Patents by Inventor Mitsuyasu KAWAGUCHI

Mitsuyasu KAWAGUCHI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FLUORESCENT PROBE FOR DETECTION OF ENPP ACTIVITY
    Publication number: 20230052551
    Abstract: Provided is a novel fluorescent probe. A compound of the following general formula (I) or a salt thereof.
    Type: Application
    Filed: June 8, 2020
    Publication date: February 16, 2023
    Applicants: THE UNIVERSITY OF TOKYO, PUBLIC UNIVERSITY CORPORATION NAGOYA CITY UNIVERSITY, RIKEN
    Inventors: Yasuteru URANO, Toru KOMATSU, Shingo SAKAMOTO, Hiroyuki NOJI, Hidehiko NAKAGAWA, Mitsuyasu KAWAGUCHI, Rikiya WATANABE
  • Fused pyrazole derivative having autotaxin inhibitory activity
    Patent number: 10189843
    Abstract: The present invention provides a compound of formula (1), wherein R1, R2, R3, R4a, R4b, R5a and R5b are as defined in the description, which has an autotaxin inhibitory activity, a pharmaceutical composition comprising the compound as an active ingredient, and a method of prevention or treatment of a disease involving autotaxin, which is characterized by administering the compound.
    Type: Grant
    Filed: February 26, 2015
    Date of Patent: January 29, 2019
    Assignees: THE UNIVERSITY OF TOKYO, TOHOKU UNIVERSITY, SHIONOGI & CO., LTD.
    Inventors: Tetsuo Nagano, Takayoshi Okabe, Hirotatsu Kojima, Mitsuyasu Kawaguchi, Osamu Nureki, Ryuichiro Ishitani, Hiroshi Nishimasu, Junken Aoki, Chiaki Fujikoshi, Manabu Katou, Masahide Odan, Nobuyuki Tanaka, Yusuke Tateno, Junji Yamane
  • Pyrimidinone derivative having autotaxin-inhibitory activity
    Patent number: 10183949
    Abstract: A compound according to any one of formula (Ia) to (Ic), or its pharmaceutically acceptable salt: wherein R1, R2, R3, R4a, R4c, R5 are as defined in the description.
    Type: Grant
    Filed: February 24, 2017
    Date of Patent: January 22, 2019
    Assignees: THE UNIVERSITY OF TOKYO, TOHOKU UNIVERSITY, SHIONOGI & CO., LTD.
    Inventors: Tetsuo Nagano, Takayoshi Okabe, Hirotatsu Kojima, Mitsuyasu Kawaguchi, Osamu Nureki, Ryuichiro Ishitani, Hiroshi Nishimasu, Junken Aoki, Nobuyuki Tanaka, Yasuhiko Kanda, Yoshiyuki Kioi, Yusuke Tateno, Shiro Kida, Junji Yamane
  • PYRIMIDINONE DERIVATIVE HAVING AUTOTAXIN-INHIBITORY ACTIVITY
    Publication number: 20170158704
    Abstract: A compound according to any one of formula (Ia) to (Ic), or its pharmaceutically acceptable salt: wherein R1, R2, R3, R4a, R4c, R5 are as defined in the description.
    Type: Application
    Filed: February 24, 2017
    Publication date: June 8, 2017
    Applicants: The University of Tokyo, TOHOKU UNIVERSITY, Shionogi & Co., Ltd.
    Inventors: Tetsuo NAGANO, Takayoshi OKABE, Hirotatsu KOJIMA, Mitsuyasu KAWAGUCHI, Osamu NUREKI, Ryuichiro ISHITANI, Hiroshi NISHIMASU, Junken AOKI, Nobuyuki TANAKA, Yasuhiko KANDA, Yoshiyuki KIOI, Yusuke TATENO, Shiro KIDA, Junji YAMANE
  • FUSED PYRAZOLE DERIVATIVE HAVING AUTOTAXIN INHIBITORY ACTIVITY
    Publication number: 20160376278
    Abstract: The present invention provides a compound of formula (1), wherein R1, R2, R3, R4a, R4b, R5a and R5b are as defined in the description, which has an autotaxin inhibitory activity, a pharmaceutical composition comprising the compound as an active ingredient, and a method of prevention or treatment of a disease involving autotaxin, which is characterized by administering the compound.
    Type: Application
    Filed: February 26, 2015
    Publication date: December 29, 2016
    Applicants: The University of Tokyo, TOHOKU UNIVERSITY, Shionogi & Co., Ltd.
    Inventors: Tetsuo NAGANO, Takayoshi OKABE, Hirotatsu KOJIMA, Mitsuyasu KAWAGUCHI, Osamu NUREKI, Ryuichiro ISHITANI, Hiroshi NISHIMASU, Junken AOKI, Chiaki FUJIKOSHI, Manabu KATOU, Masahide ODAN, Nobuyuki TANAKA, Yusuke TATENO, Junji YAMANE
  • 8-SUBSTITUTED IMIDAZOPYRIMIDINONE DERIVATIVE HAVING AUTOTAXIN INHIBITORY ACTIVITY
    Publication number: 20160002247
    Abstract: A compound of formula (I) wherein variables are as defined herein having an autotaxin inhibitory effect and a pharmaceutical composition comprising the same.
    Type: Application
    Filed: February 27, 2014
    Publication date: January 7, 2016
    Applicants: THE UNIVERSITY OF TOKYO, TOHOKU UNIVERSITY, Shionogi & Co., Ltd.
    Inventors: Tetsuo NAGANO, Takayoshi OKABE, Hirotatsu KOJIMA, Mitsuyasu KAWAGUCHI, Osamu NUREKI, Ryuichiro ISHITANI, Hiroshi NISHIMASU, Junken AOKI, Nobuyuki TANAKA, Chiaki FUJIKOSHI, Yusuke TATENO, Toshihiro WADA