Patents by Inventor Mohamad Saleh Alsalhi

Mohamad Saleh Alsalhi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11952496
    Abstract: The present subject matter relates to a new liquid and solid-state laser system comprising a laser structure and novel 7H-pyrano[2,3-b:4,5-b?]diquinoline derivative compounds as the laser active media; the novel 7H-pyrano[2,3-b:4,5-b?]diquinoline derivative compounds comprising 10-chloro-7H-pyrano[2,3-b:4,5-b?]diquinoline [(Cl-PD)] and 10-methoxy-7H-pyrano[2,3-b:4,5-b?]diquinoline [(MeO-PD)]; and a method of synthesizing the organic 7H-pyrano[2,3-b:4,5-b?]diquinoline derivative compounds used in the laser system.
    Type: Grant
    Filed: May 2, 2023
    Date of Patent: April 9, 2024
    Assignee: KING SAUD UNIVERSITY
    Inventors: Abdulrahman I Almansour, Saradh Prasad Rajendra, Mohamad Saleh Alsalhi, Natarajan Arumugam, Raju Suresh Kumar
  • Patent number: 11696925
    Abstract: Calcium hydroxide nanoparticles (Ca(OH)2NPs) synthesized using carob pulp extract may be hexagonal nanoparticles with a diameter ranging from about 31.22 nm to about 81.22 nm. The Ca(OH)2NPs may be synthesized by heating ethylene glycol, adding calcium hydroxide to the ethylene glycol to provide a first mixture, heating the first mixture, adding a carob pulp aqueous extract to the first mixture to form a second mixture, heating the second mixture, adding sodium hydroxide (NaOH) to the second mixture to form a third mixture, heating the third mixture, resting the third mixture at room temperature after heating, centrifuging the third mixture, collecting a colloid sediment, extracting any unwanted contaminants from the colloid sediment, and drying the colloid sediment to obtain Ca(OH)2NPs.
    Type: Grant
    Filed: September 14, 2020
    Date of Patent: July 11, 2023
    Assignee: KING SAUD UNIVERSITY
    Inventors: Mohamad Saleh Alsalhi, Sandhanasamy Devanesan, Rawan Ibrahim Salem Alkhalaf, Hajer Saad Abdullah Allayed, Nasser Raqe Rashed Alqhtani, Mohammed Ghazi Alkindi, Osama Ghurmullah Mohammed Alghamdi
  • Publication number: 20210000865
    Abstract: Calcium hydroxide nanoparticles (Ca(OH)2NPs) synthesized using carob pulp extract may be hexagonal nanoparticles with a diameter ranging from about 31.22 nm to about 81.22 nm. The Ca(OH)2NPs may be synthesized by heating ethylene glycol, adding calcium hydroxide to the ethylene glycol to provide a first mixture, heating the first mixture, adding a carob pulp aqueous extract to the first mixture to form a second mixture, heating the second mixture, adding sodium hydroxide (NaOH) to the second mixture to form a third mixture, heating the third mixture, resting the third mixture at room temperature after heating, centrifuging the third mixture, collecting a colloid sediment, extracting any unwanted contaminants from the colloid sediment, and drying the colloid sediment to obtain Ca(OH)2NPs.
    Type: Application
    Filed: September 14, 2020
    Publication date: January 7, 2021
    Inventors: MOHAMAD SALEH ALSALHI, SANDHANSAMY DEVANESAN, RAWAN IBRAHIM SALEM ALKHALAF, HAJER SAAD ABDULLAH ALLAYED, NASSER RAQE RASHED ALQHTANI, MOHAMMED GHAZI ALKINDI, OSAMA GHURMULLAH MOHAMMED ALGHAMDI
  • Publication number: 20200405749
    Abstract: Calcium hydroxide nanoparticles (Ca(OH)2NPs) synthesized using carob pulp extract may be hexagonal nanoparticles with a diameter ranging from about 31.22 nm to about 81.22 nm. The Ca(OH)2NPs may be synthesized by heating ethylene glycol, adding calcium hydroxide to the ethylene glycol to provide a first mixture, heating the first mixture, adding a carob pulp aqueous extract to the first mixture to form a second mixture, heating the second mixture, adding sodium hydroxide (NaOH) to the second mixture to form a third mixture, heating the third mixture, resting the third mixture at room temperature after heating, centrifuging the third mixture, collecting a colloid sediment, extracting any unwanted contaminants from the colloid sediment, and drying the colloid sediment to obtain Ca(OH)2NPs.
    Type: Application
    Filed: September 14, 2020
    Publication date: December 31, 2020
    Inventors: MOHAMAD SALEH ALSALHI, SANDHANSAMY DEVANESAN, RAWAN IBRAHIM SALEM ALKHALAF, HAJERSAAD ABDULLAH ALLAYED, NASSER RAQE RASHED ALQHTANI, MOHAMMED GHAZI ALKINDI, OSAMA GHURMULLAH M. ALGHAMDI
  • Patent number: 10879668
    Abstract: The solid state laser with conjugated oligomer active material uses a lasing medium including a conjugated oligomer embedded in a transparent crystal matrix. The lasing medium preferably also includes a thermally conductive material. A pump laser generates a pump laser beam to impinge on the lasing medium, causing the lasing medium to generate at least one amplified spontaneous emission laser beam. The transparent crystal matrix may be formed from an epoxy thermosetting plastic, such as that formed from a hardener and an epoxy, such as isobornyl acrylate, ethyl 2-cyanoacrylate, ethyl 2-cyano-3,3-bis(methylthio)acrylate, ethyl cyanoacrylate, ethyl cis-(?-cyano)acrylate, poly(bisphenol A-co-epichlorohydrin) or bisphenol A. The conjugated oligomer may be 1,4-bis(9-ethyl-3-carbazo-vinylene)-9,9-dihexyl-fluorene (BECVH-DHF). The thermally conductive material may be molybdenum disulfide (MoS2) or [6,6]-phenyl-C61-butyric acid methyl ester (PCBM 60).
    Type: Grant
    Filed: March 9, 2020
    Date of Patent: December 29, 2020
    Assignee: KING SAUD UNIVERSITY
    Inventors: Mohamad Saleh Alsalhi, Mamduh Jamil Aljaafreh, Saradh Prasad Rajendra
  • Patent number: 10780111
    Abstract: Calcium hydroxide nanoparticles (Ca(OH)2NPs) synthesized using carob pulp extract may be hexagonal nanoparticles with a diameter ranging from about 31.22 nm to about 81.22 nm. The Ca(OH)2NPs may be synthesized by heating ethylene glycol, adding calcium hydroxide to the ethylene glycol to provide a first mixture, heating the first mixture, adding a carob pulp aqueous extract to the first mixture to form a second mixture, heating the second mixture, adding sodium hydroxide (NaOH) to the second mixture to form a third mixture, heating the third mixture, resting the third mixture at room temperature after heating, centrifuging the third mixture, collecting a colloid sediment, extracting any unwanted contaminants from the colloid sediment, and drying the colloid sediment to obtain Ca(OH)2NPs.
    Type: Grant
    Filed: April 29, 2019
    Date of Patent: September 22, 2020
    Assignee: KING SAUD UNIVERSITY
    Inventors: Mohamad Saleh Alsalhi, Sandhansamy Devanesan, Rawan Ibrahim Salem Alkhalaf, Hajer Saad Abdullah Allayed, Nasser Raqe Rashed Alqhtani, Mohammed Ghazi Alkindi, Osama Ghurmullah Mohammed Alghamdi
  • Patent number: 10541506
    Abstract: The conjugated polymer laser with temperature-controlled power output uses a triphenylamine dimer-based conjugated polymer as the laser medium to produce an output laser beam having a beam energy tunable between approximately 20 ?J and approximately 325 ?J over a temperature range of the triphenylamine dimer-based conjugated polymer between approximately 40° C. and approximately 85° C. The triphenylamine dimer-based conjugated polymer laser medium is a solution of poly[N,N?-bis(4-butylphenyl)-N,N?-bisphenylbenzidine], known as poly-TPD(4B), dissolved in toluene. Poly-TPD(4B) has a long side chain of butyl (C4H9), providing temperature-dependent dimerization, which may not be found with shorter chains of butyl, such as in poly-TPD(4E) or poly-TPD(4M). The molar concentration of the poly-TPD in the solution is between approximately 5 ?M and approximately 100 ?M.
    Type: Grant
    Filed: April 10, 2019
    Date of Patent: January 21, 2020
    Assignee: King Saud University
    Inventors: Saradh Prasad Rajendra, Mohamad Saleh Alsalhi, Mamduh Jamil Aljaafreh
  • Publication number: 20180333433
    Abstract: A method of synthesizing silver nanoparticles includes using sesame (Sesamum indicum) oil cake extract as a reducing agent. The silver nanoparticles can range in size from about 6 nm to about 15 nm. The silver nanoparticles can have an average particle size of about 10 nm.
    Type: Application
    Filed: May 18, 2017
    Publication date: November 22, 2018
    Inventors: MOHAMAD SALEH ALSALHI, SANDHANASAMY DEVANESAN, AKRAM AHMED ALFURAYDI, MYSOON M.F. AL-ANSARI
  • Patent number: 10111918
    Abstract: A method of preparing biologically active derivatives from Calotropis gigantea flowers includes obtaining fresh Calotropis gigantea flowers, drying the flesh flowers, soaking the dried flowers in a natural oil, e.g., almond oil, and burning the oil-soaked flowers to provide flower ash, the flower ash including the biologically active derivatives. The flower ash can be toxin free.
    Type: Grant
    Filed: March 2, 2018
    Date of Patent: October 30, 2018
    Assignee: KING SAUD UNIVERSITY
    Inventors: Devanesan Sandhanasamy, Mohamad Saleh Alsalhi, Periyasami Govindasami, Ali Kanakhir Aldalbahi
  • Patent number: 10059601
    Abstract: The synthesis of silver nanoparticles from plant extract includes providing a solution including silver nitrate; providing an aqueous extract of the Abelmoschus esculentus (Okra) plant or plant part; mixing the silver nitrate solution and the extract solution to form an aqueous mixture; and resting the aqueous mixture for a period of time to form silver nanoparticles (AgNPs). The resulting silver nanoparticles demonstrate antimicrobial activity against both gram-positive and gram-negative pathogens.
    Type: Grant
    Filed: October 11, 2017
    Date of Patent: August 28, 2018
    Assignee: KING SAUD UNIVERSITY
    Inventors: Mohamad Saleh Alsalhi, Sandhanasamy Devanesan
  • Patent number: 9733187
    Abstract: The method of detecting bladder cancer by optical analysis of bodily fluids utilizes optical techniques to determine a concentration of porphyrin in a patient's bodily fluid sample. The patient is administered 5-aminolevulinic acid and, approximately eight hours later, a bodily fluid sample is collected from the patient, and this bodily fluid sample is optically analyzed to measure a concentration of porphyrin therein. Optical analysis is preferably performed by laser-induced fluorescence spectroscopy. If the measured concentration of porphyrin is approximately three times a pre-determined porphyrin concentration for a healthy person of the same age as the patient, then the patient is diagnosed with bladder cancer.
    Type: Grant
    Filed: March 6, 2015
    Date of Patent: August 15, 2017
    Assignee: King Saud University
    Inventors: Vadivel Masilamani, Mohamad Saleh Alsalhi, Karim Hamda Farhat, Danny Monther Rabah, Saradh Prasad, Sandhanasamy Devanesan
  • Patent number: 9726679
    Abstract: The spectral method for quantifying hemoglobin fragility caused by smoking is based on decreased concentration of tryptophan and elevated concentrations of the biomolecules nicotinamide adenine dinucleotide (NADH), flavin adenine dinucleotide (FAD), and porphyrin in the presence of hemoglobin fragility. The method involves the steps of obtaining a blood sample from a patient who is a smoker; separating blood plasma from the samples; obtaining synchronous excitation spectra (SXS) of the blood plasma with a spectrofluorometer at a scan offset of 70 nm and at a scan offset of 10 nm; comparing the patient's SXS with the SXS of normal control samples; and diagnosing hemoglobin fragility when the excitation maxima of NADH, FAD, and porphyrin are between 30% and 70% higher than the maxima for these metabolites in the normal control samples, or when the excitation maximum for tryptophan is 60% of the control sample.
    Type: Grant
    Filed: July 28, 2015
    Date of Patent: August 8, 2017
    Assignee: King Saud University
    Inventors: Vadivel Masilamani, Mohamad Saleh Alsalhi, Sandhanasamy Devanesan
  • Patent number: 9698561
    Abstract: The temperature tuned conjugated polymer laser uses a thiophene-based conjugated polymer as the laser medium to produce an output laser beam having a wavelength tunable between approximately 552 nm and approximately 612 nm over a temperature range of the thiophene-based conjugated polymer between approximately 60° C. and approximately 10° C., with an overall tunability of about 1.2 nm/° C. The thiophene-based conjugated polymer laser medium is a solution of poly[3-(2-ethyl-isocyanato-octadecanyl)-thiophene] dissolved in tetrahydrofuran (THF). A temperature controller selectively and controllably adjusts the temperature of the thiophene-based conjugated polymer to selectively and controllably tune the wavelength of the output laser beam.
    Type: Grant
    Filed: January 3, 2017
    Date of Patent: July 4, 2017
    Assignee: KING SAUD UNIVERSITY
    Inventors: Saradh Prasad Rajendra, Mohamad Saleh Alsalhi, Vadivel Masilamani
  • Publication number: 20170030931
    Abstract: The spectral method for quantifying hemoglobin fragility caused by smoking is based on decreased concentration of tryptophan and elevated concentrations of the biomolecules nicotinamide adenine dinucleotide (NADH), flavin adenine dinucleotide (FAD), and porphyrin in the presence of hemoglobin fragility. The method involves the steps of obtaining a blood sample from a patient who is a smoker; separating blood plasma from the samples; obtaining synchronous excitation spectra (SXS) of the blood plasma with a spectrofluorometer at a scan offset of 70 nm and at a scan offset of 10 nm; comparing the patient's SXS with the SXS of normal control samples; and diagnosing hemoglobin fragility when the excitation maxima of NADH, FAD, and porphyrin are between 30% and 70% higher than the maxima for these metabolites in the normal control samples, or when the excitation maximum for tryptophan is 60% of the control sample.
    Type: Application
    Filed: July 28, 2015
    Publication date: February 2, 2017
    Inventors: VADIVEL MASILAMANI, MOHAMAD SALEH ALSALHI, SANDHANASAMY DEVANESAN
  • Publication number: 20160258871
    Abstract: The method of detecting bladder cancer by optical analysis of bodily fluids utilizes optical techniques to determine a concentration of porphyrin in a patient's bodily fluid sample. The patient is administered 5-aminolevulinic acid and, approximately eight hours later, a bodily fluid sample is collected from the patient, and this bodily fluid sample is optically analyzed to measure a concentration of porphyrin therein. Optical analysis is preferably performed by laser-induced fluorescence spectroscopy. If the measured concentration of porphyrin is approximately three times a pre-determined porphyrin concentration for a healthy person of the same age as the patient, then the patient is diagnosed with bladder cancer.
    Type: Application
    Filed: March 6, 2015
    Publication date: September 8, 2016
    Inventors: VADIVEL MASILAMANI, MOHAMAD SALEH ALSALHI, KARIM HAMDA FARHAT, DANNY MONTHER RABAH, SARADH PRASAD, SANDHANASAMY DEVANESAN
  • Patent number: 9144544
    Abstract: The synthesis of silver nanoparticles from Pimpinella anisum L seeds includes providing a silver nitrate (AgNO3) solution, providing an extract of Pimpinella anisum L. plant seeds, and combining the silver nitrate solution with the extract of the Pimpinella anisum L. plant seeds to produce silver nanoparticles. The synthesis of silver nanoparticles from Pimpinella anisum L. seeds does not require toxic chemical solvents.
    Type: Grant
    Filed: February 10, 2015
    Date of Patent: September 29, 2015
    Assignee: KING SAUD UNIVERSITY
    Inventors: Mohamad Saleh Alsalhi, Akram Ahmed Alfuraydi, Sandhanasamy Devanesan
  • Patent number: 9011766
    Abstract: A method for increasing the shelf life of donor blood contemplates the following steps. In the first step blood is transferred to a sterile container and mixed with an anticoagulant as indicated in step 20. The anticoagulant and donor blood are centrifuged in step 22 at about 4,000 rpm for about 15 minutes. After centrifuging the red blood cells are separated and placed in a sterile tube. In the next step the red blood cells are irradiated by a laser that emanates a wavelength of about 633 nm for a time period of about 24 hours. During rotation the RBCs are rotated to provide uniform exposure. Such laser biostimulation produces an enhancement of shelf life of donor blood by 66%.
    Type: Grant
    Filed: November 19, 2012
    Date of Patent: April 21, 2015
    Assignee: King Saud University
    Inventors: Al-Khalid Isam Zuhaier, Mohamad Saleh AlSalhi, Vadivel Masilamani
  • Publication number: 20140140889
    Abstract: A method for increasing the shelf life of donor blood contemplates the following steps. In the first step blood is transferred to a sterile container and mixed with an anticoagulant as indicated in step 20. The anticoagulant and donor blood are centrifuged in step 22 at about 4,000 rpm for about 15 minutes. After centrifuging the red blood cells are separated and placed in a sterile tube. In the next step the red blood cells are irradiated by a laser that emanates a wavelength of about 633 nm for a time period of about 24 hours. During rotation the RBCs are rotated to provide uniform exposure. Such laser biostimulation produces an enhancement of shelf life of donor blood by 66%.
    Type: Application
    Filed: November 19, 2012
    Publication date: May 22, 2014
    Applicant: King Saud University
    Inventors: Al-Khalid Isam Zuhaier, Mohamad Saleh AlSalhi, Vadivel Masilamani
  • Patent number: 8367769
    Abstract: Embodiments of the invention provide silicon-based nanoparticle composites, where the silicon nanoparticles are highly luminescent. Preferred embodiments of the invention are Si—O solid composite networks, e.g., glass, having a homogenous distribution of luminescent hydrogen terminated silicon nanoparticles in a homogenous distribution throughout the solid. Embodiments of the invention also provide fabrication processes for silicon-based silicon nanoparticle composites. A preferred method for forming a silicon-based nanoparticle composite disperses hydrogen terminated silicon nanoparticles and an inorganic precursor of an organosilicon gel in an aprotic solvent to form a sol. A catalyst is mixed into the sol. The sol is then permitted to dry into a gel of the silicon-based nanoparticle composite.
    Type: Grant
    Filed: February 17, 2010
    Date of Patent: February 5, 2013
    Assignee: NanoSi Advanced Technologies, Inc.
    Inventors: Abdullah Saleh Aldwayyan, Mohamad Saleh AlSalhi, Abdurahman Mohammed Aldukhail, Mansour S. Alhoshan, Muhammad Naziruddin Khan, Ghassan K. Al-Chaar, Munir Nayfeh
  • Patent number: 8213005
    Abstract: The method for discriminating between benign and malignant prostate tumors relates to analyzing samples of blood, urine and tissue by fluorescence spectroscopy in order to detect the presence of naturally occurring molecules in the fluids and tissue that serve as biomarkers indicative of cancer in the human body. The analysis can be carried out based on fluorescence emission spectra, fluorescence excitation spectra and synchronous (emission and excitation) spectra of bio-samples. The detection, diagnosis, and follow-up and also discrimination between malignant and benign prostate tumors may be made by comparison of ratios of fluorescence emissions and/or excitation intensities of tryptophan, tyrosine, elastin, collagen, bile pigments, NADH, flavins and various species of porphyrins.
    Type: Grant
    Filed: December 31, 2009
    Date of Patent: July 3, 2012
    Assignee: King Saud University
    Inventors: Vadivel Masilamani, Danny M. Rabah, Mohamad Saleh Alsalhi