Patents by Inventor Miron Krimsky

Miron Krimsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150057244
    Abstract: This invention provides a method of preventing or treating a dermatologic condition including, inter alia, psoriasis, contact dermatitis, and atopic dermatitis, in a subject, the method includes the step of administering to said subject a compound comprising a lipid or phospholipid moiety bound to a physiologically acceptable monomer, dimer, oligomer, or polymer, and/or a pharmaceutically acceptable salt or a pharmaceutical product thereof, in an amount effective to treat the subject suffering from a dermatologic condition.
    Type: Application
    Filed: November 5, 2014
    Publication date: February 26, 2015
    Inventors: SAUL YEDGAR, Miron Krimsky, Arie Ingber
  • Patent number: 8916539
    Abstract: This invention provides a method of preventing or treating a dermatologic condition including, inter alia, psoriasis, contact dermatitis, and atopic dermatitis, in a subject, the method includes the step of administering to said subject a compound comprising a lipid or phospholipid moiety bound to a physiologically acceptable monomer, dimer, oligomer, or polymer, and/or a pharmaceutically acceptable salt or a pharmaceutical product thereof, in an amount effective to treat the subject suffering from a dermatologic condition.
    Type: Grant
    Filed: September 21, 2006
    Date of Patent: December 23, 2014
    Assignee: Yissum Research Development Company of The Hebrew University of Jerusalem
    Inventors: Saul Yedgar, Miron Krimsky, Arie Ingber
  • Patent number: 8501701
    Abstract: The invention relates to methods of use for compounds in treating, reducing the incidence, reducing the severity or pathogenesis of an intestinal disease or condition in a subject, including, inter alia, inflammatory bowel disease, Crohn's disease, ulcerative colitis, or a combination thereof.
    Type: Grant
    Filed: November 14, 2006
    Date of Patent: August 6, 2013
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Saul Yedgar, Moshe Ligumski, Miron Krimsky
  • Publication number: 20070117779
    Abstract: The invention relates to methods of use for compounds in treating, reducing the incidence, reducing the severity or pathogenesis of an intestinal disease or condition in a subject, including, inter alia, inflammatory bowel disease, Crohn's disease, ulcerative colitis, or a combination thereof.
    Type: Application
    Filed: November 14, 2006
    Publication date: May 24, 2007
    Inventors: Saul Yedgar, Moshe Ligumski, Miron Krimsky
  • Publication number: 20070078107
    Abstract: This invention provides a method of preventing or treating a dermatologic condition including, inter alia, psoriasis, contact dermatitis, and atopic dermatitis, in a subject, the method includes the step of administering to said subject a compound comprising a lipid or phospholipid moiety bound to a physiologically acceptable monomer, dimer, oligomer, or polymer, and/or a pharmaceutically acceptable salt or a pharmaceutical product thereof, in an amount effective to treat the subject suffering from a dermatologic condition.
    Type: Application
    Filed: September 21, 2006
    Publication date: April 5, 2007
    Inventors: Saul Yedgar, Miron Krimsky, Arie Ingber
  • Patent number: 7141552
    Abstract: The invention provides a method for treating a subject suffering from an intestinal disease, including, inter alia, Crohn's disease, ulcerative colitis, immuno-inflammatory intestinal injury, drug-induced enteropathy and ischemia-induced intestinal injury. This invention further provides a pharmaceutical composition for treating a subject suffering from an intestinal disease, including, inter alia, a lipid or phospholipid moiety bonded to a physiologically acceptable monomer, dimer, oligomer, or polymer, and a pharmaceutically acceptable carrier or excipient.
    Type: Grant
    Filed: March 2, 2004
    Date of Patent: November 28, 2006
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Saul Yedgar, Moshe Ligumski, Miron Krimsky
  • Patent number: 7101859
    Abstract: The invention provides novel methods for treating disease based upon the medicinal use of lipids and phospholipids covalently bound to physiologically acceptable monomers or polymers. Phosphatidylethanolamine moieties conjugated to physiologically acceptable monomers and polymers (PE conjugates) manifest an unexpectedly wide range of pharmacological effects, including stabilizing cell membranes; limiting oxidative damage to cell and blood components; limiting cell proliferation, cell extravasation and (tumor) cell migratory behavior; suppressing immune responses; and attenuating physiological reactions to stress, as expressed in elevated chemokine levels.
    Type: Grant
    Filed: July 28, 2003
    Date of Patent: September 5, 2006
    Assignee: Yissum Research Development Company of The Hebrew University of Jerusalem
    Inventors: Saul Yedgar, Miron Krimsky, Grietje Beck, Benito Antonio Yard, Fokko Johannes van der Woude
  • Patent number: 7034006
    Abstract: The invention provides novel methods for treating disease based upon the medicinal use of lipids and phospholipids covalently bound to physiologically acceptable monomers or polymers. Phosphatidylethanolamine moieties conjugated to physiologically acceptable monomers and polymers (PE conjugates) manifest an unexpectedly wide range of pharmacological effects, including stabilizing cell membranes; limiting oxidative damage to cell and blood components; limiting cell proliferation, cell extravasation and (tumor) cell migratory behavior; suppressing immune responses; and attenuating physiological reactions to stress, as expressed in elevated chemokine levels.
    Type: Grant
    Filed: January 10, 2001
    Date of Patent: April 25, 2006
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Saul Yedgar, David Shuseyov, Gershon Golomb, Reuven Reich, Isaac Ginsburg, Abd-al-Roof Higazi, Moshe Ligumski, Miron Krimsky, David Ojcius, Benito Antonio Yard, Fokko Johannes van der Woude, Edit Schnitzer
  • Publication number: 20040229842
    Abstract: The invention provides a method for treating a subject suffering from an intestinal disease, including, inter alia, Crohn's disease, ulcerative colitis, immuno-inflammatory intestinal injury, drug-induced enteropathy and ischemia-induced intestinal injury. This invention further provides a pharmaceutical composition for treating a subject suffering from an intestinal disease, including, inter alia, a lipid or phospholipid moiety bonded to a physiologically acceptable monomer, dimer, oligomer, or polymer, and a pharmaceutically acceptable carrier or excipient.
    Type: Application
    Filed: March 2, 2004
    Publication date: November 18, 2004
    Inventors: Saul Yedgar, Moshe Ligumski, Miron Krimsky
  • Publication number: 20040087492
    Abstract: The invention provides novel methods for treating disease based upon the medicinal use of lipids and phospholipids covalently bound to physiologically acceptable monomers or polymers. Phosphatidylethanolamine moieties conjugated to physiologically acceptable monomers and polymers (PE conjugates) manifest an unexpectedly wide range of pharmacological effects, including stabilizing cell membranes; limiting oxidative damage to cell and blood components; limiting cell proliferation, cell extravasation and (tumor) cell migratory behavior; suppressing immune responses; and attenuating physiological reactions to stress, as expressed in elevated chemokine levels.
    Type: Application
    Filed: July 28, 2003
    Publication date: May 6, 2004
    Inventors: Saul Yedgar, Miron Krimsky, Grietje Beck, Benito Antonio Yard, Fokko Johannes van der Woude
  • Publication number: 20020049183
    Abstract: The invention provides novel methods for treating disease based upon the medicinal use of lipids and phospholipids covalently bound to physiologically acceptable monomers or polymers. Phosphatidylethanolamine moieties conjugated to physiologically acceptable monomers and polymers (PE conjugates) manifest an unexpectedly wide range of pharmacological effects, including stabilizing cell membranes; limiting oxidative damage to cell and blood components; limiting cell proliferation, cell extravasation and (tumor) cell migratory behavior; suppressing immune responses; and attenuating physiological reactions to stress, as expressed in elevated chemokine levels.
    Type: Application
    Filed: January 10, 2001
    Publication date: April 25, 2002
    Inventors: Saul Yedgar, David Shuseyov, Gershon Golomb, Reuven Reich, Isaac Ginsburg, Abd-al-Roof Higazi, Moshe Ligumski, Miron Krimsky, David Ojcius, Benito Antonio Yard, Fokko Johannes van der Woude, Edit Schnitzer