Abstract: The present disclosure relates to compositions comprising dietary fibers. For example, in some embodiments, the composition comprises two or more fibers (e.g., fibers such as beta-glucan, wheat dextrin, inulin, pectin, psyllium, or potato starch) each present in amount of about 40% to about 60% w/w of the composition. In some embodiments, the composition further includes a sweetener and/or a flavoring agent. Such compositions are useful in the treatment or improvement of gastrointestinal diseases.

Abstract: This disclosure relates to topical personal care compositions comprising one or more of a yeast component; a Bacillaceae extract; and 13-methyltetradecanoate; and B) one or more of: a phytochemical; an organic acid; and an antimicrobial peptide. In some embodiments, a composition as described herein can include a yeast component present in an amount of at least about 0.5% w/w of the composition; caffeine present in an amount of about 0.05% to about 5% w/w of the composition; a lemon grass extract present in an amount of at least about 0.01% to about 5% w/w of the composition; and an citrus fruit extract present in an amount of at least about 0.01% to about 5% w/w of the composition. In some embodiments, the composition further comprises a dermatologically acceptable carrier. Such compositions are useful for reducing body odor.

Abstract: This disclosure relates to topical personal care compositions comprising one or more of a yeast component; a Bacillaceae extract; and 13-methyltetradecanoate; and B) one or more of: a phytochemical; an organic acid; and an antimicrobial peptide. In some embodiments, a composition as described herein can include a yeast component present in an amount of at least about 0.5% w/w of the composition; caffeine present in an amount of about 0.05% to about 5% w/w of the composition; a lemon grass extract present in an amount of at least about 0.01% to about 5% w/w of the composition; and an citrus fruit extract present in an amount of at least about 0.01% to about 5% w/w of the composition. In some embodiments, the composition further comprises a dermatologically acceptable carrier. Such compositions are useful for reducing body odor.

Abstract: The present disclosure relates to compositions comprising dietary fibers. For example, in some embodiments, the composition comprises two or more fibers (e.g., fibers such as wheat dextrin, inulin, pectin, or potato starch) each present in amount of about 2% to about 6% w/w of the composition. The present disclosure also relates to partially hydrolyzed dietary fibers and methods to prepare a partially hydrolyzed dietary. In some embodiments, the composition comprises further comprises an acid and/or a preservative present in an amount of about 0.01% to about 2% w/w of the composition. In some embodiments, the composition further includes a sweetener and/or a flavoring agent. Such compositions are useful in the treatment or improvement of gastrointestinal diseases.

Abstract: The present disclosure relates to topical compositions comprising one or more topical anesthetics or analgesics; a vitamin B3 compound; and a coating agent. In some embodiments, the composition comprises about 1% to about 10% w/w of the composition of the topical anesthetic, topical analgesic, or a combination thereof; about 1% to about 10% w/w of the composition of the vitamin B3 compound; and about 5% to about 50% w/w of the composition of the coating agent. In some embodiments, the composition further includes a pharmaceutically acceptable base. In some embodiments, the pharmaceutically acceptable base comprises about 35% to about 85% w/w of the composition of a pharmaceutically acceptable oil; about 1% to about 20% w/w of the composition of a pharmaceutically acceptable wax; or a combination thereof. Such compositions are useful for treating anal itch or pruritus ani.

Abstract: The present disclosure relates to compositions comprising dietary fibers. For example, in some embodiments, the composition comprises two or more fibers (e.g., fibers such as wheat dextrin, inulin, pectin, or potato starch) each present in amount of about 2% to about 6% w/w of the composition. The present disclosure also relates to partially hydrolyzed dietary fibers and methods to prepare a partially hydrolyzed dietary. In some embodiments, the composition comprises further comprises an acid and/or a preservative present in an amount of about 0.01% to about 2% w/w of the composition. In some embodiments, the composition further includes a sweetener and/or a flavoring agent. Such compositions are useful in the treatment or improvement of gastrointestinal diseases.

Abstract: The present disclosure relates to topical compositions comprising a dermo-muscle relaxant, and optionally, one or more topical anesthetics or analgesics; a vitamin B3 compound; and/or a pharmaceutically acceptable plant extract. In some embodiments, the composition includes about 10% to about 20% w/w of the composition of the dermo-muscle relaxant. In some embodiments, the composition further includes about 1% to about 10% w/w of the composition of the topical anesthetic, topical analgesic, or a combination thereof. In some embodiments, the composition further includes a pharmaceutically acceptable base. In some embodiments, the pharmaceutically acceptable base comprises about 35% to about 95% w/w of the composition of a pharmaceutically acceptable oil, about 5% to about 25% w/w of the composition of a pharmaceutically acceptable wax, or a combination thereof. Such compositions are useful for treating anal fissure and cuts, abrasions, injuries, burns, and/or breakages on the skin.

Abstract: The present disclosure relates to topical compositions comprising one or more topical anesthetics or analgesics; a vitamin B3 compound; and a coating agent. In some embodiments, the composition comprises about 1% to about 10% w/w of the composition of the topical anesthetic, topical analgesic, or a combination thereof; about 1% to about 10% w/w of the composition of the vitamin B3 compound; and about 5% to about 50% w/w of the composition of the coating agent. In some embodiments, the composition further includes a pharmaceutically acceptable base. In some embodiments, the pharmaceutically acceptable base comprises about 35% to about 85% w/w of the composition of a pharmaceutically acceptable oil; about 1% to about 20% w/w of the composition of a pharmaceutically acceptable wax; or a combination thereof. Such compositions are useful for treating anal itch or pruritus ani.