Abstract: An epoxysuccinamic acid derivartive represented by the formula: ##STR1## (wherein R.sup.1 is an alkyl group having 1 to 10 carbon atoms, a phenyl group or a benzyl group), a pharmaceutically acceptable salt thereof, and an intermediate thereof are disclosed The compound of Formula I is useful as a therapeutical agent for muscular atrophy diseases.

Abstract: An epoxysuccinic acid derivative represented by the formula ##STR1## wherein R.sup.1 is a hydrogen atom or an alkyl group containing 1 to 4 carbon atoms, and a pharmaceutically acceptable salt are useful as cathepsin B inhibitors.

Abstract: Cephalosporin derivatives represented by the general formula ##STR1## wherein R is a hydrogen atom or a lower alkyl group having 1 to 4 carbon atoms, R' is a hydrogen atom, a lower alkyl group having 1 to 4 carbon atoms, a cycloalkyl group having 5 or 6 carbon atoms or a benzyl group, or R and R' together with the nitrogen atom to which they are attached form a tetrahydropyridinyl group, a morpholinyl group or pyrroridinyl group, and the non-toxic salts thereof are disclosed. These compounds are useful as antibacterial agents.

Abstract: Cephalosporin derivatives represented by the general formula ##STR1## wherein X represents a halogen atom, a hydroxyl group, a cyano group, a trifluoromethyl group, an amino group, a lower alkylcarbonylamino group, a lower alkoxy group, a lower alkylthio group, a lower alkoxycarbonyl group, a carbamoyl group, a substituted carbamoyl group, a carbamoyloxy group, a lower alkylcarbonyl group, a lower alkenyl group, an ethynyl group, a thiocyanate group, an .alpha.-carboxyaminomethyl group, a phenyl group, a pyridinyl group or an aminothiazolyl group, and n is an integer of 1 to 3, and the non-toxic salts thereof, are disclosed. These compounds are useful as antibacterial agents.

Abstract: A device for imparting strain to a steel sheet by which deformed regions spaced at a desired distance and having a minute linear shape are continuously formed, comprising: a strain imparting roll having projected portions on the surface thereof; a press roll provided opposite to the strain imparting roll; a row of a plurality of groups of back-up rolls for pressing against the press rolls, provided with spaces of a desired distance therebetween in a longitudinal direction of the press roll; and a fluid pressure cylinder connected to each group of the back-up rolls via a bearing, and a fluid supply source connected to the fluid pressure cylinder.

Abstract: Cephalosporin derivatives represented by the general formula ##STR1## Wherein X represents a hydrogen atom, a lower alkyl group having 1 to 4 carbon atoms, an allyl group, a cycloalkyl group having 5 or 6 carbon atoms or a benzyl group, and the non-toxic salts thereof are disclosed. These compounds are useful as antibacterial agents.

Abstract: A continuous casting mold having the wall thickness of each of parts corresponding to a point where molten steel begins to solidify during continuous casting is arranged to be locally thinner than other parts of the mold. High frequency oscillation is applied to the locally thinned parts to vibrate them to a sufficient amplitude to prevent the seizure of a cast steel piece from taking place due to the heat thereof for improvement in the surface quality thereof.