Abstract: The present invention is to provide an agent for the prevention and depression of dry coughing caused by angiotensin converting enzyme inhibitors which comprises a thromboxane synthetase inhibitor or thromboxane receptor antagonist as the active ingredient. Administering the drug is effective in preventing and depressing dry coughing caused by angiotensin converting enzyme inhibitors. For example, the use of the drug in combination with ozagrel hydrochloride was found to be effective in significantly dry coughing in hypertonic patients suffering from dry coughing attributable to the administration of captopril.

Abstract: The invention relates to a method for improving inner ear microcirculation, which comprises administering an effective amount of a dihydropyridine compound of the general formula: ##STR1## wherein R.sup.1 is a nitrophenyl group; and R.sup.2, R.sup.3 and R.sup.4 each is a lower alkyl group, or a pharmaceutically acceptable salt thereof to a human or animal.

Abstract: A blood platelet-decreasing therapeutic drug comprising as an effective ingredient a 3(2H)-pyridazinone compound of the formula (I): ##STR1## wherein each of R.sup.1 and R.sup.2, which are independent of each other, is a hydrogen atom or a C.sub.1-4 alkyl group, and X is a chlorine atom or a bromine atom, or a pharmaceutically acceptable salt thereof.

Abstract: A method for treating edema or hypertension which comprises administering an effective amount of a quinazoline derivative of the general formula: ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 each is a hydrogen atom or a halogen atom or a pharmaceutically acceptable salt thereof to a human being in need of said treatment.

Abstract: The invention relates to a method for preventing and/or treating gout and hyperuricemia which comprises administering a uricosuric effective amount of a quinazoline derivative of the general formula: ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 each is a hydrogen atom or a halogen atom or a pharmaceutically acceptable salt thereof to a human being in need thereof.

Abstract: A cooling device for cooling parts in the proximity thereof consisting of a single pouch or a plurality of continuous pouches, wherein each pouch has at least one face thereof being made of water-permeable material and has sealed therein a hygroscopically swelling material. Due to such construction, the sealed material of the cooling device in an unemployed state, i.e., before being chilled in a freezer or freezing compartment, is not hygroscopically swelled and is not voluminous so that it can be decreased in weight by reducing the quantity of the sealed material which can improve the transportation efficiency, resulting in lowered transportation costs. Furthermore, the device can be easily and securely attached to any body part or object such as the shoulder of a man or a beer bottle.