Patents by Inventor Mitsuru Ohkubo

Mitsuru Ohkubo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190127089
    Abstract: A solar power generator overlies a solar power generator when stowed. A plurality of solar cells of the solar power generator includes first solar cells each having a corner at one end of one side, and second solar cells disposed adjacent to the first solar cells. Each of the second solar cells has a chamfered part at an end, corresponding to the one end, of a side facing the one side. When viewed along thickness direction D3 of a support, a cushioning part of the solar power generator is disposed between the corner of the first solar cell and the chamfered part of the second solar cell and projects more outwardly along the thickness direction D3 of the support than the plurality of solar cells.
    Type: Application
    Filed: May 11, 2016
    Publication date: May 2, 2019
    Applicant: Mitsubishi Electric Corporation
    Inventors: Naoko TOMODA, Hajime TAKEYA, Mitsuru OHKUBO, Shinobu KAWAKATSU, Kazuyoshi SEKI
  • Patent number: 8772283
    Abstract: The present invention provides an imidazooxazine compound represented by Formula (I) or a salt thereof, wherein A, B, C, and D are as defined in the specification.
    Type: Grant
    Filed: April 5, 2012
    Date of Patent: July 8, 2014
    Assignee: Taiho Pharmaceutical Co., Ltd.
    Inventors: Masayuki Nakamura, Kenji Niiyama, Kaori Kamijo, Mitsuru Ohkubo, Toshiyasu Shimomura
  • Publication number: 20140005185
    Abstract: The present invention provides an imidazooxazine compound represented by Formula (I) or a salt thereof, wherein A, B, C, and D are as defined in the specification.
    Type: Application
    Filed: April 5, 2012
    Publication date: January 2, 2014
    Applicant: TAIHO PHARMACEUTICAL CO., LTD.
    Inventors: Masayuki Nakamura, Kenji Niiyama, Kaori Kamijo, Mitsuru Ohkubo, Toshiyasu Shimomura
  • Patent number: 8519136
    Abstract: The present invention relates to a compound of formula I: wherein: R1 is a hydrogen atom, F, CN, etc.; R2 is CO, SO2, etc.; R3 is a phenyl which may be substituted; X1, X2, and X3 each independently CH, N, etc. provided, however, that among X1, X2 and X3, the number of nitrogen is 0 or 1; W is the following residue: wherein: W1, W2, and W3 each independently CH, N, etc., or a pharmaceutically acceptable salt or ester thereof.
    Type: Grant
    Filed: February 18, 2009
    Date of Patent: August 27, 2013
    Assignee: MSD K.K.
    Inventors: Tetsuya Kato, Nobuhiko Kawanishi, Takashi Mita, Katsumasa Nonoshita, Mitsuru Ohkubo
  • Patent number: 8492397
    Abstract: The present invention relates to a compound of Formula (I): wherein R1 is H or C1-2 alkyl; R2 is H or C1-3 alkyl; R3 and R4 are each independently H or C1-2 alkyl, where the alkyl may be substituted with one to three of the same or different substituents selected from R10; R5 is H, hydroxy, C1-2 alkyl, or OCH3; and R10 is F or Cl, or a pharmaceutically acceptable salt or ester thereof.
    Type: Grant
    Filed: March 12, 2010
    Date of Patent: July 23, 2013
    Assignees: Vertex Pharmaceuticals Incorporated, MSD K.K.
    Inventors: Hayley Binch, Masaya Hashimoto, Toshiharu Iwama, Nobuhiko Kawanishi, Michael Mortimore, Mitsuru Ohkubo, Tomoko Sunami
  • Patent number: 8367690
    Abstract: The present invention relates to a compound of Formula (I): wherein: R1 is H, —NHCOOR1a, C5-6 cycloalkyl, or phenyl; where the cycloalkyl and phenyl each independently may be substituted with one to three of the same or different substituents selected from R10; R1a is C1-3 alkyl which may be substituted with one to three of the same or different substituents selected from F and Cl; R2 is H, —COOH, —CH2 COOH, —COOR2a, or —CH2COOR2a; R2a is C1-2 alkyl, where the alkyl may be substituted with one to three of the same or different substituents selected from halogen atoms; R3 is H, C1-6 alkyl, where the alkyl may be substituted with one to three of the same or different substituents selected from R11; R10 is F, Cl, CF3, or C1-2 alkyl; R11 is halogen atom, hydroxy, or cyano; W is selected from: W2a is H, halogen atom, cyano, C1-2 alkyl, or C3-5 cycloalkyl, or a pharmaceutically acceptable salt or ester thereof.
    Type: Grant
    Filed: March 15, 2010
    Date of Patent: February 5, 2013
    Assignees: Vertex Pharmaceuticals Inc., MSD K.K.
    Inventors: Hayley Binch, Masaya Hashimoto, Michael Mortimore, Mitsuru Ohkubo, Tomoko Sunami
  • Patent number: 8263632
    Abstract: The present invention relates to a compound of Formula (I): wherein: n is 0 or 1; X is 0 or CH2; R1 is H or C1-2 alkyl; R2 is H or C1-3 alkyl; R3 and R4 are each independently H or C1-2 alkyl, where the alkyl may be substituted with one to three of the same or different substituents selected from R10; R5 is H or OCH3; R10 is F or Cl; or a pharmaceutically acceptable salt or ester thereof
    Type: Grant
    Filed: March 15, 2010
    Date of Patent: September 11, 2012
    Assignees: Vertex Pharmaceuticals Incoporated, MSD K.K.
    Inventors: Toshiharu Iwama, Nobuhiko Kawanishi, Michael Mortimore, Mitsuru Ohkubo, Tomoko Sunami
  • Publication number: 20120029004
    Abstract: The present invention relates to a compound of Formula (I): wherein: R1 is H or C1-2 alkyl; R2 is H or C1-3 alkyl; R3 and R4 are each independently H or C1-2 alkyl, where the alkyl may be substituted with one to three of the same or different substituents selected from R10; R5 is H, hydroxy, C1-2 alkyl, or OCH3; and R10 is F or Cl, or a pharmaceutically acceptable salt or ester thereof.
    Type: Application
    Filed: March 12, 2010
    Publication date: February 2, 2012
    Inventors: Hayley Binch, Masaya Hashimoto, Toshiharu Iwama, Nobuhiko Kawanishi, Michael Mortimore, Mitsuru Ohkubo, Tomoko Sunami
  • Patent number: 8101621
    Abstract: The present invention relates to a compound of general formula I: wherein: n1 and n2 are the same or different, and are 0 or 1; R is aryl, heteroaryl, etc.; Re is hydrogen atom or lower alkyl; two groups selected from four groups consisting of (i) either one of Ra1 and Ra1?, (ii) either one of Ra2 and Ra2?, (iii) either one of Rb1 and Rb1?, and (iv) either one of Rb2 and Rb2?, are combined to form —(CH2)n— where n is 1, 2 or 3; and among Ra1, Ra1?, Ra2, Ra2?, Rb1, Rb1?, Rb2 and Rb2?, the groups which do not form —(CH2)n— are each independently hydrogen atom, etc.; X1, X2, X3 and X4 are each independently CH, N, etc.; Y1, Y2, Y3 and Y4 are the same or different and are CH or N, etc.; W is a 5-membered aromatic heterocyclic group, or a pharmaceutically acceptable salt or ester thereof.
    Type: Grant
    Filed: April 25, 2007
    Date of Patent: January 24, 2012
    Assignee: MSD K.K.
    Inventors: Tetsuya Kato, Nobuhiko Kawanishi, Takashi Mita, Keita Nagai, Katsumasa Nonoshita, Mitsuru Ohkubo
  • Publication number: 20120015940
    Abstract: The present invention relates to a compound of Formula (I): wherein: n is 0 or 1; X is O or CH2; R1 is H or C1-2 alkyl; R2 is H or C1-3 alkyl; R3 and R4 are each independently H or C1-2 alkyl, where the alkyl may be substituted with one to three of the same or different substituents selected from R10 R5 is H or OCH3; R10 is F or Cl; or a pharmaceutically acceptable salt or ester thereof.
    Type: Application
    Filed: March 15, 2010
    Publication date: January 19, 2012
    Inventors: Toshiharu Iwama, Nobuhiko Kawanishi, Michael Mortimore, Mitsuru Ohkubo, Tomoko Sunami
  • Publication number: 20120015969
    Abstract: The present invention relates to a compound of Formula (I): wherein: R1 is H, —NHCOOR1a, C5-6 cycloalkyl, or phenyl; where the cycloalkyl and phenyl each independently may be substituted with one to three of the same or different substituents selected from R10; R1a is C1-3 alkyl which may be substituted with one to three of the same or different substituents selected from F and Cl; R2 is H, —COOH, —CH2 COOH, —COOR2a, or —CH2COOR2a; R2a is C1-2 alkyl, where the alkyl may be substituted with one to three of the same or different substituents selected from halogen atoms; R3 is H, C1-6 alkyl, where the alkyl may be substituted with one to three of the same or different substituents selected from R11; R10 is F, Cl, CF3, or C1-2 alkyl; R11 is halogen atom, hydroxy, or cyano; W is selected from: W2a is H, halogen atom, cyano, C1-2 alkyl, or C3-5 cycloalkyl, or a pharmaceutically acceptable salt or ester thereof.
    Type: Application
    Filed: March 15, 2010
    Publication date: January 19, 2012
    Inventors: Hayley Binch, Masaya Hashimoto, Michael Mortimore, Mitsuru Ohkubo, Tomoko Sunami
  • Patent number: 7935712
    Abstract: The invention relates to a compound of a formula (I): or a pharmaceutically acceptable salt or ester thereof, useful as a therapeutic agent for various ACC-related disorders.
    Type: Grant
    Filed: July 14, 2006
    Date of Patent: May 3, 2011
    Assignees: Merck Sharp & Dohme Corp., MSD K.K.
    Inventors: Takeru Yamakawa, Hideki Jona, Kenji Niiyama, Koji Yamada, Tomoharu Iino, Mitsuru Ohkubo, Hideaki Imamura, Jun Shibata, Jun Kusunoki, Lihu Yang
  • Patent number: 7915263
    Abstract: The present invention relates to a compound of formula I: wherein: R1 is a hydrogen atom, F, CN, etc.; R1? is a hydrogen atom or lower alkyl which may be substituted; R2 is O, S, SO, SO2, etc.; R3 is a phenyl which may be substituted; X1, X2, and X3 each independently CH, N, etc. provided, however, that among X1, X2 and X3, the number of nitrogen is 0 or 1; W is the following residue: wherein: W1, W2, and W3 each independently CH, N, etc., or a pharmaceutically acceptable salt or ester thereof.
    Type: Grant
    Filed: August 29, 2007
    Date of Patent: March 29, 2011
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Yoshikazu Iwasawa, Tetsuya Kato, Nobuhiko Kawanishi, Kouta Masutani, Takashi Mita, Katsumasa Nonoshita, Mitsuru Ohkubo
  • Publication number: 20110003833
    Abstract: The present invention relates to a compound of formula I: wherein: R1 is a hydrogen atom, F, CN, etc.; R2 is CO, SO2, etc.; R3 is a phenyl which may be substituted; X1, X2, and X3 each independently CH, N, etc. provided, however, that among X1, X2 and X3, the number of nitrogen is 0 or 1; W is the following residue: wherein: W1, W2, and W3 each independently CH, N, etc., or a pharmaceutically acceptable salt or ester thereof.
    Type: Application
    Filed: February 18, 2009
    Publication date: January 6, 2011
    Inventors: Tetsuya Kato, Nobuhiko Kawanishi, Takashi Mita, Katsumasa Nonoshita, Mitsuru Ohkubo
  • Patent number: 7834018
    Abstract: The present invention relates to a compound represented by the general formula (I): wherein m1 and m2 are 1, 2, or 3; n1 and n2 are 0 or 1; i is an integer of any of 1 to m1; j is an integer of 1 to m2; R is aryl, heteroaryl, or cycloalkyl any of which may be substituted; Rai and Rai? is hydrogen atom, etc. and Rbj and Rbj? is hydrogen atom, etc.; Rc, Rd, and Re are hydrogen atom, etc; X1 is CH, CX1a, or N; X2 is CH, N, etc.; X3 is CH, N, etc.; X4 is CH or N; Y1, Y2, and Y3 are each independently CH or N; Z1 and Z2 are each independently CH or N; W is a 5-membered aromatic heterocyclic group such as pyrazolyl, thiazolyl, etc., or a pharmaceutically acceptable salt or ester thereof; a pharmaceutical composition or antitumor agent containing the same; and combinations of the antitumor agent with other antitumor agent(s).
    Type: Grant
    Filed: December 3, 2008
    Date of Patent: November 16, 2010
    Assignee: Banyu Pharmaceutical Co., Ltd
    Inventors: Mitsuru Ohkubo, Tetsuya Kato, Nobuhiko Kawanishi, Takashi Mita, Toshiyasu Shimomura
  • Publication number: 20100016335
    Abstract: The present invention relates to a compound of formula I: wherein: R1 is a hydrogen atom, F, CN, etc.; R1? is a hydrogen atom or lower alkyl which may be substituted; R2 is O, S, SO, SO2, etc.; R3 is a phenyl which may be substituted; X1, X2, and X3 each independently CH, N, etc. provided, however, that among X1, X2 and X3, the number of nitrogen is 0 or 1; W is the following residue: wherein: W1, W2, and W3 each independently CH, N, etc., or a pharmaceutically acceptable salt or ester thereof.
    Type: Application
    Filed: August 29, 2007
    Publication date: January 21, 2010
    Inventors: Yoshikazu Iwasawa, Tetsuya Kato, Nobuhiko Kawanishi, Kouta Masutani, Takashi Mita, Katsumasa Nonoshita, Mitsuru Ohkubo
  • Publication number: 20090192174
    Abstract: The present invention relates to a compound of general formula I: wherein: n1 and n2 are the same or different, and are 0 or 1; R is aryl, heteroaryl, etc.; Re is hydrogen atom or lower alkyl; two groups selected from four groups consisting of (i) either one of Ra1 and Ra1?, (ii) either one of Ra2 and Ra2?, (iii) either one of Rb1 and Rb1?, and (iv) either one of Rb2 and Rb2?, are combined to form —(CH2)n— where n is 1, 2 or 3; and among Ra1, Ra1?, Ra2, Ra2?, Rb1, Rb1?, Rb2 and Rb2?, the groups which do not form —(CH2)n— are each independently hydrogen atom, etc.; X1, X2, X3 and X4 are each independently CH, N, etc.; Y1, Y2, Y3 and Y4 are the same or different and are CH or N, etc.; W is a 5-membered aromatic heterocyclic group, or a pharmaceutically acceptable salt or ester thereof.
    Type: Application
    Filed: April 25, 2007
    Publication date: July 30, 2009
    Applicant: BANYU PHARMACEUTICAL CO., LTD.
    Inventors: Tetsuya Kato, Nobuhiko Kawanishi, Takashi Mita, Keita Nagai, Katsumasa Nonoshita, Mitsuru Ohkubo
  • Publication number: 20090149470
    Abstract: The present invention relates to a compound represented by the general formula (I): wherein m1 and m2 are 1, 2, or 3; n1 and n2 are 0 or 1; i is an integer of any of 1 to m1; j is an integer of 1 to m2; R is aryl, heteroaryl, or cycloalkyl any of which may be substituted; Rai and Rai? is hydrogen atom, etc. and Rbj and Rbj? is hydrogen atom, etc.; Rc, Rd, and Re are hydrogen atom, etc; X1 is CH, CX1a, or N; X2 is CH, N, etc.; X3 is CH, N, etc.; X4 is CH or N; Y1, Y2, and Y3 are each independently CH or N; Z1 and Z2 are each independently CH or N; W is a 5-membered aromatic heterocyclic group such as pyrazolyl, thiazolyl, etc., or a pharmaceutically acceptable salt or ester thereof; a pharmaceutical composition or antitumor agent containing the same; and combinations of the antitumor agent with other antitumor agent(s).
    Type: Application
    Filed: December 3, 2008
    Publication date: June 11, 2009
    Inventors: Mitsuru Ohkubo, Tetsuya Kato, Nobuhiko Kawanishi, Takashi Mita, Toshiyasu Shimomura
  • Publication number: 20090131464
    Abstract: The invention relates to a compound of a formula (I): or a pharmaceutically acceptable salt or ester thereof, useful as a therapeutic agent for various ACC-related disorders.
    Type: Application
    Filed: July 14, 2006
    Publication date: May 21, 2009
    Inventors: Takeru Yamakawa, Hideki Jona, Kenji Niiyama, Koji Yamada, Tomoharu Iino, Mitsuru Ohkubo, Hideaki Imamura, Jun Shibata, Jun Kusunoki, Lihu Yang
  • Patent number: 7491720
    Abstract: The present invention relates to a compound represented by the general formula (I): wherein m1 and m2 are 1, 2, or 3; n1 and n2 are 0 or 1; i is an integer of any of 1 to m1; j is an integer of 1 to m2; R is aryl, heteroaryl, or cycloalkyl any of which may be substituted; Rai and Rai? is hydrogen atom, etc. and Rbj and Rbj? is hydrogen atom, etc.; Rc, Rd, and Re are hydrogen atom, etc; X1 is CH, CX1a, or N; X2 is CH, N, etc.; X3 is CH, N, etc.; X4 is CH or N; Y1, Y2, and Y3 are each independently CH or N; Z1 and Z2 are each independently CH or N; W is a 5-membered aromatic heterocyclic group such as pyrazolyl, thiazolyl, etc., or a pharmaceutically acceptable salt or ester thereof; a pharmaceutical composition or antitumor agent containing the same; and combinations of the antitumor agent with other antitumor agent(s).
    Type: Grant
    Filed: October 25, 2005
    Date of Patent: February 17, 2009
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Mitsuru Ohkubo, Tetsuya Kato, Nobuhiko Kawanishi, Takashi Mita, Toshiyasu Shimomura