Abstract: It is intended to provide a system of predicting the postoperative prognosis in a patient with breast cancer from the viewpoint of gene expression based on the data obtained by genome-wide and comprehensive analysis on gene expression in breast cancer. Expression of human genes is comprehensively analyzed by using a DNA microarray and gene expression functions in various breast cancer conditions are compared, thereby establishing a system of predicting the postoperative prognosis of breast cancer.

Abstract: It is intended to provide a system of predicting the postoperative prognosis in a patient with breast cancer from the viewpoint of gene expression based on the data obtained by genome-wide and comprehensive analysis on gene expression in breast cancer. Expression of human genes is comprehensively analyzed by using a DNA microarray and gene expression functions in various breast cancer conditions are compared, thereby establishing a system of predicting the postoperative prognosis of breast cancer.

Abstract: It is intended to provide a system of predicting the postoperative prognosis in a patient with breast cancer from the viewpoint of gene expression based on the data obtained by genome-wide and comprehensive analysis on gene expression in breast cancer. Expression of human genes is comprehensively analyzed by using a DNA microarray and gene expression functions in various breast cancer conditions are compared, thereby establishing a system of predicting the postoperative prognosis of breast cancer.

Abstract: It is intended to provide a system of predicting the postoperative prognosis in a patient with breast cancer from the viewpoint of gene expression based on the data obtained by genome-wide and comprehensive analysis on gene expression in breast cancer. Expression of human genes is comprehensively analyzed by using a DNA microarray and gene expression functions in various breast cancer conditions are compared, thereby establishing a system of predicting the postoperative prognosis of breast cancer.

Abstract: The present invention relates to methods for assessing risk of hypertension in als by identifying the molecular variants or haplotypes of the angiotensinogen (AGT) gene.

Abstract: The present invention provide a gene present in a commonly deleted region of a chromosome in breast and ovarian cancers and encoding a novel protein, the protein ("MDC protein") encoded by the gene and a method for the diagnosis of cancer by using an antibody combinable to the protein.A detailed genetic map of human chromosome 17 was constructed to analyze the chromosome in breast and ovarian cancer tissues, and a gene encoding a novel protein was cloned and its structure was determined. As a result of gene analysis using DNA probes derived from the gene, a gene mutation was confirmed in breast cancer tissues. Moreover, a transformant carrying a plasmid containing the gene was grown to obtain the MDC protein. Furthermore, a monoclonal antibody was prepared by using the protein as an antigen.

Abstract: The present invention provides an antibody encoded by a gene which is present in a commonly deleted region of a chromosome in breast and ovarian cancers. A monoclonal antibody was prepared by using the protein as antigen and can be utilized in clinical fields for diagnosing cancer.

Abstract: The present invention provide a gene present in a commonly deleted region of a chromosome in breast and ovarian cancers and encoding a novel protein, the protein ("MDC protein") encoded by the gene, a method for the diagnosis of cancer by using an antibody combinable to the protein, and others.A detailed genetic map of human chromosome 17 was constructed to analyze the chromosome in breast and ovarian cancer tissues, and a gene encoding a novel protein was cloned and its structure was determined. As a result of gene analysis using DNA probes derived from the gene, a gene mutation was confirmed in breast cancer tissues. Moreover, a transformant carrying a plasmid containing the gene was grown to obtain the MDC protein. Furthermore, a monoclonal antibody was prepared by using the protein as antigen.