Patents by Inventor Mitsuaki Takeuchi
Mitsuaki Takeuchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9586905Abstract: A compound having a V2 receptor agonistic activity is provided. Providing a pharmaceutical composition which contains, as an active ingredient, a compound represented by general formula (I) described below: [R1 is formula described below: (A is a lower alkylene group which may be substituted with lower alkyl group; R6 is a hydrogen atom; R7 is a hydroxyl group, an aromatic heterocyclic group which may be substituted with lower alkyl group, carbamoyl group); R2 is a hydrogen atom or lower alkyl group; R3 is lower alkyl group which may be substituted with 1-3 fluorine atoms, or halogen atom; R4 is a five-membered aromatic monocyclic heterocyclic group, five-membered non-aromatic monocyclic heterocyclic group, (provided each heterocyclic groups contain at least one nitrogen atom and may be substituted with a lower alkyl group); and R5 is a lower alkyl group, halogen atom], or pharmacologically acceptable salt thereof.Type: GrantFiled: December 26, 2013Date of Patent: March 7, 2017Assignee: SANWA KAGAKU KENKYUSHO CO., LTD.Inventors: Katsunori Kitamoto, Nobuyoshi Kasugai, Hiroyo Kataoka, Yasushi Ohsawa, Yuka Kuno, Hiroki Fujieda, Keita Sakai, Hiroki Nagano, Naoki Takahashi, Toru Izuchi, Mitsuaki Takeuchi, Daisuke Kurumazuka, Toshiyuki Miyazawa, Satoko Harada, Izumi Gotoh, Yukiyasu Asano, Yurie Yamada, Morio Okabe
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Publication number: 20150291533Abstract: A compound having a V2 receptor agonistic activity is provided. Providing a pharmaceutical composition which contains, as an active ingredient, a compound represented by general formula (I) described below: [R1 is formula described below: (A is a lower alkylene group which may be substituted with lower alkyl group; R6 is a hydrogen atom; R7 is a hydroxyl group, an aromatic heterocyclic group which may be substituted with lower alkyl group, carbamoyl group); R2 is a hydrogen atom or lower alkyl group; R3 is lower alkyl group which may be substituted with 1-3 fluorine atoms, or halogen atom; R4 is a five-membered aromatic monocyclic heterocyclic group, five-membered non-aromatic monocyclic heterocyclic group, (provided each heterocyclic groups contain at least one nitrogen atom and may be substituted with a lower alkyl group); and R5 is a lower alkyl group, halogen atom], or pharmacologically acceptable salt thereof.Type: ApplicationFiled: December 26, 2013Publication date: October 15, 2015Inventors: Katsunori Kitamoto, Nobuyoshi Kasugai, Hiroyo Kataoka, Yasushi Ohsawa, Yuka Kuno, Hiroki Fujieda, Keita Sakai, Hiroki Nagano, Naoki Takahashi, Toru Izuchi, Mitsuaki Takeuchi, Daisuke Kurumazuka, Toshiyuki Miyazawa, Satoko Harada, Izumi Gotoh, Yukiyasu Asano, Yurie Yamada, Morio Okabe
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Publication number: 20130123460Abstract: The present invention aims at providing a peptide fragment capable of improving biostability of a bioactive substance while maintaining the activity of the bioactive substance, and a bioactive substance to which the peptide fragment is added. The present invention relates to a partial peptide of a GA module having 5 to 25 amino acids, including a partial sequence of a GA module (SEQ ID NO: 1) and the amino acid sequence Ile-Asp-Glu-Ile-Leu (SEQ ID NO: 2), and a bioactive complex in which the partial peptide of the GA module is bound to a bioactive substance. The bioactive substance includes GLP-1, GLP-2, GIP, VIP, somatostatin, amylin, ghrelin, derivatives thereof, and the like.Type: ApplicationFiled: April 28, 2011Publication date: May 16, 2013Applicant: SANWA KAGAKU KENKYUSHO CO., LTD.Inventors: Masayuki Okamoto, Ryuhji Okamoto, Tomohiro Shigemori, Takayo Murase, Atsushi Miyachi, Mitsuaki Takeuchi, Miyuki Tamura, Hiroshi Kinoshita
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Patent number: 7345180Abstract: A dipeptidyl peptidase IV inhibitor which is satisfactory in respect of activity, stability and safety and has an excellent action as a pharmaceutical agent. A compound represented by the following general formula or a pharmaceutically acceptable salt thereof: wherein R1 and R2 each represents hydrogen, an optionally substituted C1-6 alkyl group, or —COOR5 whereupon R5 represents hydrogen or an optionally substituted C1-6 alkyl group, or R1, R2, and a carbon atom together represent a 3- to 6-membered cycloalkyl group, R3 represents hydrogen or an optionally substituted C6-10 aryl group, R4represents a hydrogen or a cyano group, D represents —CONR6-, —CO— or —NR6CO—, R6 represents hydrogen or an optionally substituted C1-6 alkyl group, E represents —(CH2)m— whereupon m is 1 to 3, —CH2OCH2—, or —SCH2—, n is 0 to 3, and A represents an optionally substituted bicyclic heterocyclic group or bicyclic hydrocarbon group.Type: GrantFiled: January 30, 2004Date of Patent: March 18, 2008Assignee: Sanwa Kagaku Kenkyusho Co., Ltd.Inventors: Takuji Kakigami, Mitsuru Oka, Noriyasu Katoh, Masahiro Yoshida, Masahiro Shirai, Toru Murase, Masao Sakairi, Takayo Murase, Mitsuaki Takeuchi, Yuji Hayashi, Motohiro Takeda, Mitsuhiro Makino
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Publication number: 20060229286Abstract: A dipeptidyl peptidase IV inhibitor which is satisfactory in respect of activity, stability and safety and has an excellent action as a pharmaceutical agent. A compound represented by the following general formula or a pharmaceutically acceptable salt thereof: wherein R1 and R2 each represents hydrogen, an optionally substituted C1-6 alkyl group, or —COOR5 whereupon R5 represents hydrogen or an optionally substituted C1-6 alkyl group, or R1, R2, and a carbon atom together represent a 3- to 6-membered cycloalkyl group, R3 represents hydrogen or an optionally substituted C6-10 aryl group, R4 represents a hydrogen or a cyano group, D represents —CONR6—, —CO— or —NR6CO—, R6 represents hydrogen or an optionally substituted C1-6 alkyl group, E represents —(CH2)m— whereupon m is 1 to 3, —CH2OCH2—, or —SCH2—, n is 0 to 3, and A represents an optionally substituted bicyclic heterocyclic group or bicyclic hydrocarbon group.Type: ApplicationFiled: January 30, 2004Publication date: October 12, 2006Inventors: Takuji Kakigami, Mitsuru Oka, Noriyasu Katoh, Masahiro Yoshida, Masahiro Shirai, Toru Murase, Masao Sakairi, Takayo Murase, Mitsuaki Takeuchi, Yuji Hayashi, Motohiro Takeda, Mitsuhiro Makino
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Patent number: 6962926Abstract: Compounds of formula A and formula B: and their pharmaceutically acceptable salts, compositions comprising them, methods for their use, and their use in the preparation of medicaments. The compounds are antagonists of MCP-1 function, and are useful in the prevention and treatment of chronic or acute inflammatory or autoimmune diseases, such as multiple sclerosis, and in the prevention and treatment of allergic hypersensitivity disorders.Type: GrantFiled: August 8, 2003Date of Patent: November 8, 2005Assignees: Telik, Inc., Sanwa Kagaku Kenkyusho Co., Ltd.Inventors: Edgardo Laborde, Louise Robinson, Fanying Meng, Brian T. Peterson, Hugo O. Villar, Steven E. Anuskiewicz, Wenli Ma, Yukiharu Matsumoto, Kunihisa Baba, Hideaki Inagaki, Katsumasa Tanaka, Yoshiro Ishiwata, Shoji Yokochi, Masayuki Okamoto, Takashi Nakamura, Atsushi Miyachi, Mitsuaki Takeuchi, Kouji Matsushima
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Publication number: 20040198719Abstract: Compounds of formula A and formula B: 1Type: ApplicationFiled: August 8, 2003Publication date: October 7, 2004Inventors: Edgardo Laborde, Louise M. Robinson, Fanying Meng, Brian T. Peterson, Hugo O. Villar, Steven E. Anuskiewicz, Wenli Ma, Yukiharu Matsumoto, Kunihisa Baba, Hideaki Inagaki, Katsumasa Tanaka, Yoshiro Ishiwata, Shoji Yokochi, Masayuki Okamoto, Takashi Nakamura, Atsushi Miyachi, Mitsuaki Takeuchi, Kouji Matsushima
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Patent number: 6035282Abstract: An attaching unit attaches an additional-information packet to a collection of main information, wherein the additional-information packet comprises sensory information corresponding to sensory impressions of a human being that has processed the collection of main information, the sensory impressions being with respect to circumstances under which the collection of main information has been processed.Type: GrantFiled: August 12, 1998Date of Patent: March 7, 2000Assignee: Ricoh Company, Ltd.Inventors: Ryo Tamai, Hirofumi Endo, Mitsuaki Takeuchi, Reiko Itoh, Jun Ebata
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Patent number: 5819235Abstract: An attaching unit attaches an additional-information packet to a collection of main information, wherein the additional-information packet comprises sensory information corresponding to sensory impressions of a human being that has processed the collection of main information, the sensory impressions being with respect to circumstances under which the collection of main information has been processed.Type: GrantFiled: February 2, 1993Date of Patent: October 6, 1998Assignee: Ricoh Company, Ltd.Inventors: Ryo Tamai, Hirofumi Endo, Mitsuaki Takeuchi, Reiko Itoh, Jun Ebata
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Patent number: 5649188Abstract: A system for electronically storing and retrieving information. Information is scanned into the system and a user manually designates that the information is to be sorted using boxes which are like folders, sorted by date, or sorted by a card such as by cards which are arranged alphabetically. When the user manually indicates that the information is to be sorted by box, there is also an automatic sort by date and by card. In this case the card which is used is a temporary sort card which is automatically designated. When the user manually indicates that the sort is other than by box, the information is automatically sorted into a temporary box. After the information is stored and sorted, the information can be retrieved and printed, as desired. The system utilizes a scanner, processor, storage device and printer.Type: GrantFiled: August 19, 1993Date of Patent: July 15, 1997Assignee: Ricoh Company, Ltd.Inventors: Keiichi Nomura, Hirofumi Endo, Yasuhiro Ii, Yuko Ogasawara, Mitsuhiro Kawai, Yasuyoshi Onoue, Masahiro Kurita, Akira Imai, Mitsuaki Takeuchi