Patents by Inventor Mitch A. Garcia

Mitch A. Garcia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Systems, methods and components for isolating cells from a fluid sample
    Patent number: 10634587
    Abstract: A system for isolating preselected cell types from a fluid sample that includes a plurality of cell types includes a cell-capture fluidic chip, and a chip holder configured to receive the cell-capture fluidic chip and to maintain the cell-capture fluidic chip with a substantially fluid-tight seal while in operation. The chip holder is further configured to release the cell-capture fluidic chip to be removed from the chip holder for further processing. The cell-capture fluidic chip includes a substrate, a laser micro-dissection membrane disposed on the substrate, and a channel-defining layer disposed on the laser micro-dissection membrane. The laser micro-dissection membrane has a surface adapted to capture preselected cell types preferentially over other cell types of the plurality of cell types. The channel-defining layer is removable from the laser micro-dissection membrane for further processing of the cell-capture fluidic chip.
    Type: Grant
    Filed: April 9, 2018
    Date of Patent: April 28, 2020
    Assignee: The Regents of the University of California
    Inventors: Hsian-Rong Tseng, Mitch A. Garcia, Min Song, Libo Zhao, Shuang Hou, Tom Lee
  • SYSTEMS, METHODS AND COMPONENTS FOR ISOLATING CELLS FROM A FLUID SAMPLE
    Publication number: 20180231441
    Abstract: A system for isolating preselected cell types from a fluid sample that includes a plurality of cell types includes a cell-capture fluidic chip, and a chip holder configured to receive the cell-capture fluidic chip and to maintain the cell-capture fluidic chip with a substantially fluid-tight seal while in operation. The chip holder is further configured to release the cell-capture fluidic chip to be removed from the chip holder for further processing. The cell-capture fluidic chip includes a substrate, a laser micro-dissection membrane disposed on the substrate, and a channel-defining layer disposed on the laser micro-dissection membrane. The laser micro-dissection membrane has a surface adapted to capture preselected cell types preferentially over other cell types of the plurality of cell types. The channel-defining layer is removable from the laser micro-dissection membrane for further processing of the cell-capture fluidic chip.
    Type: Application
    Filed: April 9, 2018
    Publication date: August 16, 2018
    Applicant: The Regents of the University of California
    Inventors: Hsian-Rong Tseng, Mitch A. Garcia, Min Song, Libo Zhao, Shuang Hou, Tom Lee
  • SYSTEMS, METHODS AND COMPONENTS FOR ISOLATING CELLS FROM A FLUID SAMPLE
    Publication number: 20150285717
    Abstract: A system for isolating preselected cell types from a fluid sample that includes a plurality of cell types includes a cell-capture fluidic chip, and a chip holder configured to receive the cell-capture fluidic chip and to maintain the cell-capture fluidic chip with a substantially fluid-tight seal while in operation. The chip holder is further configured to release the cell-capture fluidic chip to be removed from the chip holder for further processing. The cell-capture fluidic chip includes a substrate, a laser micro-dissection membrane disposed on the substrate, and a channel-defining layer disposed on the laser micro-dissection membrane. The laser micro-dissection membrane has a surface adapted to capture preselected cell types preferentially over other cell types of the plurality of cell types. The channel-defining layer is removable from the laser micro-dissection membrane for further processing of the cell-capture fluidic chip.
    Type: Application
    Filed: May 29, 2013
    Publication date: October 8, 2015
    Applicants: The Regents of the University of California, CytoLumina Technologies Corp, Inc.
    Inventors: Hsian-Rong Tseng, Mitch A. Garcia, Min Song, Libo Zhao, Shuang Hou, Tom Lee, Daniel Wang, Bo Tao