Patents by Inventor Mitsutaka Isobe

Mitsutaka Isobe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stabilized solid pharmaceutical preparation and method of producing the same
    Patent number: 5726180
    Abstract: To stabilize the active ingredients, a caffeine is incorporated into a solid pharmaceutical preparation comprising a dextromethorphan and a phenylpropanolamine. The pharmaceutical preparation may further comprise ibuprofen. The active ingredients may be further stabilized, in combination with the incorporation of the caffeine, by grouping and incorporating separately each or suitably combined plural of the active ingredients into different groups or by minimizing the amount of any reducing sugar such as lactose. The solid pharmaceutical preparation is practically valuable since decomposition of each active ingredient with the lapse of time is remarkably suppressed and the active ingredients are stabilized for a longer period of time.
    Type: Grant
    Filed: October 30, 1996
    Date of Patent: March 10, 1998
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Masahiko Kurihara, Shunichi Itoh, Kou Moriyama, Mitsutaka Isobe, Kenichiro Kiyoshima
  • Stabilized solid pharmaceutical preparation and method of producing the same
    Patent number: 5629316
    Abstract: To stabilize the active ingredients, a caffeine is incorporated into a solid pharmaceutical preparation comprising a dextromethorphan and a phenylpropanolamine. The pharmaceutical preparation may further comprise ibuprofen. The active ingredients may be further stabilized, in combination with the incorporation of the caffeine, by grouping and incorporating separately each or suitably combined plural of the active ingredients into different groups or by minimizing the amount of any reducing sugar such as lactose. The solid pharmaceutical preparation is practically valuable since decomposition of each active ingredient with the lapse of time is remarkably suppressed and the active ingredients are stabilized for a longer period of time.
    Type: Grant
    Filed: June 28, 1994
    Date of Patent: May 13, 1997
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Masahiko Kurihara, Shunichi Itoh, Kou Moriyama, Mitsutaka Isobe, Kenichiro Kiyoshima