Patents by Inventor Misao Okitsu

Misao Okitsu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Penicillaminamide derivatives
    Patent number: 6239150
    Abstract: Compounds represented by the general formula (I) wherein n represents 1 or 2; R1 represents, for example, a C1-C10 alkyl group which may be substituted with a C3-C10 cycloalkyl group or carboxyl group; R2 represents hydrogen atom, a C1-C10 alkyl group or other; and R3 represents amino group or amidino group, whose example include trans-4-amino-[(S)-N-[(S)-2-propoxycarbonylamino-3-isopropylthio-3-methyl-butanoyl]prolyl]aminomethylcyclohexane. The compounds have potent inhibitory activity against thrombin, and are useful as anticoagulants.
    Type: Grant
    Filed: March 12, 1998
    Date of Patent: May 29, 2001
    Assignee: Mitsubishi Chemical Corporation
    Inventors: Masahiro Oshima, Norimichi Iwase, Naoto Inakoshi, Koichi Sugawara, Misao Okitsu
  • Prolineamide derivatives
    Patent number: 5744487
    Abstract: A prolineamide derivative represented by the formula (I): ##STR1## or a salt or hydrate thereof or a pharmaceutically acceptable salt thereof, which has a protease inhibition activity and is useful as an active ingredient of pharmaceutical compositions is provided.
    Type: Grant
    Filed: January 26, 1995
    Date of Patent: April 28, 1998
    Assignee: Mitsubishi Chemical Corporation
    Inventors: Masahiro Ohshima, Norimichi Iwase, Shigeo Sugiyama, Koichi Sugawara, Misao Okitsu, Yoshikuni Tamao, Yasuhiro Morinaka