Abstract: A firearm with safety mechanism in one embodiment includes a barrel supported by a housing, at least one cartridge-receiving chamber in communication with a bore of the barrel, and a rotatable hammer. The safety mechanism includes a biased safety component, which may be a blocking pin in one embodiment, mounted to and rotatable with the hammer. When the firearm is exposed to an abnormal impact force caused by bumping or dropping the firearm, the safety component changes position and interacts with a blocking feature on the hammer pivot pin to stop or delay the motion of the hammer in a manner which prevents discharging the firearm. The blocking feature may be a notch in one embodiment. Rotating the hammer between rearward cocked and forward firing positions alternatingly aligns or misaligns the blocking pin with the notch, respectively.

Abstract: Systems and methods of the various embodiments may provide metal electrodes for electrochemical cells. In various embodiments, the electrodes may comprise iron. Various methods may enable achieving high surface area with low cost for production of metal electrodes, such as iron electrodes.

Abstract: Materials, designs, and methods of fabrication for iron-manganese oxide electrochemical cells are disclosed. In various embodiments, the negative electrode is comprised of pelletized, briquetted, or pressed iron-bearing components, including metallic iron or iron-based compounds (oxides, hydroxides, sulfides, or combinations thereof), collectively called “iron negative electrode.” In various embodiments, the positive electrode is comprised of pelletized, briquetted, or pressed manganese-bearing components, including manganese (IV) oxide (MnO2), manganese (III) oxide (Mn2O3), manganese (III) oxyhydroxide (MnOOH), manganese (II) oxide (MnO), manganese (II) hydroxide (Mn(OH)2), or combinations thereof, collectively called “manganese oxide positive electrode.” In various embodiments, electrolyte is comprised of aqueous alkali metal hydroxide including lithium hydroxide (LiOH), sodium hydroxide (NaOH), potassium hydroxide (KOH), cesium hydroxide (CsOH), or combinations thereof.

Abstract: Systems and methods of the various embodiments may provide device architectures for batteries. In various embodiments, these may be primary or secondary batteries. In various embodiments these devices may be useful for energy storage. Various embodiments may provide a battery including an Oxygen Reduction Reaction (ORR) electrode, an Oxygen Evolution Reaction (OER) electrode, a metal electrode; and an electrolyte separating the ORR electrode and the OER electrode from the metal electrode.

Abstract: A method for applying LED light treatment includes initiating operation of at least one LED of an LED array of an LED module for a predetermined period of time; and during the predetermined period of time, receiving a signal from a light sensor that indicates light reflected from a surface of a patient's wound. During operation, when the signal from the light sensor indicates that an appropriate dose of light is not being irradiated, operation of the at least one LED is adjusted and when the signal from the light sensor indicates the appropriate dose of light is being irradiated, operation of the at least one LED continues until the predetermined period of time has been achieved.

Abstract: Technologies and implementations for using unmanned aerial vehicles in emergency applications.

Abstract: A defibrillation device for administering an electrotherapy, such as a dual-sequential defibrillation (DSD) electrotherapy. The defibrillation device can include a defibrillation therapy module, a physiological parameter module and a control module. The defibrillation therapy module can output one or more energies and the physiological parameter module can receive one or more physiological parameters, including electrocardiogram (ECG) data. The control module can analyze the physiological parameters to determine an indication for the administration of an electrotherapy and can determine a DSD electrotherapy. The DSD electrotherapy can be based at least in part on the physiological parameters, the indication for the administration of an electrotherapy or a review of the ECG data.

Abstract: In some implementations, a method includes retrieving data from multiple sensors in a computing device, and the multiple sensors comprise different types of sensors. The sensor data is analyzed based on a predictive model, and the predictive model is trained to detect malware. Initiation of malware is determined based on the analysis. In response to the determination, the malware is terminated.

Abstract: A method and apparatus for protecting property, wherein the method comprises receiving information indicating an attack on the property, determining, from the received information, a type of attack upon the property indicated by the received information, and transmitting a data packet to a receiver, the data packet comprising metadata describing the determined type of attack.

Abstract: A method (500) for protection of a vehicle (100), the method comprising: receiving information from a sensor (502); comparing the information with known signatures indicative of a likely attack (504); determining whether a known signature indicative of a likely attack is present (506); and if a known signature indicative of a likely attack is present, placing at least one system of the vehicle into a heightened state of alert (508).

Abstract: A multiple-antenna positioning system with a single drive element, providing reduced weight and complexity over systems that have a drive element for each antenna. In certain examples, each antenna can be coupled with a rotating spindle, with each antenna spindle being coupled with a pair of link arms. By driving a single drive spindle, each of the antenna spindles in the system can be rotated by the associated pair of link arms. The link arms can have an adjustable length, such as through a turnbuckle mechanism, to reduce backlash in the system, and in some examples can apply a preload to the system. By reducing backlash, the multiple antenna positioning system can have improved responsiveness to a rotation of the single drive element, as well as improved stability of the positioning of each antenna when the drive element is held in a fixed position.

Abstract: The present invention is directed to antibodies and fragments thereof having binding specificity for ACTH. Embodiments of this invention relate to the binding fragments of antibodies described herein, comprising the sequences of the VH, VL and/or CDR polypeptides described herein, and the polynucleotides encoding them. The invention also contemplates anti-ACTH antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. The invention further contemplates methods of making said anti-ACTH antibodies and binding fragments thereof.

Abstract: A clinical dashboard device, system, method for providing clinical data for clinical dashboard display on a device is disclosed. The system includes a server for providing clinical dashboard data, which may include data from one or more defibrillators, and further includes a clinical dashboard device. The clinical dashboard device includes a processor, a communication module configured for enabling communication between the processor and the server for receiving the clinical dashboard data from the server, and a clinical dashboard client. The clinical dashboard client includes a clinical dashboard data manager module including an instance of a clinical dashboard data manager service that provides managed clinical dashboard data between one or more clinical dashboard applications and the server. The instance of the clinical dashboard data manager service further provides managed display of managed clinical dashboard data on the display of the clinical dashboard device.

Abstract: An electro-discharge machining (EDM) device comprises a housing, an erosion electrode, a ground electrode, and a dielectric inlet. The housing is configured to be positioned on a surface of a workpiece and proximal to a fastener to be eroded. The planar erosion electrode is positioned at least partially within the housing, with the erosion electrode being movable relative to the housing in a first axis. The first axis is substantially normal to a longitudinal axis of the fastener. The ground electrode is conductively connected to the fastener. The dielectric inlet is configured to deliver a dielectric fluid to a region between the erosion electrode and the fastener.

Abstract: A defibrillation device for administering an electrotherapy, such as a dual-sequential defibrillation (DSD) electrotherapy. The defibrillation device can include a defibrillation therapy module, a physiological parameter module and a control module. The defibrillation therapy module can output one or more energies and the physiological parameter module can receive one or more physiological parameters, including electrocardiogram (ECG) data. The control module can analyze the physiological parameters to determine an indication for the administration of an electrotherapy and can determine a DSD electrotherapy. The DSD electrotherapy can be based at least in part on the physiological parameters, the indication for the administration of an electrotherapy or a review of the ECG data.

Abstract: The present disclosure relates to gastrointestinal (GI) tract detection methods, devices and systems.

Abstract: Medical device, system, method for capturing medical images includes an image capture and processing portion and an interchangeable medical tool portion. The image capture and processing portion is configured to capture and process a photo image, a video stream of images, or a coded image. The interchangeable medical tool portion is configured to connect to the image capture and processing portion. The image capture and processing portion further includes a configuration module configured to detect a connection of the medical tool portion to the image capture and processing portion, determine the type of the interchangeable medical tool portion connected, and adapt the image capture and processing portion to the detected type of the medical tool portion. The medical device may transmit medical images to an external device for interpretation by an expert, providing coaching to the user of the medical device, and for asset management, decision support, and/or other purposes.

Abstract: The disclosure relates to modulating pyruvate kinase and provides novel chemical compounds of formula (I) useful as activators of PKR, as well as various uses of these compounds. PKR activating compounds are useful in the treatment of diseases and disorders associated with PKR and/or PKM2, such as pyruvate kinase deficiency (PKD), sickle cell disease (SCD), and thalassemia.

Abstract: A computing architecture, system and method are disclosed for use in a medical device for providing decision support to a caregiver. The computing architecture includes a memory, a processor in communication with the memory, and an instance of a primary rules-based service configured to provide instruction events, the instance providing a primary processing thread of instruction events for coaching treatment of a patient. A software manager module includes an artificial intelligence architecture. The artificial intelligence architecture is configured to provide an instance of a conditional rules-based service for providing instruction events. The instance provided by the artificial intelligence architecture provides a processing thread of instruction events for coaching treatment of a patient that is independent of the primary processing thread and is configured to trigger an action on the occurrence of a pre-defined set of input conditions.

Abstract: A multiple-antenna positioning system with a single drive element, providing reduced weight and complexity over systems that have a drive element for each antenna. In certain examples, each antenna can be coupled with a rotating spindle, with each antenna spindle being coupled with a pair of link arms. By driving a single drive spindle, each of the antenna spindles in the system can be rotated by the associated pair of link arms. The link arms can have an adjustable length, such as through a turnbuckle mechanism, to reduce backlash in the system, and in some examples can apply a preload to the system. By reducing backlash, the multiple antenna positioning system can have improved responsiveness to a rotation of the single drive element, as well as improved stability of the positioning of each antenna when the drive element is held in a fixed position.