Patents by Inventor Miwa Hasegawa
Miwa Hasegawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 7267750Abstract: A biosensor comprising: an electrically insulating base plate; an electrode system comprising a working electrode and a counter electrode formed on the base plate; a cover member which is joined to the base plate to form a sample solution supply pathway for supplying a sample solution to the electrode system between the cover member and the base plate; and a reagent system comprising at least an oxidoreductase and an electron mediator disposed in the sample solution supply pathway, wherein the electron mediator is provided on the base plate and the oxidoreductase is provided on the cover member such that the electron mediator and the oxidoreductase are not in contact with each other.Type: GrantFiled: January 10, 2002Date of Patent: September 11, 2007Assignee: Matsushita Electric Industrial Co., Ltd.Inventors: Motokazu Watanabe, Tomohiro Yamamoto, Miwa Hasegawa, Shin Ikeda, Shiro Nankai
-
Patent number: 7056425Abstract: To provide an improved biosensor which allows easy addition of whole blood to the sensor and rapid supply of the added whole blood to a filter even in the case of collecting blood by fingertip centesis for measurement, a second air aperture is provided in a sample solution supply pathway including an electrode system and a reaction layer and communicating with a first air aperture on the terminal end side.Type: GrantFiled: November 12, 2002Date of Patent: June 6, 2006Assignee: Matsushita Electric Industrial Co., Ltd.Inventors: Miwa Hasegawa, Tomohiro Yamamoto, Shin Ikeda, Toshihiko Yoshioka
-
Patent number: 6977032Abstract: A biosensor including an insulating base plate, an electrode system, a cover for covering the insulating base plate, at least one reaction layer, a sample solution supply pathway communicating with an air aperture at a terminal end side, a sample solution supply part and a filter provided between the sample solution supply pathway and the sample solution supply part to filter hemocytes, an end face and a top face of a primary portion of the filter are exposed and the sample solution supply part is provided adjacently to the primary side portion so as to provide an improved biosensor which allows easy addition of whole blood to the sensor and rapid supply of the added whole blood to a filter even in the case of collecting blood by fingertip centesis for measurement.Type: GrantFiled: November 12, 2002Date of Patent: December 20, 2005Assignee: Matsushita Electric Industrial Co., Ltd.Inventors: Miwa Hasegawa, Tomohiro Yamamoto, Shin Ikeda, Toshihiko Yoshioka
-
Patent number: 6966977Abstract: A sensor including an insulating base plate; an electrode system, provided on the base plate, having a measuring electrode and a counter electrode; a reaction layer including at least an oxidoreductase and an electron mediator; a sample solution supply pathway including the electrode system and the reaction layer; and a sample supply unit, wherein the sensor is so structured that, between the sample supply unit and the sample solution supply pathway, there is provided a filter having a function to filter out hemocytes and having a cross-sectional area larger than an opening of the sample solution supply pathway, and that plasma of a blood with hemocytes thereof having been filtered out is sucked into the inside of the sample solution supply pathway owing to capillary phenomena.Type: GrantFiled: January 24, 2003Date of Patent: November 22, 2005Assignee: Matsushita Electric Industrial Co., Ltd.Inventors: Miwa Hasegawa, Tomohiro Yamamoto, Motokazu Watanabe, Shin Ikeda, Shiro Nankai
-
Publication number: 20050072670Abstract: In order to provide a biosensor with high accuracy and excellent response where plasma obtained by filtration of blood rapidly arrives at an electrode system, in a biosensor comprising: an insulating base plate; an electrode system having a working electrode and a counter electrode which are provided on the base plate; a reaction layer including at least oxidoreductase and an electron mediator; a sample solution supply pathway which includes the electrode system and the reaction layer and has an inlet and an air aperture; a sample solution supply part for introducing a sample solution, which is in position apart from the sample solution supply pathway; and a first filter which is disposed between the sample solution supply pathway and the sample solution supply part for filtering the sample solution, where the filtrate filtered with the first filter is supplied into the sample solution supply pathway due to capillary action, the direction in which the sample solution passes through the first filter and the diType: ApplicationFiled: December 27, 2002Publication date: April 7, 2005Inventors: Miwa Hasegawa, Tomohiro Yamamoto, Motokazu Watanabe, Takahiro Nakaminami, Shin Ikeda, Toshihiko Yoshioka, Shiro Nankai
-
Patent number: 6821410Abstract: Disclosed is a highly responsive biosensor comprising a cholesterol-oxidizing enzyme and cholesterol esterase. The biosensor comprises: an electrically insulating base plate; an electrode system including a working electrode and a counter electrode formed on the base plate; a cover member joined with the base plate to define a sample supply pathway through which a sample solution is introduced from a sample supply port to the electrode system, the sample supply pathway being formed between the cover member and the base plate; and a reagent layer formed in the sample supply pathway, wherein the reagent layer contains a cholesterol-oxidizing enzyme, cholesterol esterase, an electron mediator, and a buffer having a buffering capacity in an acidic pH range.Type: GrantFiled: March 1, 2002Date of Patent: November 23, 2004Assignee: Matsushita Electric Industrial Co., Ltd.Inventors: Motokazu Watanabe, Miwa Hasegawa, Tomohiro Yamamoto, Toshihiko Yoshioka, Shiro Nankai
-
Patent number: 6776888Abstract: The present invention provides a biosensor that enables highly-accurate measurement of a sample solution including a solid component like hemocytes and has a little variation in response. The biosensor includes: an insulating base plate, an electrode system having at least a working electrode and a counter electrode provided on the base plate, a cover member that is combined with the base plate to define a sample solution supply pathway for leading a sample solution from a sample supply unit to the electrode system, a reaction reagent system including at least an oxidation-reduction enzyme and an electron mediator, and a filter disposed between the electrode system and the sample supply unit in the sample solution supply pathway. The biosensor has a space that encircles surface of the filter in an area from one end of the filter close to the sample supply unit to the other end of the filter close to the electrode system.Type: GrantFiled: March 26, 2002Date of Patent: August 17, 2004Assignee: Matsushita Electric Industrial Co., Ltd.Inventors: Tomohiro Yamamoto, Miwa Hasegawa, Motokazu Watanabe, Shin Ikeda, Shiro Nankai
-
Publication number: 20040096928Abstract: In a biosensor comprising an insulating base plate, an electrode system including a measuring electrode and a counter electrode provided on said base plate, a cover for covering said insulating base plate, at least one reaction layer containing oxidoreductase and/or an electron mediator, a sample solution supply pathway including said electrode system and said reaction layer and communicating with an air aperture at a terminal end side, a sample solution supply part and a filter provided between said sample solution supply pathway and said sample solution supply part to filter hemocytes, an end face and a top face of a primary portion of the filter are exposed and the sample solution supply part is provided adjacently to the primary side portion so as to provide an improved biosensor which allows easy addition of whole blood to the sensor and rapid supply of the added whole blood to a filter even in the case of collecting blood by fingertip centesis for measurement.Type: ApplicationFiled: September 17, 2003Publication date: May 20, 2004Inventors: Miwa Hasegawa, Tomohiro Yamamoto, Shin Ikeda, Toshihiko Yoshioka
-
Publication number: 20040082045Abstract: To provide an improved biosensor which allows easy addition of whole blood to the sensor and rapid supply of the added whole blood to a filter even in the case of collecting blood by fingertip centesis for measurement, a second air aperture is provided in a sample solution supply pathway including an electrode system and a reaction layer and communicating with a first air aperture on the terminal end side.Type: ApplicationFiled: September 2, 2003Publication date: April 29, 2004Inventors: Miwa Hasegawa, Tomohiro Yamamoto, Shin Ikeda, Toshihiko Yoshioka
-
Publication number: 20040069628Abstract: A biosensor comprising: an electrically insulating base plate; an electrode system comprising a working electrode and a counter electrode formed on the base plate; a cover member which is joined to the base plate to form a sample solution supply pathway for supplying a sample solution to the electrode system between the cover member and the base plate; and a reagent system comprising at least an oxidoreductase and an electron mediator disposed in the sample solution supply pathway, wherein the electron mediator is provided on the base plate and the oxidoreductase is provided on the cover member such that the electron mediator and the oxidoreductase are not in contact with each other.Type: ApplicationFiled: July 17, 2003Publication date: April 15, 2004Inventors: Motokazu Watanabe, Tomohiro Yamamoto, Miwa Hasegawa, Shin Ikeda, Shiro Nankai
-
Patent number: 6719887Abstract: A biosensor includes: an insulating base plate; an electrode system which is provided on the base plate and has a measurement electrode and a counter electrode; a reaction layer including at least oxidoreductase and an electron mediator; a sample solution supply pathway which includes the electrode system and the reaction layer and has an air aperture on the termination side thereof; a sample supply portion; and a filter which is disposed between the sample solution supply pathway and the sample supply portion and filters hemocytes, where plasma with the hemocytes therein filtered with the filter is sucked into the sample solution supply pathway due to capillarity, the central part of a secondary side portion of the filter is protruded into the sample solution supply pathway more than both the right and left ends thereof.Type: GrantFiled: September 17, 2002Date of Patent: April 13, 2004Assignee: Matsushita Electric Industrial Co., Ltd.Inventors: Miwa Hasegawa, Motokazu Watanabe, Tomohiro Yamamoto, Shin Ikeda, Shiro Nankai
-
Publication number: 20040055885Abstract: A biosensor in accordance with the present invention comprises: an electrically insulating base plate; an electrode system comprising at least a measuring electrode and a counter electrode formed on the base plate; a cover member which is joined to the base plate to form a sample solution supply pathway for supplying a sample solution to the electrode system between the cover member and the base plate; and a reaction reagent carried at a position which is exposed to the sample solution supply pathway.Type: ApplicationFiled: July 24, 2003Publication date: March 25, 2004Inventors: Tomohiro Yamamoto, Miwa Hasegawa, Yoshiko Miyamoto, Toshihiko Yoshioka
-
Patent number: 6706232Abstract: There is provided a cholesterol sensor with high-accuracy and excellent response, whose object to be measured is whole blood, where plasma with hemocytes therein filtered can rapidly reach an electrode system. In a biosensor where plasma with hemocytes therein filtered with a filter is sucked into a sample solution supply pathway due to capillarity, there are formed: a first pressing part for holding a primary side portion of the filter from the bottom; a second pressing part for holding a secondary side portion of the filter from the top and the bottom; a third pressing part for holding the central portion of the filter from the top; and a void for surrounding the filter between the second pressing part and third pressing part.Type: GrantFiled: March 4, 2003Date of Patent: March 16, 2004Assignee: Matsushita Electric Industrial Co., Ltd.Inventors: Miwa Hasegawa, Tomohiro Yamamoto, Motokazu Watanabe, Takahiro Nakaminami, Shin Ikeda, Toshihiko Yoshioka, Shiro Nankai
-
Publication number: 20040020777Abstract: In a biosensor comprising an electrically insulating base plate, an electrode system including a working electrode and a counter electrode formed on the base plate, and a reaction layer formed on or in the vicinity of the electrode system, at least surface of the reaction layer is made porous, so as to provide a biosensor of good response characteristic in which a reaction layer containing an enzyme dissolves quickly into a small amount of a sample solution and the enzyme reaction is effectively utilized.Type: ApplicationFiled: June 3, 2003Publication date: February 5, 2004Inventors: Yoshiko Miyamoto, Tomohiro Yamamoto, Miwa Hasegawa, Toshihiko Yoshioka
-
Publication number: 20030183519Abstract: There is provided a cholesterol sensor with high-accuracy and excellent response, whose object to be measured is whole blood, where plasma with hemocytes therein filtered can rapidly reach an electrode system. In a biosensor where plasma with hemocytes therein filtered with a filter is sucked into a sample solution supply pathway due to capillarity, there are formed: a first pressing part for holding a primary side portion of the filter from the bottom; a second pressing part for holding a secondary side portion of the filter from the top and the bottom; a third pressing part for holding the central portion of the filter from the top; and a void for surrounding the filter between the second pressing part and third pressing part.Type: ApplicationFiled: March 4, 2003Publication date: October 2, 2003Inventors: Miwa Hasegawa, Tomohiro Yamamoto, Motokazu Watanabe, Takahiro Nakaminami, Shin Ikeda, Toshihiko Yoshioka, Shiro Nankai
-
Publication number: 20030132110Abstract: The present invention provides a so improved biosensor that a whole blood is allowed to be an object to be measured, and that plasma of a blood, with hemocytes thereof having been filtered out, is allowed to quickly reach an electrode system.Type: ApplicationFiled: January 24, 2003Publication date: July 17, 2003Applicant: Matsushita Electric Industrial Co., Ltd.Inventors: Miwa Hasegawa, Tomohiro Yamamoto, Motokazu Watanabe, Shin Ikeda, Shiro Nankai
-
Publication number: 20030098234Abstract: In order to provide a cholesterol sensor capable of measuring whole blood with high accuracy and excellent response, where plasma with hemocytes therein filtered promptly reaches an electrode system, in a biosensor comprising: an insulating base plate; an electrode system which is provided on the base plate and has a measurement electrode and a counter electrode; a reaction layer including at least oxidoreductase and an electron mediator; a sample solution supply pathway which includes the electrode system and the reaction layer and has an air aperture on the termination side thereof; a sample supply portion; and a filter which is disposed between the sample solution supply pathway and the sample supply portion and filters hemocytes, where plasma with the hemocytes therein filtered with the filter is sucked into the sample solution supply pathway due to capillarity, the central part of a secondary side portion of the filter is protruded into the sample solution supply pathway more than both the right and leftType: ApplicationFiled: September 17, 2002Publication date: May 29, 2003Inventors: Miwa Hasegawa, Motokazu Watanabe, Tomohiro Yamamoto, Shin Ikeda, Shiro Nankai
-
Publication number: 20020148726Abstract: The present invention provides a biosensor that enables highly-accurate measurement of a sample solution including a solid component like hemocytes and has a little variation in response. The biosensor includes: an insulating base plate, an electrode system having at least a working electrode and a counter electrode provided on the base plate, a cover member that is combined with the base plate to define a sample solution supply pathway for leading a sample solution from a sample supply unit to the electrode system, a reaction reagent system including at least an oxidation-reduction enzyme and an electron mediator, and a filter disposed between the electrode system and the sample supply unit in the sample solution supply pathway. The biosensor has a space that encircles surface of the filter in an area from one end of the filter close to the sample supply unit to the other end of the filter close to the electrode system.Type: ApplicationFiled: March 26, 2002Publication date: October 17, 2002Inventors: Tomohiro Yamamoto, Miwa Hasegawa, Motokazu Watanabe, Shin Ikeda, Shiro Nankai
-
Publication number: 20020134676Abstract: Disclosed is a highly responsive biosensor comprising a cholesterol-oxidizing enzyme and cholesterol esterase. The biosensor comprises: an electrically insulating base plate; an electrode system including a working electrode and a counter electrode formed on the base plate; a cover member joined with the base plate to define a sample supply pathway through which a sample solution is introduced from a sample supply port to the electrode system, the sample supply pathway being formed between the cover member and the base plate; and a reagent layer formed in the sample supply pathway, wherein the reagent layer contains a cholesterol-oxidizing enzyme, cholesterol esterase, an electron mediator, and a buffer having a buffering capacity in an acidic pH range.Type: ApplicationFiled: March 1, 2002Publication date: September 26, 2002Applicant: Matsushita Electric Industrial Co., Ltd.Inventors: Motokazu Watanabe, Miwa Hasegawa, Tomohiro Yamamoto, Toshihiko Yoshioka, Shiro Nankai
-
Patent number: RE39390Abstract: There is provided a cholesterol sensor with high-accuracy and excellent response, whose object to be measured is whole blood, where plasma with which is obtained by filtering out hemocytes therein filtered in blood can rapidly reach an electrode system. In a biosensor where plasma with which is obtained by filtering out hemocytes therein filtered with by a filter is sucked into a sample solution supply pathway due to capillarity, there are formed: a first pressing part for holding a primary side portion of the filter from the bottom; a second pressing part for holding a secondary side portion of the filter from the top and the bottom; a third pressing part for holding the central portion of the filter from the top; and a void for surrounding the filter between the second pressing part and third pressing part.Type: GrantFiled: May 17, 2002Date of Patent: November 14, 2006Assignee: Matsushita Electric Industrial Co., Ltd.Inventors: Miwa Hasegawa, Tomohiro Yamamoto, Motokazu Watanabe, Takahiro Nakaminami, Shin Ikeda, Toshihiko Yoshioka, Shiro Nankai