Patents by Inventor Mitsuyoshi Toyosato

Mitsuyoshi Toyosato has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant lysophosphatidic acid phosphatase
    Patent number: 7109012
    Abstract: An object of the present invention is to provide a recombinant LPA phosphatase capable of specifically hydrolyzing LPA, which is useful for elucidation of the metabolism pathway of LPA, and also for diagnosis and treatment of various diseases with which LPA is associated; a method capable of simply and inexpensively determining LPA associated with various diseases; and a kit for determination suitable for the method. The present invention has succeeded in purifying the LPA phosphatase using bovine brain as raw material, and further in cloning human LPA phosphatase gene.
    Type: Grant
    Filed: August 7, 2002
    Date of Patent: September 19, 2006
    Assignee: Azwell Inc.
    Inventors: Tadaomi Takenawa, Masami Hiroyama, Tatsuya Kishimoto, Masahiro Yamaguchi, Mitsuyoshi Toyosato, Kouji Mizuno
  • Recombinant lysophosphatidic acid phosphatase
    Publication number: 20030104600
    Abstract: An object of the present invention is to provide a recombinant LPA phosphatase capable of specifically hydrolyzing LPA, which is useful for elucidation of the metabolism pathway of LPA, and also for diagnosis and treatment of various diseases with which LPA is associated; a method capable of simply and inexpensively determining LPA associated with various diseases; and a kit for determination suitable for the method. The present invention has succeeded in purifying the LPA phosphatase using bovine brain as a raw material, and further in cloning human LPA phosphatase gene.
    Type: Application
    Filed: August 7, 2002
    Publication date: June 5, 2003
    Applicant: Azwell Inc.
    Inventors: Tadaomi Takenawa, Masami Hiroyama, Tatsuya Kishimoto, Masahiro Yamaguchi, Mitsuyoshi Toyosato, Kouji Mizuno
  • Recombinant lysophosphatidic acid phosphatase
    Patent number: 6472193
    Abstract: An object of the present invention is to provide a recombinant LPA phosphates capable of specifically hydrolyzing LPA, which is useful for elucidation of the metabolic pathway of LPA, and also for diagnosis and treatment of various diseases with which LPA is associated. The present invention also provides for a method capable of simply and inexpensively determining LPA associated with various diseases. The present invention also provides for a kit for determination suitable for the method. The present invention has succeeded in purifying the LPA phosphatase using bovine brain as a raw material, and further in cloning human LPA phosphatase gene.
    Type: Grant
    Filed: September 11, 2000
    Date of Patent: October 29, 2002
    Assignee: Azwell Inc.
    Inventors: Tadaomi Takenawa, Masami Hiroyama, Tatsuya Kishimoto, Masahiro Yamaguchi, Mitsuyoshi Toyosato, Kouji Mizuno