Patents by Inventor Mitchell Nambu

Mitchell Nambu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • JAK KINASE MODULATING COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20110269740
    Abstract: Provided herein are pyrrolotriazine compounds for treatment of JAK kinase, including JAK2 kinase mediated diseases. Also provided are pharmaceutical compositions comprising the compounds and methods of using the compounds and compositions.
    Type: Application
    Filed: July 2, 2009
    Publication date: November 3, 2011
    Inventors: Sunny Abraham, Qi Chao, Michael Hadd, Mark Holladay, Gang Liu, Mitchell Nambu, Eduardo Setti
  • 4-METHYLPYRIDOPYRIMIDINONE COMPOUNDS
    Publication number: 20080090801
    Abstract: The present invention is directed to novel 4-methylpyridopyrimidinone compounds of Formula (I), and to salts thereof, their synthesis, and their use as inhibitors of phosphoinositide 3-kinase alpha (PI3-K?).
    Type: Application
    Filed: September 13, 2007
    Publication date: April 17, 2008
    Inventors: Hengmiao Cheng, Dilip Bhumralkar, Klaus Dress, Jacqui Hoffman, Mary Johnson, Robert Kania, Phuong Le, Mitchell Nambu, Mason Pairish, Michael Plewe, Khanh Tran
  • Therapeutic Compounds
    Publication number: 20070167497
    Abstract: The present invention provides compounds of formula (I), or pharmaceutically acceptable salts or solvates thereof, methods for their preparation, methods for their use, and pharmaceutical formulations comprising them.
    Type: Application
    Filed: January 9, 2007
    Publication date: July 19, 2007
    Inventors: Mitchell Nambu, Leena Patel, Brian Patterson, Sylvie Sakata, John Tatlock
  • Aminoheteroaryl compounds as protein kinase inhibitors
    Publication number: 20070072874
    Abstract: Aminopyridine and aminopyrazine compounds of formula (1), compositions including these compounds, and methods of their use are provided. Preferred compounds of formula 1 have activity as protein kinase inhibitors, including as inhibitors of c-MET.
    Type: Application
    Filed: November 14, 2006
    Publication date: March 29, 2007
    Inventors: Jingrong Cui, Dilip Bhumralkar, Iriny Botrous, Ji Chu, Lee Funk, Cathleen Hanau, G. Harris, Lei Jia, Joanne Johnson, Stephen Kolodziej, Pei-Pei Kung, Xiaoyuan Li, Jason Lin, Jerry Meng, Mitchell Nambu, Christopher Nelson, Mason Pairish, Hong Shen, Michelle Tran-Dube, Allison Walter, Fang-Jie Zhang, Jennifer Zhang
  • Aminoheteroaryl compounds as protein kinase inhibitors
    Publication number: 20060178374
    Abstract: Aminoheteroaryl compounds are provided, as well as methods for their synthesis and use. Preferred compounds are potent inhibitors of the c-Met protein kinase, and are useful in the treatment of abnormal cell growth disorders, such as cancers.
    Type: Application
    Filed: August 26, 2005
    Publication date: August 10, 2006
    Inventors: Jingrong Cui, Lee Funk, Lei Jia, Pei-Pei Kung, Jerry Meng, Mitchell Nambu, Mason Pairish, Hong Shen, Michelle Tran-Dube
  • Pyrazole-substituted aminoheteroaryl compounds as protein kinase inhibitors
    Publication number: 20060128724
    Abstract: Compounds of formula 1 are provided, as well as methods for their synthesis and use. Preferred compounds are potent inhibitors of the c-Met protein kinase, and are useful in the treatment of abnormal cell growth disorders, such as cancers.
    Type: Application
    Filed: August 26, 2005
    Publication date: June 15, 2006
    Inventors: Jingrong Cui, Lee Funk, Lei Jia, Pei-Pei Kung, Jerry Meng, Mitchell Nambu, Mason Pairish, Hong Shen, Michelle Tran-Dube
  • Enantiomerically pure aminoheteroaryl compounds as protein kinase inhibitors
    Publication number: 20060046991
    Abstract: Enantiomerically pure compound of formula 1 are provided, as well as methods for their synthesis and use. Preferred compounds are potent inhibitors of the c-Met protein kinase, and are useful in the treatment of abnormal cell growth disorders, such as cancers.
    Type: Application
    Filed: August 26, 2005
    Publication date: March 2, 2006
    Inventors: Jingrong Cui, Lee Funk, Lei Jia, Pei-Pei Kung, Jerry Meng, Mitchell Nambu, Mason Pairish, Hong Shen, Michelle Tran-Dube
  • Aminoheteroaryl compounds as protein kinase inhibitors
    Publication number: 20050009840
    Abstract: Aminopyridine and aminopyrazine compounds of formula (1), compositions including these compounds, and methods of their use are provided. Preferred compounds of formula 1 have activity as protein kinase inhibitors, including as inhibitors of c-MET.
    Type: Application
    Filed: February 26, 2004
    Publication date: January 13, 2005
    Inventors: Jingrong Cui, Dilip Bhumralkar, Iriny Botrous, Ji Chu, Lee Funk, Cathleen Hanau, G. Harris, Lei Jia, Joanne Johnson, Stephen Kolodziej, Pei-Pei Kung, Xiaoyuan Li, Jason Lin, Jerry Meng, Mitchell Nambu, Christopher Nelson, Mason Pairish, Hong Shen, Michelle Tran-Dube, Allison Walter, Fang-Jie Zhang, Jennifer Zhang