Patents by Inventor Mitchell S. Wortzman

Mitchell S. Wortzman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10940107
    Abstract: The present disclosure provides a non-autologous product that is a mixture of two or more cells or tissue cultures of fibroblast, or extracts from cultures, or media cultures, isolated from separate individuals, either homogeneous or heterogeneous. The cells or factors are blended together in a product that imparts desired characteristics to the skin of a recipient who is not a source of the mixture. The present disclosure also relates to methods of making and using and/or culturing the fibroblasts including to optimize the potency of the mixture to impart one or more the desired characteristics to the skin of a recipient.
    Type: Grant
    Filed: November 14, 2014
    Date of Patent: March 9, 2021
    Assignee: Dermaforce Holdings, LLC
    Inventors: Jonah Shacknai, Mitchell S. Wortzman, David H. McDaniel
  • Publication number: 20170151149
    Abstract: There is provided a topical skin composition directed to one or more desired benefits. The composition includes one or more proteins selected based on the desired skin benefit to be derived by application of the topical skin composition. In one embodiment, each protein is from one donor group having two or more individuals. In another embodiment, the protein is from two or more donor group.
    Type: Application
    Filed: November 30, 2016
    Publication date: June 1, 2017
    Inventors: Jonah SHACKNAI, Mitchell S. WORTZMAN, David H. McDANIEL, Stephen NEWHART
  • Patent number: 9561241
    Abstract: The present disclosure relates to dosage forms and methods that enhance the absorption of minocycline in the gastrointestinal tract and thereby enhance bioavailability of the minocycline, and further provides methods of using these dosage forms for the treatment of conditions such as acne.
    Type: Grant
    Filed: June 28, 2012
    Date of Patent: February 7, 2017
    Assignee: Medicis Pharmaceutical Corporation
    Inventors: Douglas A. Bakan, Waranush Jitpraphai, Steven B. Newhard, Mitchell S. Wortzman
  • Patent number: 9119793
    Abstract: The present disclosure relates to dosage forms, e.g., swell, float and bioadhesive, and methods that enhance the absorption of doxycycline in the gastrointestinal tract. The oral dosage forms control the spatial and temporal delivery of doxycycline in the gastrointestinal tract. This controlled spatial and temporal delivery provides a site and rate of release, respectively, of the doxycycline into the gastrointestinal tract that enhances the amount of the doxycycline absorbed into the bloodstream.
    Type: Grant
    Filed: June 28, 2012
    Date of Patent: September 1, 2015
    Assignee: Medicis Pharmaceutical Corporation
    Inventors: Douglas A. Bakan, Waranush Jitpraphai, Steven B. Newhard, Mitchell S. Wortzman
  • Publication number: 20150132267
    Abstract: The present disclosure provides a non-autologous product that is a mixture of two or more cells or tissue cultures of fibroblast, or extracts from cultures, or media cultures, isolated from separate individuals, either homogeneous or heterogeneous. The cells or factors are blended together in a product that imparts desired characteristics to the skin of a recipient who is not a source of the mixture. The present disclosure also relates to methods of making and using and/or culturing the fibroblasts including to optimize the potency of the mixture to impart one or more the desired characteristics to the skin of a recipient.
    Type: Application
    Filed: November 14, 2014
    Publication date: May 14, 2015
    Inventors: Jonah SHACKNAI, Mitchell S. WORTZMAN, David H. McDANIEL
  • Patent number: 8778909
    Abstract: Methods for applying injectable fillers are provided. In some embodiments, the methods can extend effectiveness of the injectable filler. In some embodiments, the methods can provide for an elevated level of effectiveness of the injectable filler. In some embodiments, the methods can prolong the effectiveness of the injectable filler.
    Type: Grant
    Filed: May 31, 2013
    Date of Patent: July 15, 2014
    Assignee: Medicis Pharmaceutical Corporation
    Inventors: Mitchell S. Wortzman, Rhoda Narins, Xiaoming Lin
  • Publication number: 20130274223
    Abstract: Methods for applying injectable fillers are provided. In some embodiments, the methods can extend effectiveness of the injectable filler. In some embodiments, the methods can provide for an elevated level of effectiveness of the injectable filler. In some embodiments, the methods can prolong the effectiveness of the injectable filler.
    Type: Application
    Filed: May 31, 2013
    Publication date: October 17, 2013
    Inventors: Mitchell S Wortzman, Rhoda Narins, Xiaoming Lin
  • Patent number: 8455459
    Abstract: Methods for applying injectable fillers are provided. In some embodiments, the methods can extend effectiveness of the injectable filler. In some embodiments, the methods can provide for an elevated level of effectiveness of the injectable filler. In some embodiments, the methods can prolong the effectiveness of the injectable filler.
    Type: Grant
    Filed: August 1, 2008
    Date of Patent: June 4, 2013
    Assignee: Medicis Pharmaceutical Corporation
    Inventors: Mitchell S. Wortzman, Rhoda Narins, Xiaoming Lin
  • Publication number: 20120289490
    Abstract: The present invention comprises a composition, method of enhancing potency and method of delivering corticosteroids in a vehicle comprising at least two penetration enhancers, and solvents and emulsifiers. The propylene glycol and penetration enhancers are present in ratio to the total of the propylene glycol, penetration enhancers, and solvents and emulsifiers of at least about 0.70.
    Type: Application
    Filed: July 30, 2012
    Publication date: November 15, 2012
    Applicant: MEDICIS PHARMACEUTICAL CORPORATION
    Inventors: Eugene H. Gans, Mitchell S. Wortzman
  • Patent number: 8232264
    Abstract: The present invention comprises a composition, method of enhancing potency and method of delivering corticosteroids in a vehicle comprising at least two penetration enhancers, and solvents and emulsifiers. The propylene glycol and penetration enhancers are present in ratio to the total of the propylene glycol, penetration enhancers, and solvents and emulsifiers of at least about 0.70.
    Type: Grant
    Filed: January 29, 2009
    Date of Patent: July 31, 2012
    Assignee: Medicis Pharmaceutical Corporation
    Inventors: Eugene H. Gans, Mitchell S. Wortzman
  • Publication number: 20120115954
    Abstract: Embodiments of this invention relate to a composition containing both benzoyl peroxide and a retinoid. Additionally, it relates to the treatment of acne vulgaris by applying an aqueous gel comprising BPO and a retinoid.
    Type: Application
    Filed: January 18, 2012
    Publication date: May 10, 2012
    Applicant: MEDICIS PHARMACEUTICAL CORPORATION
    Inventors: Mitchell S. Wortzman, Waranush Jitpraphai, Manzer Durrani
  • Publication number: 20110082391
    Abstract: A method for measuring the effect of a medical treatment on the size of lips.
    Type: Application
    Filed: June 10, 2010
    Publication date: April 7, 2011
    Inventors: Michael A.C. Kane, Xiaoming Lin, Mitchell S. Wortzman, Stacy Smith, Zbigniew Paul Lorenc
  • Patent number: 7794738
    Abstract: The present invention comprises a composition, method of enhancing potency and method of delivering corticosteroids in a vehicle comprising at least two penetration enhancers, and solvents and emulsifiers. The propylene glycol and penetration enhancers are present in ratio to the total of the propylene glycol, penetration enhancers, and solvents and emulsifiers of at least about 0.70.
    Type: Grant
    Filed: January 24, 2007
    Date of Patent: September 14, 2010
    Assignee: Medicis Pharmaceutical Corporation
    Inventors: Eugene H. Gans, Mitchell S. Wortzman
  • Patent number: 7771733
    Abstract: The present invention comprises a composition, method of enhancing potency and method of delivering corticosteroids in a vehicle comprising at least two penetration enhancers, and solvents and emulsifiers. The propylene glycol and penetration enhancers are present in ratio to the total of the propylene glycol, penetration enhancers, and solvents and emulsifiers of at least about 0.70.
    Type: Grant
    Filed: January 24, 2007
    Date of Patent: August 10, 2010
    Assignee: Medicis Pharmaceutical Corporation
    Inventors: Eugene H. Gans, Mitchell S. Wortzman
  • Publication number: 20090204101
    Abstract: Methods for applying injectable fillers are provided. In some embodiments, the methods can result in a reduced risk of an adverse event occurring from the administration of the injectable filler. Also disclosed are devices and kits related to this method.
    Type: Application
    Filed: August 20, 2008
    Publication date: August 13, 2009
    Inventors: Mitchell S. Wortzman, Xiaoming Lin, Jurrian T. Strobos, Richard G. Glogau, Michael A.C. Kane
  • Publication number: 20090176750
    Abstract: The present invention comprises a composition, method of enhancing potency and method of delivering corticosteroids in a vehicle comprising at least two penetration enhancers, and solvents and emulsifiers. The propylene glycol and penetration enhancers are present in ratio to the total of the propylene glycol, penetration enhancers, and solvents and emulsifiers of at least about 0.70.
    Type: Application
    Filed: January 29, 2009
    Publication date: July 9, 2009
    Inventors: Eugene H. Gans, Mitchell S. Wortzman
  • Publication number: 20090131521
    Abstract: Embodiments of this invention relate to a composition containing both benzoyl peroxide and a retinoid. Additionally, it relates to the treatment of acne vulgaris by applying an aqueous gel comprising BPO and a retinoid.
    Type: Application
    Filed: October 20, 2008
    Publication date: May 21, 2009
    Inventors: Mitchell S. Wortzman, Waranush Jitpraphai, Manzer Durrani
  • Publication number: 20090035251
    Abstract: Methods for applying injectable fillers are provided. In some embodiments, the methods can extend effectiveness of the injectable filler. In some embodiments, the methods can provide for an elevated level of effectiveness of the injectable filler. In some embodiments, the methods can prolong the effectiveness of the injectable filler.
    Type: Application
    Filed: August 1, 2008
    Publication date: February 5, 2009
    Inventors: Mitchell S. Wortzman, Rhoda Narins, Xiaoming Lin
  • Patent number: 7220424
    Abstract: The present invention comprises a composition, method of enhancing potency and method of delivering corticosteroids in a vehicle comprising at least two penetration enhancers, and solvents and emulsifiers. The propylene glycol and penetration enhancers are present in ratio to the total of the propylene glycol, penetration enhancers, and solvents and emulsifiers of at least about 0.70.
    Type: Grant
    Filed: April 4, 2003
    Date of Patent: May 22, 2007
    Assignee: Medicis Pharmaceutical Corporation
    Inventors: Eugene H. Gans, Mitchell S. Wortzman
  • Patent number: 7217422
    Abstract: The present invention comprises a composition, method of enhancing potency and method of delivering corticosteroids in a vehicle comprising at least two penetration enhancers, and solvents and emulsifiers. The propylene glycol and penetration enhancers are present in ratio to the total of the propylene glycol, penetration enhancers, and solvents and emulsifiers of at least about 0.70.
    Type: Grant
    Filed: April 4, 2003
    Date of Patent: May 15, 2007
    Assignee: Medicis Pharmaceutical Corporation
    Inventors: Eugene H. Gans, Mitchell S. Wortzman