Patents by Inventor Miyuki Uni

Miyuki Uni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tricyclic compound and JAK inhibitor
    Patent number: 10385052
    Abstract: Novel tricyclic compounds which have JAK inhibitory activities are useful for prevention, treatment or improvement of autoimmune diseases, inflammatory diseases and allergic diseases are provided. Novel tricyclic compound represented by the formula (I), the formula (II) or the formula (III) (wherein: each of A1, A2 and A3 is a cyclohexane-1,4-diyl group or the like; each of L1, L2 and L3 is a methylene group or the like; each of X1 and X3 is O or NH; each of R1 and R3 is a cyano C1-6 haloalkyl group or the like; and R2 is an aromatic heterocyclic group), a tautomer or pharmaceutically acceptable salt of the compound or a solvate thereof.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: August 20, 2019
    Assignee: Nissan Chemical Corporation
    Inventors: Tsuneo Watanabe, Keiji Takahashi, Keishi Hayashi, Takanori Nakamura, Masataka Minami, Kazunori Kurihara, Akio Yamamoto, Takuya Nishimura, Miyuki Uni, Toshihiko Kamiyama, Shunsuke Iwamoto
  • TRICYCLIC COMPOUND AND JAK INHIBITOR
    Publication number: 20180099966
    Abstract: Novel tricyclic compounds which have JAK inhibitory activities are useful for prevention, treatment or improvement of autoimmune diseases, inflammatory diseases and allergic diseases are provided. Novel tricyclic compound represented by the formula (I), the formula (II) or the formula (III) (wherein: each of A1, A2 and A3 is a cyclohexane-1,4-diyl group or the like; each of L1, L2 and L3 is a methylene group or the like; each of X1 and X3 is 0 or NH; each of R1 and R3 is a cyano C1-6 haloalkyl group or the like; and R2 is an aromatic heterocyclic group), a tautomer or pharmaceutically acceptable salt of the compound or a solvate thereof.
    Type: Application
    Filed: December 13, 2017
    Publication date: April 12, 2018
    Applicant: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Tsuneo Watanabe, Keiji Takahashi, Keishi Hayashi, Takanori Nakamura, Masataka Minami, Kazunori Kurihara, Akio Yamamoto, Takuya Nishimura, Miyuki Uni, Toshihiko Kamiyama, Shunsuke Iwamoto
  • Tricyclic compound and JAK inhibitor
    Patent number: 9890165
    Abstract: Novel tricyclic compounds which have JAK inhibitory activities are useful for prevention, treatment or improvement of autoimmune diseases, inflammatory diseases and allergic diseases are provided. Novel tricyclic compound represented by the formula (I), the formula (II) or the formula (III) (wherein: each of A1, A2 and A3 is a cyclohexane-1,4-diyl group or the like; each of L1, L2 and L3 is a methylene group or the like; each of X1 and X3 is O or NH; each of R1 and R3 is a cyano C1-6 haloalkyl group or the like; and R2 is an aromatic heterocyclic group), a tautomer or pharmaceutically acceptable salt of the compound or a solvate thereof.
    Type: Grant
    Filed: May 11, 2015
    Date of Patent: February 13, 2018
    Assignee: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Tsuneo Watanabe, Keiji Takahashi, Keishi Hayashi, Takanori Nakamura, Masataka Minami, Kazunori Kurihara, Akio Yamamoto, Takuya Nishimura, Miyuki Uni, Toshihiko Kamiyama, Shunsuke Iwamoto
  • TRICYCLIC COMPOUND AND JAK INHIBITOR
    Publication number: 20170044161
    Abstract: Novel tricyclic compounds which have JAK inhibitory activities are useful for prevention, treatment or improvement of autoimmune diseases, inflammatory diseases and allergic diseases are provided. Novel tricyclic compound represented by the formula (I), the formula (II) or the formula (III) (wherein each of A1, A2 and A3 is a cyclohexane-1,4-diyl group or the like; each of L1, L2 and L3 is a methylene group or the like: each of X1 and X3 is O or NH; each of R1 and R3 is a cyano C1-6 haloalkyl group or the like; and R2 is an aromatic heterocyclic group), a tautomer or pharmaceutically acceptable salt of the compound or a solvate thereof.
    Type: Application
    Filed: May 11, 2015
    Publication date: February 16, 2017
    Applicant: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Tsuneo WATANABE, Keiji TAKAHASHI, Keishi HAYASHI, Takanori NAKAMURA, Masataka MINAMI, Kazunori KURIHARA, Akio YAMAMOTO, Takuya NISHIMURA, Miyuki UNI, Toshihiko KAMIYAMA, Shunsuke IWAMOTO
  • Substituted pyrrolo[3?,2?:5,6]pyrido[4,3-d]pyrimidines and JAK inhibitors comprising the same
    Patent number: 9556187
    Abstract: This disclosure relates to novel tricyclic pyrimidine compounds and tricyclic pyridine compounds having JAK inhibitory activities. A tricyclic heterocyclic compound represented by the formula (Ib), wherein the rings Ab and Bb, Xb, Yb, R1b, R2b, R3b, L1b, L2b, L3b and nb are as defined in the specification.
    Type: Grant
    Filed: October 2, 2015
    Date of Patent: January 31, 2017
    Assignee: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Keishi Hayashi, Tsuneo Watanabe, Koji Toyama, Junji Kamon, Masataka Minami, Miyuki Uni, Mariko Nasu
  • TRICYCLIC HETEROCYCLIC COMPOUNDS AND JAK INHIBITORS
    Publication number: 20160102102
    Abstract: This disclosure relates to novel tricyclic pyrimidine compounds and tricyclic pyridine compounds having JAK inhibitory activities. A tricyclic heterocyclic compound represented by the formula (Ib), wherein the rings Ab and Bb, Xb, Yb, R1b, R2b, R3b, L1b, L2b, L3b and nb are as defined in the specification.
    Type: Application
    Filed: October 2, 2015
    Publication date: April 14, 2016
    Applicant: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Keishi HAYASHI, Tsuneo Watanabe, Koji Toyama, Junji Kamon, Masataka Minami, Miyuki Uni, Mariko Nasu
  • Substituted pyrrolo[2,3-h][1,6]naphthyridines and compositions thereof as JAK inhibitors
    Patent number: 9216999
    Abstract: Novel tricyclic pyrimidine compounds and tricyclic pyridine compounds having JAK inhibitory activities are provided. A tricyclic heterocyclic compound represented by the formula (Ia): wherein the rings Aa and Ba, Xa, Ya, R1a, R2a, R3a, L1a L2a, L3a and na are as defined in the description.
    Type: Grant
    Filed: August 10, 2012
    Date of Patent: December 22, 2015
    Assignee: Nissan Chemical Industries, Ltd.
    Inventors: Keishi Hayashi, Tsuneo Watanabe, Koji Toyama, Junji Kamon, Masataka Minami, Miyuki Uni, Mariko Nasu
  • TRICYCLIC HETEROCYCLIC COMPOUNDS AND JAK INHIBITORS
    Publication number: 20140200344
    Abstract: Novel tricyclic pyrimidine compounds and tricyclic pyridine compounds having JAK inhibitory activities are provided. A tricyclic heterocyclic compound represented by the formula (Ia): wherein the rings Aa and Ba, Xa, Ya, R1a, R2a, R3a, L1a L2a, L3a and na are as defined in the description.
    Type: Application
    Filed: August 10, 2012
    Publication date: July 17, 2014
    Applicant: Nissan Chemical Industries, Ltd.
    Inventors: Keishi Hayashi, Tsuneo Watanabe, Koji Toyama, Junji Kamon, Masataka Minami, Miyuki Uni, Mariko Nasu