Patents by Inventor Mitchell Avery

Mitchell Avery has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240423958
    Abstract: C-7 functionalized artemisinin derivatives, and methods of producing and using C-7 functionalized artemisinin derivatives, for the treatment of malaria. Semi-synthesis of artemisinin analogs based on the functionalization of C-7 through fungal biotransformation. Fungal fermentation techniques were used to add hydroxyl groups to artemisinin positions that are difficult to access chemical, namely C-7.
    Type: Application
    Filed: June 14, 2024
    Publication date: December 26, 2024
    Inventors: Paulo Carvalho, Karine Le Roch, Mitchell Avery, John Williamson, Amar Chittiboyina, Matthew Valdez, Zeinab Chahine, Melinda Baldwin
  • Publication number: 20090192152
    Abstract: The present invention provides a method of preventing or treating one or more of the following medical conditions, or treating symptoms of one or more of the following medical conditions: amebic infections, giardiasis, estrogen deficient states, osteoporosis, cardiovascular heart disease, high cholesterol levels, hyperlipidemia, cancer by administering to a subject having, or predisposed to, one or more of the conditions, a therapeutically effective amount of a compound of the present invention and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: December 23, 2008
    Publication date: July 30, 2009
    Inventors: Mitchell Avery, Larry A. Walker, Nakul Telang
  • Patent number: 7468445
    Abstract: The present invention provides a method of preventing or treating one or more of the following medical conditions, or treating symptoms of one or more of the following medical conditions: amebic infections, giardiasis, estrogen deficient states, osteoporosis, cardiovascular heart disease, high cholesterol levels, hyperlipidemia, cancer by administering to a subject having, or predisposed to, one or more of the conditions, a therapeutically effective amount of a compound of the present invention and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: August 7, 2003
    Date of Patent: December 23, 2008
    Assignee: University of Mississippi
    Inventors: Mitchell Avery, Larry A. Walker, Nakul Telang
  • Publication number: 20070099969
    Abstract: This invention provides new chemical entities useful for treating a variety of clinical disorders including those that are influenced by the activity of peroxisome proliferator activated receptors (PPAR). The structures of the compounds and methods to design, make and use the compounds are provided. Compounds and methods for administering therapeutic compositions comprising the compounds in cases of the disease psoriasis are provided. An exemplary compound having the formula compound is 5adamantan-2-yl-pentanoic acid {2-[4-(2,4-dioxo-thiazolidin-5-yl-methyl)-phenoxy]-ethyl}-methyl-amide is provided.
    Type: Application
    Filed: July 21, 2004
    Publication date: May 3, 2007
    Inventors: Mitchell Avery, Harrihar Pershadsingh
  • Publication number: 20060106091
    Abstract: The present invention provides a method of preventing or treating one or more of the following medical conditions, or treating symptoms of one or more of the following medical conditions: amebic infections, giardiasis, estrogen deficient states, osteoporosis, cardiovascular heart disease, high cholesterol levels, hyperlipidemia, cancer by administering to a subject having, or predisposed to, one or more of the conditions, a therapeutically effective amount of a compound of the present invention and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: August 7, 2003
    Publication date: May 18, 2006
    Inventors: Mitchell Avery, Larry Walker, Nakul Telang
  • Publication number: 20050240034
    Abstract: Described herein is the synthesis, bioassay results and utility of new C-9 and C-10 substituted artemisinin derivatives with easily functionalizable groups attached to the artemisinin skeleton through carbon chain or heteroatoms. Described also is the demonstration of this class of compounds for their broad-spectrum anti-parasitic activity. Certain of these analogs possess noticeable cytotoxicity deliberately focused on treatment of cancerous diseases.
    Type: Application
    Filed: May 7, 2003
    Publication date: October 27, 2005
    Inventors: Mitchell Avery, Kannoth Muraleedharan
  • Publication number: 20050020654
    Abstract: The present invention provides novel compounds and pharmaceutical compositions thereof, which at least partially activate PPAR? and may further inhibit the activity of the AT1 receptor. The novel compounds include certain substituted benzimidazole compounds of Formulae I and II, infra. The invention also provides methods of treating inflammatory and metabolic disorders and methods for screening compounds for the capability to treat or prevent an inflammatory or metabolic disorder.
    Type: Application
    Filed: March 15, 2004
    Publication date: January 27, 2005
    Inventors: Harrihar Pershadsingh, Mitchell Avery