Patents by Inventor Mitchell Turker

Mitchell Turker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of identifying inhibitors of gene silencing in mammalian cells
    Patent number: 9034645
    Abstract: Disclosed herein are methods of identifying inhibitors of gene silencing or re-silencing, which can include repressing expression of a selectable marker gene in mammalian cells, treating the cells with at least one test compound, growing the cells under selective conditions, and quantifying the relative number of cells that live, wherein a change in the relative number of cells as compared to cells that were not treated with the test compound, identifies the compound as an inhibitor of gene silencing or re-silencing. Also disclosed herein are transgenic mice and isolated cell lines that are useful in the disclosed methods and kits for use in performing the disclosed methods.
    Type: Grant
    Filed: May 27, 2009
    Date of Patent: May 19, 2015
    Assignee: Oregon Health & Science University
    Inventors: Mitchell Turker, Jon A. Oyer
  • METHODS OF IDENTIFYING INHIBITORS OF GENE SILENCING IN MAMMALIAN CELLS
    Publication number: 20110088102
    Abstract: Disclosed herein are methods of identifying inhibitors of gene silencing or re-silencing, which can include repressing expression of a selectable marker gene in mammalian cells, treating the cells with at least one test compound, growing the cells under selective conditions, and quantifying the relative number of cells that live, wherein a change in the relative number of cells as compared to cells that were not treated with the test compound, identifies the compound as an inhibitor of gene silencing or re-silencing. Also disclosed herein are transgenic mice and isolated cell lines that are useful in the disclosed methods and kits for use in performing the disclosed methods.
    Type: Application
    Filed: May 27, 2009
    Publication date: April 14, 2011
    Inventor: Mitchell Turker