Patents by Inventor Mitsuru Okatake

Mitsuru Okatake has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for drying anhydrous paroxetine hydrochloride
    Patent number: 6541637
    Abstract: A process for drying paroxetine hydrochloride anhydrate comprising (A) reacting a paroxetine compound with hydrogen chloride in the presence of isopropyl alcohol and crystallizing the resulting product, to obtain paroxetine hydrochloride anhydrate, and drying the resulting paroxetine hydrochloride anhydrate at a temperature of not more than 60° C. and under normal pressure or lower in an atmosphere which does not substantially contain moisture until the content of isopropyl alcohol attains to not more than 15% by weight; and (B) further drying the paroxetine hydrochloride anhydrate at a temperature of 80° to 110°C. in an atmosphere reduced to not more than 20 mm Hg until the content of isopropyl alcohol attains to not more than 5% by weight.
    Type: Grant
    Filed: December 13, 1999
    Date of Patent: April 1, 2003
    Assignee: Sumika Fine Chemicals Co., Ltd.
    Inventors: Mitsuru Okatake, Taro Ishibashi, Yoshihiro Kawata