Abstract: A stator (10) according to the present invention comprises: a yoke part (11) composed of a plurality of block bodies having an arc shape with a rectangular cross section; fixing members (12, 13) for disposing and fixing the plurality of block bodies in an annular shape; a plurality of teeth parts (14) erected on the peripheral surface of the yoke part; and a coil (15) wound around the plurality of teeth parts (14).

Abstract: It is intended to conveniently determine the pharmacokinetics of axitinib and to predict the therapeutic effect of axitinib. The present invention provides a method for determining the pharmacokinetics of axitinib, comprising the step of calculating a predicted pharmacokinetic parameter of axitinib using specific gene polymorphisms and background factors regarding a test subject.

Abstract: This invention is intended to accurately determine the presence or absence of a plurality of types of gene mutations in CALR or JAK2 among gene mutations related to myeloproliferative neoplasms. A CALR mutation probe reacts with any of the type 1, type 3, type 4, or the type 5 mutation related to myeloproliferative neoplasms and has a mismatch resulting from artificial deletion. Probes for JAK2 mutation encompass a V617F mutation probe and an exon 12 mutation probe.

Abstract: In the case of using a blocking nucleic acid to prevent non-specific hybridization of a target nucleic acid with a nucleic acid probe, further excellent efficiency of detecting the target nucleic acid is achieved. A buffer composition used in hybridization of a target nucleic acid with a nucleic acid probe, wherein the buffer composition for hybridization contains a blocking nucleic acid comprising a nucleotide sequence complementary to a region comprising at least a non-detection target nucleotide in a non-target nucleic acid, in a concentration of one or more times higher than the concentration of a nucleic acid in a nucleic acid mixture consisting of the target nucleic acid and the non-target nucleic acid.

Abstract: It is intended to conveniently determine the pharmacokinetics of axitinib and to predict the therapeutic effect of axitinib. The present invention provides a method for determining the pharmacokinetics of axitinib, comprising the step of calculating a predicted pharmacokinetic parameter of axitinib using specific gene polymorphisms and background factors regarding a test subject.

Abstract: The present invention easily identifies a genotype for gene mutations related to myeloproliferative neoplasms. The present invention comprises a mutant probe that specifically hybridizes with a gene mutation related to myeloproliferative neoplasms in JAK2, a mutant probe that specifically hybridizes with a gene mutation related to myeloproliferative neoplasms in CALR, and a mutant probe that specifically hybridizes with a gene mutation related to myeloproliferative neoplasms in MPL.

Abstract: In the case of using a blocking nucleic acid to prevent non-specific hybridization of a target nucleic acid with a nucleic acid probe, further excellent efficiency of detecting the target nucleic acid is achieved. A buffer composition used in hybridization of a target nucleic acid with a nucleic acid probe, wherein the buffer composition for hybridization contains a blocking nucleic acid comprising a nucleotide sequence complementary to a region comprising at least a non-detection target nucleotide in a non-target nucleic acid, in a concentration of one or more times higher than the concentration of a nucleic acid in a nucleic acid mixture consisting of the target nucleic acid and the non-target nucleic acid.

Abstract: An object of the present invention is to detect a mutation related to BCR-ABL inhibitor resistance with high accuracy for chronic myelogenous leukemia or the like. A method for detecting the mutation comprises the steps of: amplifying a region including a fusion site and a mutation site related to BCR-ABL inhibitor resistance contained in a BCR-ABL fusion gene using a biological sample collected from a subject; and genotyping of the mutation site related to BCR-ABL inhibitor resistance using nucleic acids amplified in the above step.

Abstract: A resonant motor system having a resonant circuit that includes magnetic coils and of capacitors, for generating an electric power when the resonant lot is rotated by an engine, a regenerating portion for the resonant motor, a motor driving portion, a motor control portion, and a capacitor portion for storing therein the electric power generated by the resonant motor when the resonant motor is regenerated, the resonant rotor being driven by the electric power stored in the capacitor portion when the engine is assisted by the resonant motor.

Abstract: A self-charging type electromagnetic retarder including a main portion having a stator yoke, a plurality of magnetic coils forming multi-phase connections, and a steel rotor, a control device, an electromagnetic retarder having a high revolution region, capacitor portion for storing excess electric power, a diode, and a low revolution region. The magnetic coils of each phase are connected with capacitors to form a resonance circuit. Transistors for the high revolution region are connected in series to each of the multi-phase connections. Transistors for the low revolution region are connected in series to each of the multi-phase connections through the capacitor portion and the diode. At the high revolution region, excess electric power obtained from the electric power generating type electromagnetic retarder portion is stored in the capacitor portion, and at the low revolution region, the magnetic coils are excited by the electric power stored in the capacitor portion.

Abstract: A resonant motor system having a resonant circuit that includes magnetic coils and of capacitors, for generating an electric power when the resonant lot is rotated by an engine, a regenerating portion for the resonant motor, a motor driving portion, a motor control portion, and a capacitor portion for storing therein the electric power generated by the resonant motor when the resonant motor is regenerated, the resonant rotor being driven by the electric power stored in the capacitor portion when the engine is assisted by the resonant motor.

Abstract: An electromagnetic coil for a retarder. A lead wire draw out portion includes a holder having a bottom portion through which a lead wire of the electromagnetic coil is passed and a reservoir to be filled with an adhesive.

Abstract: An electromagnetic retarder includes a stator yoke, a plurality of magnetic coils, and a steel rotor; a control device; a driving device for a high revolution region having transistors; and a driving device for a low revolution region having a battery, a diode for inhibiting reverse current, and transistors. The magnetic coils of each phase are coupled with capacitors so as to form a resonance circuit. Each of the transistors for the high revolution region is coupled in series to each of the multi-phase connections. Each of the transistors for the low revolution region is connected in series to each of the multi-phase connections through the battery and the diode. At the high revolution region, the magnetic coils are excited by an electric power obtained from a braking energy, and at the low revolution region, the magnetic coils are excited by an electric power obtained from the battery.

Abstract: An electromagnetic type retarder includes a stator having spaced, circularly arranged magnetic coils forming multi-phase connections and a steel rotor surrounding the stator and rotated according to the rotation of a tire; a control device; and a driving device including at least two transistors opened and closed by a drive pulse from the control device, respectively. The multi phase connections are formed by the magnetic coils, the magnetic coils of each phase are connected with capacitors to form a resonance circuit, respectively, and each of the transistors is connected in series to at least two phase connections. The revolution speed of a rotary magnetic field induced in he magnetic coils by the rotation of the steel rotor is set smaller than the revolution speed of the steel rotor. A braking torque is controlled by turning ON and OFF the transistor inserted in one phase connection.

Abstract: An electromagnetic type retarder comprises a main portion consisting of a stator having a plurality of magnetic coils arranged along a circle and spaced apart from one another, and of a steel rotor surrounding the stator and rotated according to the rotation of a tire; a driving device for the main portion to be controlled by an operation signal; and an output terminal for an additional device; the magnetic coils consisting of three-phase or two-phase connections. Each of the magnetic coils is connected with a capacitor so as to form a resonance circuit, respectively. The driving device has transistors connected in series to each of the connections and controlled so as to be opened and closed by the operation signal. The revolution speed of a rotary magnetic field generated by AC voltage induced in the magnetic coils forming the resonance circuits by the rotation of the steel rotor is set smaller than the revolution speed of the steel rotor.

Abstract: An electric heating device suitable for heating an electric vehicle and having a novel structure is provided. The electric heating device includes: an electric motor that includes a stator having a plurality of stator coils arranged along the circumferential direction to generate a rotating magnetic field and a disk-shaped rotor that includes a plurality of one-turn coils disposed correspondingly to the stator coils and a soft magnetic metal plate supporting the one-turn coils; and a fan secured to the soft magnetic metal plate on a side thereof opposite from the one-turn coils and including a vane wheel that has a plurality of vanes and rotates integrally with the rotor.

Abstract: An electromagnetic type retarder comprises a main portion consisting of a stator having a plurality of magnetic coils arranged along a circle and spaced apart from one another, and of a steel rotor surrounding the stator and rotated according to the rotation of a tire; a driving device for the main portion to be controlled by an operation signal; and an output terminal for an additional device; the magnetic coils consisting of three-phase or two-phase connections. Each of the magnetic coils is connected with a capacitor so as to form a resonance circuit, respectively. The driving device has transistors connected in series to each of the connections and controlled so as to be opened and closed by the operation signal. The revolution speed of a rotary magnetic field generated by AC voltage induced in the magnetic coils forming the resonance circuits by the rotation of the steel rotor is set smaller than the revolution speed of the steel rotor.