Patents by Inventor Miroslav PALÍK

Miroslav PALÍK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for isolation and purification of naltrexone
    Patent number: 11161853
    Abstract: The invention describes a method for purification of naltrexone base from reaction mixtures concentrated by evaporation and/or from mixtures containing naltrexone in the presence of other organic or inorganic substances by trituration and/or extraction and crystallization from cyclopentyl methyl ether (CPME), optionally from a mixture of cyclopentyl methyl ether and another organic solvent. Naltrexone of high purity is obtained by this method and can be used in a parenteral dosage form.
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: November 2, 2021
    Assignee: SANECA PHARMACEUTICALS A.S.
    Inventors: Miroslav Kavala, Du{hacek over (s)}an Vandák, Miroslav Palík, Ján Ga{hacek over (s)}par, Richard Hercek
  • METHOD FOR ISOLATION AND PURIFICATION OF NALTREXONE
    Publication number: 20200048271
    Abstract: The invention describes a method for purification of naltrexone base from reaction mixtures concentrated by evaporation and/or from mixtures containing naltrexone in the presence of other organic or inorganic substances by trituration and/or extraction and crystallization from cyclopentyl methyl ether (CPME), optionally from a mixture of cyclopentyl methyl ether and another organic solvent. Naltrexone of high purity is obtained by this method and can be used in a parenteral dosage form.
    Type: Application
    Filed: October 6, 2017
    Publication date: February 13, 2020
    Applicant: SANECA PHARMACEUTICALS A.S.
    Inventors: Miroslav KAVALA, Dusan VANDÁK, Miroslav PALÍK, Ján GASPAR, Richard HERCEK