Publication number: 20120046451
Abstract: It is intended to clarify a molecule which is available as a target in treating or diagnosing cancer and utilize the molecule in the medical field or the research field. By treating IgSF4, which has been identified as a molecule specifically expressed in lung cancer cells, with an antibody, and ADCC activity is exerted. Based on this finding, an anti-IgSF4 antibody is provided as a means efficacious in treating cancer, etc.
Type:
Application
Filed:
September 21, 2011
Publication date:
February 23, 2012
Applicants:
Institute for Antibodies Co., Ltd.
Inventors:
Yoshikazu Kurosawa, Yasushi Akahori, Nobuhiro Takahashi, Atsushi Sugioka, Nobuhiro Hayashi, Akihiko Takasaki, Kazuhiro Suzuki, Miwa Morita, Gene Kurosawa, Sari Fujiyama, Susumu Tsutsumi, Keiko Ogawa, Kazuki Matsuda, Chiho Muramatsu, Yoshitaka Iba, Mariko Sumitomo, Masachika Azuma, Yoshinori Ukai, Kazuhiro Morishita