Abstract: An anti-inflammatory analgesic adhesive preparation is disclosed, comprising a flexible support having laminated thereon a pressure-sensitive adhesive material layer which contains Diclofenac Sodium and an organic acid such as citric acid. This adhesive preparation has excellent percutaneous absorption properties.

Abstract: A composition capable of promoting the skin permation or percutaneous absorption of a medicament, which comprises at least one adjuvant selected from the group consisting of a saturated hydrocarbon containing 5 to 20 carbon atoms which may be substituted by halogen, an alcohol ester of aliphatic carboxylic acid containing 12 to 18 carbon atoms, an ether, a dimethylpolysiloxane having a viscosity at 25.degree. C. of not more than 6 centistokes and a cyclic polydimethylsiloxane having a viscosity at 25.degree. C. of not more than 6 centistokes, and an imidazolidinone derivative represented by the general formula: ##STR1## wherein R.sub.1 and R.sub.2 each are a lower alkyl group; and pharmaceutical composition for external medication.

Abstract: A composition capable of promoting the skin permeation or percutaneous absorption of a drug, which comprises a lower alcohol and at least one member of the group consisting of a saturated aliphatic hydrocarbon containing 5 to 20 carbon atoms, which may optionally be halogen-substituted, a monohydric alcohol ester of an aliphatic carboxylic acid, which contains 13 to 24 carbon atoms, and an ether containing 8 to 16 carbon atoms with one ether bondage in the molecule; and an external preparation containing the above composition as a base.

Abstract: An antiphlogistic analgesic adhesive which comprisesa flexible substrate andan indomethacin containing pressure-sensitive adhesive layer closely contacting said flexible substrate, wherein said pressure-sensitive adhesive layer comprises a mixture of(a) indomethacin,(b) a copolymer of (i) an alkyl acrylate having 4 to 11 carbon atoms in the alkyl moiety and (ii) a functional monomer having a functional group in the molecule thereof and/or a vinyl monomer, which has pressure-sensitive adhesive properties at room temperature, and(c) an absorption accelerating assistant which maintains said indomethacin in a solubilized state in said copolymer and has skin diffusibility.