Patents by Inventor Mohamad GARA

Mohamad GARA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of 14-methyl-16-oxabicyclo[10.3.1]hexadec-12-ene
    Patent number: 11753417
    Abstract: Disclosed is a scalable process for preparation of 14-methyl-16-oxabicyclo[10.3.1]hexadec-12-ene (BCE), a key intermediate for manufacture of fragrance ingredient 3-methylcyclopentadecenone (MUSCENONE®) and analogs through reaction of 3-Methyl-1,5-cyclopentadecanedione (MCPD) and analogs with a metal or metalloid alkoxide in high yield and purity.
    Type: Grant
    Filed: January 16, 2020
    Date of Patent: September 12, 2023
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Mohamad Gara, Yigal Becker
  • DIHYDROXYLATION OF OLEFINS USING OSMATE (VI) SALTS
    Publication number: 20220388931
    Abstract: A highly efficient synthesis of cis-diol compounds through cis-dihydroxylation of olefins using osmate (VI) salt as catalysts is disclosed, which has found important application in efficient large-scale preparation of, among others, ?,?-cedranediol from ?-cedrene.
    Type: Application
    Filed: November 4, 2020
    Publication date: December 8, 2022
    Inventors: YIGAL BECKER, MOHAMAD GARA
  • SYNTHESIS OF 14-METHYL-16-OXABICYCLO[10.3.1]HEXADEC-12-ENE
    Publication number: 20220127278
    Abstract: Disclosed is a scalable process for preparation of 14-methyl-16-oxabicyclo[10.3.1]hexadec-12-ene (BCE), a key intermediate for manufacture of fragrance ingredient 3-methylcyclopentadecenone (MUSCENONE®) and analogs through reaction of 3-Methyl-1,5-cyclopentadecanedione (MCPD) and analogs with a metal or metalloid alkoxide in high yield and purity.
    Type: Application
    Filed: January 16, 2020
    Publication date: April 28, 2022
    Inventors: Mohamad Gara, Yigal Becker
  • Cyclopropanation of substituted alkenes
    Patent number: 10584080
    Abstract: Disclosed is a cyclopropanation process comprising the step of reacting an alkene compound having at least one carbon-carbon double bond with at least one dihaloalkane. The reaction is carried out in the presence of (i) particulate metal Zn, (ii) catalytically effective amount of particulate metal Cu or a salt thereof, (iii) at least one haloalkylsilane, and (iv) at least one solvent.
    Type: Grant
    Filed: February 1, 2019
    Date of Patent: March 10, 2020
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Mohamad Gara, Yigal Becker
  • CYCLOPROPANATION OF SUBSTITUTED ALKENES
    Publication number: 20190177247
    Abstract: Disclosed is a cyclopropanation process comprising the step of reacting an alkene compound having at least one carbon-carbon double bond with at least one dihaloalkane. The reaction is carried out in the presence of (i) particulate metal Zn, (ii) catalytically effective amount of particulate metal Cu or a salt thereof, (iii) at least one haloalkylsilane, and (iv) at least one solvent.
    Type: Application
    Filed: February 1, 2019
    Publication date: June 13, 2019
    Applicant: International Flavors & Fragrances Inc.
    Inventors: Mohamad Gara, Yigal Becker
  • Cyclopropanation of substituted alkenes
    Patent number: 10227269
    Abstract: Disclosed is a cyclopropanation process comprising the step of reacting an alkene compound having at least one carbon-carbon double bond with at least one dihaloalkane. The reaction is carried out in the presence of (i) particulate metal Zn, (ii) catalytically effective amount of particulate metal Cu or a salt thereof, (iii) at least one haloalkylsilane, and (iv) at least one solvent.
    Type: Grant
    Filed: August 4, 2016
    Date of Patent: March 12, 2019
    Assignee: International Flavors & Fragances Inc.
    Inventors: Mohamad Gara, Yigal Becker
  • CYCLOPROPANATION OF SUBSTITUTED ALKENES
    Publication number: 20180170830
    Abstract: Disclosed is a cyclopropanation process comprising the step of reacting an alkene compound having at least one carbon-carbon double bond with at least one dihaloalkane. The reaction is carried out in the presence of (i) particulate metal Zn, (ii) catalytically effective amount of particulate metal Cu or a salt thereof, (iii) at least one haloalkylsilane, and (iv) at least one solvent.
    Type: Application
    Filed: August 4, 2016
    Publication date: June 21, 2018
    Inventors: Mohamad GARA, Yigal BECKER