Abstract: An RNA of the present invention is an RNA containing a 5? cap structure and a coding region having a 5? initiation codon and a 3? stop codon on both ends of the coding region, the RNA having a nucleoside compound introduced at a site selected from among the 5? cap structure and 10 bases from a 5? end of the RNA, wherein the nucleoside compound is such that a group is attached to (i) a carbon atom at position 8 of a purine nucleus or (ii) a carbon atom at position 5 or 6 of a pyrimidine nucleus, the group being represented by formula (I): A-X?X-#??(I) where A represents an aryl group or a heteroaryl group, # represents a site where the group represented by the formula (I) is attached to the carbon atom at the position 8 of the purine nucleus or the carbon atom at the position 5 or 6 of the pyrimidine nucleus, and two Xs, which are identical to or different from each other, each represents a nitrogen atom or CH whose H may be substituted by alkyl.

Abstract: An RNA of the present invention is an RNA containing a 5? cap structure and a coding region having a 5? initiation codon and a 3? stop codon on both ends of the coding region, the RNA having a nucleoside compound introduced at a site selected from among the 5? cap structure and 10 bases from a 5? end of the RNA, wherein the nucleoside compound is such that a group is attached to (i) a carbon atom at position 8 of a purine nucleus or (ii) a carbon atom at position 5 or 6 of a pyrimidine nucleus, the group being represented by formula (I): A-X?X-#??(I) where A represents an aryl group or a heteroaryl group, # represents a site where the group represented by the formula (I) is attached to the carbon atom at the position 8 of the purine nucleus or the carbon atom at the position 5 or 6 of the pyrimidine nucleus, and two Xs, which are identical to or different from each other, each represents a nitrogen atom or CH whose H may be substituted by alkyl.

Abstract: This invention provides a novel bioimaging technique that can achieve a deep observation depth and a novel method for marking a lesion that allows clear recognition of the lesion from outside a living body. This invention also provides a bioimaging marker comprising a fluorescent material obtained by doping a ceramic with rare earths and the like and a bioimaging technique comprising detecting near-infrared fluorescence that can sufficiently penetrate a living body generated upon excitation of the marker with near-infrared excitation light.

Abstract: A ligand DNA including a probe portion having a sequence that is complementary to a target DNA to be detected in a sample DNA, and a probe portion having a base sequence that is complementary to a base sequence of a marker DNA 2 in a conjugate DNA 10 is formed, and the sample DNA and the ligand DNA are combined to form a DNA complex, and further, the DNA complex is made to perform electrophoresis in the conjugate DNA. Therefore, it is possible to provide a DNA separation detection method which can appropriately separate the sample DNA and deal with various kinds of target sample DNAs in short time, without the necessity of searching for an optimum electrophoresis condition by complicatedly combining the amount of a bonding control agent to be contained in the conjugate DNA, the viscosity of linear polymer, the amount of the sample DNA, the amount of the conjugate DNA, and the like, for each DNA sequence as a detection target, when separating the sample DNA by electrophoresis.

Abstract: An object of the present invention is to provide products composed of a biodegradable raw material(s). The present invention provides a biodegradable oil absorbing film containing polyhydroxyalkanoate.

Abstract: There are provided a gene detection method and an apparatus thereof, for detecting a gene having a specific sequence in a specimen with high sensitivity.

Abstract: A ligand DNA including a probe portion having a sequence that is complementary to a target DNA to be detected in a sample DNA, and a probe portion having a base sequence that is complementary to a base sequence of a marker DNA 2 in a conjugate DNA 10 is formed, and the sample DNA and the ligand DNA are combined to form a DNA complex, and further, the DNA complex is made to perform electrophoresis in the conjugate DNA. Therefore, it is possible to provide a DNA separation detection method which can appropriately separate the sample DNA and deal with various kinds of target sample DNAs in short time, without the necessity of searching for an optimum electrophoresis condition by complicatedly combining the amount of a bonding control agent to be contained in the conjugate DNA, the viscosity of linear polymer, the amount of the sample DNA, the amount of the conjugate DNA, and the like, for each DNA sequence as a detection target, when separating the sample DNA by electrophoresis.

Abstract: The method of sequential continuous-casting of the different grade of steel according to the present invention comprises the steps of: stopping the pouring of a first grade of molten steel into a mold and the drawing of cast slab; immersing a columnar steel stock being circular or polygonal in cross section and equipped with guiding jigs into the substantially center portion of the first grade of molten steel in said mold; forming a solidified phase around said cooling material; and merging said solidified phase in a solidified shell developed from the wall of the mold to form a solidified layer shutting the upper portion off the lower portion of the first grade of molten steel.