDL and LDL and LpaI and LpaII. In a preferred embodiment, the compositions are strips of a solid phase material coated with one or more of the antibodies and are referred to herein as “dipsticks”. The dipsticks specifically bind a lipoprotein or apolipoprotein when dipped into a protein sample.
    Type: Application
    Filed: November 13, 1997
    Publication date: July 25, 2002
    Inventors: EUGEN KOREN, MIRNA KOSCEC
  • Patent number: 6107045
    Abstract: Compositions and methods using antibodies which are immunoreactive with specific apolipoproteins to determine the concentrations of lipoproteins such as HDL and LDL, and/or apolipoproteins in human blood, serum or plasma sample, are described. Monoclonal antibodies (MAbs) are described that specifically bind to epitopes present in apolipoproteins and lipoproteins, enabling rapid and reliable determinations of levels of specific blood lipoprotein and/or apolipoprotein levels, including Apo B-100, Apo A-I, Apo A-II, Apo C-III, and Apo E, and thereby determination of relative ratios of HDL and LDL and LpaI and LpaII. In a preferred embodiment, the compositions are strips of a solid phase material coated with one or more of the antibodies and are referred to herein as "dipsticks". The dipsticks specifically bind a lipoprotein or apolipoprotein when dipped into a protein sample.
    Type: Grant
    Filed: June 30, 1994
    Date of Patent: August 22, 2000
    Assignee: Oklahoma Medical Research Foundation
    Inventors: Eugen Koren, Mirna Koscec