Patents by Inventor Mitsuaki Yoshida

Mitsuaki Yoshida has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Derivative of adult T cell leukemia virus antigen peptide
    Patent number: 4795805
    Abstract: Recombinant plasmids are constructed by inserting a DNA fragment coding for a fused protein of an adult T cell leukemia virus antigen peptide and an enzyme into a vector DNA. Microorganisms are transformed with the recombinant plasmid and thereafter cultured to express the fused protein. The fused protein is useful for the detection and diagnosis of adult T cell leukemia.
    Type: Grant
    Filed: October 2, 1987
    Date of Patent: January 3, 1989
    Assignees: Kyowa Hakko Kogyo Co., Ltd., Juridical Foundation, Japanese Foundation for Cancer Research
    Inventors: Seiga Itoh, Susumu Sekine, Tadatsugu Taniguchi, Mitsuaki Yoshida, Haruo Sugano
  • DNA complementary to RNA of human leukemia virus
    Patent number: 4778756
    Abstract: A viral genomic DNA and fragments thereof which are complementary to genomic RNA of human leukemia virus and a recombinant DNA molecules containing the genomic DNA or fragments thereof. The genomic DNA and fragments thereof and the recombinant DNA molecules are useful for the diagnosis, prevention and therapy of human leukemia.
    Type: Grant
    Filed: October 5, 1987
    Date of Patent: October 18, 1988
    Assignee: Juridical Foundation, Japanese Foundation for Cancer Research
    Inventors: Mitsuaki Yoshida, Haruo Sugano
  • Adult T cell leukemia virus antigen polypeptide
    Patent number: 4724258
    Abstract: Recombinant plasmids are constructed by inserting a DNA fragment containing the env gene of adult T cell leukemia virus or a part thereof into a vector DNA. Microorganisms are transformed with the recombinant plasmid and thereafter cultured to express the peptide. The antigen polypeptide encoded by the env gene is useful for the detection and diagnosis of adult T cell leukemia.
    Type: Grant
    Filed: January 29, 1985
    Date of Patent: February 9, 1988
    Assignee: Juridical Foundation, Japanese Foundation for Cancer Research
    Inventors: Mitsuaki Yoshida, Haruo Sugano
  • Human leukemia virus-related peptides, antibodies of the peptides and a process for production of the antibodies
    Patent number: 4525300
    Abstract: An antibody of a human leukemia virus-related peptide obtained by collecting an antibody produced in a mammal body by administering to the mammal an antigen prepared by reacting a human leukemia virus-related peptide selected from the group consisting of:(a) a peptide represented by formula (1):H-Tyr-Val-Glu-Pro-Thr-Ala-Pro-Gln-Val-Leu-H (1)(b) a peptide represented by formula (2):R-Ile-Pro-His-Pro-Lys-Asn-Ser-Ile-Gly-Gly-Glu-Val-OH (2)wherein R is the same as drefined above;(c) a peptide represented by formula (3):R-Thr-Trp-Thr-Pro-Lys-Asp-Lys-Thr-Lys-Val-Leu-OH (3)wherein R is the same as defined above;(d) a peptide represented by formula (4):H-Val-Val-Gln-Pro-Lys-Lys-Pro-Pro-Pro-Tyr-OH (4)(e) a peptide represented by formula (5):R-Met-Gly-Gln-Ile-Phe-Ser-Arg-Ser-Ala-Ser-Pro-OH (5)wherein R is the same as defined above; and(f) a peptide represented by formula (6):H-Tyr-Pro-Glu-Gly-Thr-Pro-Lys-Asp-Pro-Ile-Leu-Arg-Ser-Leu-OH (6)as a hapten, with a carrier in the presence of a hapten-carrier binding agent.
    Type: Grant
    Filed: September 23, 1983
    Date of Patent: June 25, 1985
    Assignees: Japanese Foundation for Cancer Research, Otsuka Pharmaceutical Co., Ltd.
    Inventors: Mitsuaki Yoshida, Haruo Sugano, Fumio Shimizu, Kenichi Imagawa