Patents by Inventor Misato MATSUI

Misato MATSUI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200048675
    Abstract: A method of producing a substance includes synthesizing a molecule at least by mixing substrates, a synthase, adenosine triphosphate (ATP), a polyphosphate kinase 2, and a polyphosphoric acid mixture. The polyphosphoric acid mixture includes 50% or more of polyphosphoric acid with a degree of polymerization of not less than 15. Adenosine diphosphate (ADP) is generated from the ATP during the synthesis. The synthesis is coupled with an ATP regeneration reaction in which the ATP is regenerated by the polyphosphate kinase 2 from the ADP and the polyphosphoric acid.
    Type: Application
    Filed: October 30, 2019
    Publication date: February 13, 2020
    Applicant: KANEKA CORPORATION
    Inventors: Misato Matsui, Noriyuki Ito, Yoshihiko Yasohara
  • Publication number: 20190249165
    Abstract: A polypeptide includes a mutant sequence of the amino acid sequence of SEQ ID NO: The mutant sequence includes one or more amino acid substitutions in the amino acid sequence of SEQ ID NO: 1 at positions 13, 17, 20, 23, 39, 70, 78, 101, 113, 125, 126, 136, 138, 149, 152, 154, 155, 197, 200, 215, 226, 227, 230, 239, 241, 246, 249, 254, 260, 262, 263, 270, 278, 299, 305, 307, and 310. The mutant sequence may further include one or more amino acid substitutions, additions, insertions, or deletions. The mutant sequence, excluding the substituted residue(s), may have a sequence identity of 80% or more with the amino acid sequence of SEQ ID NO: 1.
    Type: Application
    Filed: April 25, 2019
    Publication date: August 15, 2019
    Applicant: KANEKA CORPORATION
    Inventors: Misato Matsui, Noriyuki Ito, Yoshihiko Yasohara
  • Patent number: 10294461
    Abstract: An object of the present invention is to modify a wild-type enzyme that is less reactive in the presence of an organic solvent to provide altered carbonyl reductases having better reactivity in the presence of the organic solvent than the wild-type enzyme, and/or to provide transformants producing such reductases. The present inventors have found altered carbonyl reductases having better reactivity in the presence of an organic solvent than the wild-type enzyme, from among a mutant enzyme library prepared by randomly mutating the wild-type enzyme gene, thereby arriving at completion of the present invention.
    Type: Grant
    Filed: March 25, 2014
    Date of Patent: May 21, 2019
    Assignee: KANEKA CORPORATION
    Inventors: Misato Matsui, Noriyuki Ito, Shigeru Kawano, Yoshihiko Yasohara
  • Publication number: 20160040138
    Abstract: An object of the present invention is to modify a wild-type enzyme that is less reactive in the presence of an organic solvent to provide altered carbonyl reductases having better reactivity in the presence of the organic solvent than the wild-type enzyme, and/or to provide transformants producing such reductases. The present inventors have found altered carbonyl reductases having better reactivity in the presence of an organic solvent than the wild-type enzyme, from among a mutant enzyme library prepared by randomly mutating the wild-type enzyme gene, thereby arriving at completion of the present invention.
    Type: Application
    Filed: March 25, 2014
    Publication date: February 11, 2016
    Applicant: KANEKA CORPORATION
    Inventors: Misato MATSUI, Noriyuki ITO, Shigeru KAWANO, Yoshihiko YASOHARA