Patents by Inventor MITCHELL VAMOS

MITCHELL VAMOS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITORS OF ULK1/2 AND METHODS OF USING SAME
    Publication number: 20230135635
    Abstract: The present disclosure is directed to compounds, compositions, formulations and methods of use thereof in the treatment and prevention of ULK mediated diseases, including cancer.
    Type: Application
    Filed: February 12, 2021
    Publication date: May 4, 2023
    Inventors: Nicholas D.P. COSFORD, Nicole A. BAKAS, Mitchell VAMOS, Reuben J. SHAW, Allison S. LIMPERT, Sonja N. BRUN
  • MONO AND COMBINATION THERAPIES WITH ULK1/2 INHIBITORS
    Publication number: 20230130766
    Abstract: Provided herein are methods of treating diseases, including cancer, with ULK inhibitors, both as monotherapies and in combination with other therapeutic agents.
    Type: Application
    Filed: February 12, 2021
    Publication date: April 27, 2023
    Inventors: Nicholas D.P. COSFORD, Reuben J. SHAW, Nicole A. BAKAS, Allison S. LIMPERT, Sonja N. BRUN, Mitchell VAMOS
  • ULK1 inhibitors and methods using same
    Patent number: 10774092
    Abstract: In certain aspects, the invention provides a method for treating a disease or condition in a subject, the method comprising co-administering to a subject in need thereof a therapeutically effective amount of at least one ULK1-inhibiting pyrimidine, and a therapeutically effective amount of an mTOR inhibitor.
    Type: Grant
    Filed: April 19, 2019
    Date of Patent: September 15, 2020
    Assignees: SALK INSTITUTE FOR BIOLOGICAL STUDIES, SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, YALE UNIVERSITY
    Inventors: Reuben J. Shaw, Daniel F. Egan, Nicholas Cosford, Benjamin Turk, Mitchell Vamos, Dhanya Raveendra Panickar, Matthew Chun, Douglas Sheffler
  • ULK1 inhibitors and methods using same
    Patent number: 10689397
    Abstract: In certain aspects, the invention provides a method for treating a disease or condition in a subject, the method comprising co-administering to a subject in need thereof a therapeutically effective amount of at least one ULK1-inhibiting pyrimidine, and a therapeutically effective amount of an mTOR inhibitor.
    Type: Grant
    Filed: February 6, 2019
    Date of Patent: June 23, 2020
    Assignees: SALK INSTITUTE FOR BIOLOGICAL STUDIES, SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, YALE UNIVERSITY
    Inventors: Reuben J. Shaw, Daniel F. Egan, Nicholas Cosford, Benjamin Turk, Mitchell Vamos, Dhanya Raveendra Panickar, Matthew Chun, Douglas Sheffler
  • NOVEL ULK1 INHIBITORS AND METHODS USING SAME
    Publication number: 20190284207
    Abstract: In certain aspects, the invention provides a method for treating a disease or condition in a subject, the method comprising co-administering to a subject in need thereof a therapeutically effective amount of at least one ULK1-inhibiting pyrimidine, and a therapeutically effective amount of an mTOR inhibitor.
    Type: Application
    Filed: April 19, 2019
    Publication date: September 19, 2019
    Inventors: Reuben J. SHAW, Daniel F. EGAN, Nicholas COSFORD, Benjamin TURK, Mitchell VAMOS, Dhanya Raveendra PANICKAR, Matthew CHUN, Douglas SHEFFLER
  • NOVEL ULK1 INHIBITORS AND METHODS USING SAME
    Publication number: 20190248806
    Abstract: In certain aspects, the invention provides a method for treating a disease or condition in a subject, the method comprising co-administering to a subject in need thereof a therapeutically effective amount of at least one ULK1-inhibiting pyrimidine, and a therapeutically effective amount of an mTOR inhibitor.
    Type: Application
    Filed: April 19, 2019
    Publication date: August 15, 2019
    Inventors: Reuben J. SHAW, Daniel F. EGAN, Nicholas COSFORD, Benjamin TURK, Mitchell VAMOS, Dhanya Raveendra PANICKAR, Matthew CHUN, Douglas SHEFFLER
  • NOVEL ULK1 INHIBITORS AND METHODS USING SAME
    Publication number: 20190152989
    Abstract: In certain aspects, the invention provides a method for treating a disease or condition in a subject, the method comprising co-administering to a subject in need thereof a therapeutically effective amount of at least one ULK1-inhibiting pyrimidine, and a therapeutically effective amount of an mTOR inhibitor.
    Type: Application
    Filed: February 6, 2019
    Publication date: May 23, 2019
    Inventors: Reuben J. SHAW, Daniel F. EGAN, Nicholas COSFORD, Benjamin TURK, Mitchell VAMOS, Dhanya Raveendra PANICKAR, Matthew CHUN, Douglas SHEFFLER
  • ULK1 inhibitors and methods using same
    Patent number: 10266549
    Abstract: In certain aspects, the invention provides a method for treating a disease or condition in a subject, the method comprising co-administering to a subject in need thereof a therapeutically effective amount of at least one ULK1-inhibiting pyrimidine, and a therapeutically effective amount of an mTOR inhibitor.
    Type: Grant
    Filed: August 25, 2015
    Date of Patent: April 23, 2019
    Assignees: SALK INSTITUTE FOR BIOLOGICAL STUDIES, SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, YALE UNIVERSITY
    Inventors: Reuben J. Shaw, Daniel F. Egan, Nicholas Cosford, Benjamin Turk, Mitchell Vamos, Dhanya Raveendra Panickar, Matthew Chun, Douglas Sheffler
  • NOVEL ULK1 INHIBITORS AND METHODS USING SAME
    Publication number: 20170342088
    Abstract: In certain aspects, the invention provides a method for treating a disease or condition in a subject, the method comprising co-administering to a subject in need thereof a therapeutically effective amount of at least one ULK1-inhibiting pyrimidine, and a therapeutically effective amount of an mTOR inhibitor.
    Type: Application
    Filed: August 25, 2015
    Publication date: November 30, 2017
    Applicants: SALK INSTITUTE FOR BIOLOGICAL STUDIES, SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE, YALE UNIVERSITY
    Inventors: REUBEN J. SHAW, DANIEL F. EGAN, NICHOLAS COSFORD, BENJAMIN TURK, MITCHELL VAMOS, DHANYA RAVEENDRA PANICKAR, MATTHEW CHUN, DOUG SHEFFLER