Patents by Inventor Mohamed A. Iqbal

Mohamed A. Iqbal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thio-substituted biaryl-methanesulfinyl derivatives
    Patent number: 7449481
    Abstract: The present invention is related to chemical compositions, processes for the preparation thereof and uses of the composition. Particularly, the present invention relates to compositions that include substituted biaryl-methanesulfinyl acetamides of Formula (I): wherein Ar, Y, R1, R2, R4, R5, q and x are as defined herein; and their use in the treatment of diseases, including treatment of sleepiness associated with narcolepsy, obstructive sleep apnea, or shift work disorder; Parkinson's disease; Alzheimer's disease; attention deficit disorder; attention deficit hyperactivity disorder; depression; or fatigue associated with a neurological disease; as well as the promotion of wakefulness.
    Type: Grant
    Filed: April 12, 2005
    Date of Patent: November 11, 2008
    Assignee: Cephalon, Inc.
    Inventors: Edward R. Bacon, Sankar Chatterjee, Derek Dunn, Marie-Edith Gourdel, Greg Hostetler, Mohamed Iqbal, Brigitte Lesur, Philippe Louvet, Eric Riguet, Dominique Schweizer, Christophe Yue
  • Bicyclic aromatic sulfinyl derivatives
    Patent number: 7423176
    Abstract: The present invention provides compounds of the structure: wherein the constituent members are defined herein, including pharmaceutical compositions thereof and methods of treating diseases therewith.
    Type: Grant
    Filed: April 12, 2005
    Date of Patent: September 9, 2008
    Assignees: Cephalon, Inc., Cephalon France
    Inventors: Edward R. Bacon, Sankar Chatterjee, Mohamed Iqbal, Brigitte Lesur, Philippe Louvet
  • Proteasome inhibitors and methods of using the same
    Patent number: 7223745
    Abstract: The present invention provides boronic acid compounds, boronic esters, and compositions thereof that can modulate apoptosis such as by inhibition of proteasome activity. The compounds and compositions can be used in methods of inducing apoptosis and treating diseases such as cancer and other disorders associated directly of indirectly with proteasome activity.
    Type: Grant
    Filed: August 12, 2004
    Date of Patent: May 29, 2007
    Assignee: Cephalon, Inc.
    Inventors: Sankar Chatterjee, Mohamed Iqbal, Ernesto Menta, Ambrogio Oliva
  • Power estimation of a transmission
    Publication number: 20070004349
    Abstract: Embodiments of power estimation of a transmission are presented herein.
    Type: Application
    Filed: June 29, 2005
    Publication date: January 4, 2007
    Inventors: Thirunavukkarasu Ranganathan, Mohamed Iqbal, Vijayakumaran Nair
  • Thio-substituted biaryl-methanesulfinyl derivatives
    Publication number: 20050245747
    Abstract: The present invention is related to chemical compositions, processes for the preparation thereof and uses of the composition. Particularly, the present invention relates to compositions that include substituted biaryl-methanesulfinyl acetamides of Formula (I): wherein Ar, Y, R1, R2, R4, R5, q and x are as defined herein; and their use in the treatment of diseases, including treatment of sleepiness associated with narcolepsy, obstructive sleep apnea, or shift work disorder; Parkinson's disease; Alzheimer's disease; attention deficit disorder; attention deficit hyperactivity disorder; depression; or fatigue associated with a neurological disease; as well as the promotion of wakefulness.
    Type: Application
    Filed: April 12, 2005
    Publication date: November 3, 2005
    Applicants: Cephalon, Inc., Cephalon France
    Inventors: Edward Bacon, Sankar Chatterjee, Derek Dunn, Marie-Edith Gourdel, Greg Hostetler, Mohamed Iqbal, Brigitte Lesur, Philippe Louvet, Eric Riguet, Dominique Schweizer, Christophe Yue
  • Bicyclic aromatic sulfinyl derivatives
    Publication number: 20050228040
    Abstract: The present invention provides compounds of the structure: wherein the constituent members are defined herein, including pharmaceutical compositions thereof and methods of treating diseases therewith.
    Type: Application
    Filed: April 12, 2005
    Publication date: October 13, 2005
    Applicants: Cephalon, Inc., Cephalon France
    Inventors: Edward Bacon, Sankar Chatterjee, Mohamed Iqbal, Brigitte Lesur, Philippe Louvet
  • Proteasome inhibitors and methods of using the same
    Publication number: 20050107307
    Abstract: The present invention provides boronic acid compounds, boronic esters, and compositions thereof that can modulate apoptosis such as by inhibition of proteasome activity. The compounds and compositions can be used in methods of inducing apoptosis and treating diseases such as cancer and other disorders associated directly of indirectly with proteasome activity.
    Type: Application
    Filed: August 12, 2004
    Publication date: May 19, 2005
    Inventors: Raffaella Bernadini, Alberto Bernareggi, Paolo Cassara, Sankar Chatterjee, Germano D'Arasmo, Sergio De Munari, Edmondo Ferretti, Mohamed Iqbal, Ernesto Menta, Patricia Messina McLaughlin, Ambrogio Oliva
  • Proteasome inhibitors and methods of using the same
    Publication number: 20050059636
    Abstract: The present invention provides boronic acid compounds, boronic esters, and compositions thereof that can modulate apoptosis such as by inhibition of proteasome activity. The compounds and compositions can be used in methods of inducing apoptosis and treating diseases such as cancer and other disorders associated directly of indirectly with proteasome activity.
    Type: Application
    Filed: August 12, 2004
    Publication date: March 17, 2005
    Inventors: Sankar Chatteriee, Mohamed Iqbal, Ernesto Menta, Ambrogio Oliva
  • Treating retinal neuronal disorders by the application of insulin-like growth factors and analogs
    Patent number: 6310040
    Abstract: Disclosed is a method for promoting retinal neuronal survival in a mammal, wherein the neuronal cells are at risk of dying. The method comprises administering to the mammal an effective dose of at least one of the following substances: IGF-I; a functional derivative of IGF-I; IGF-II; or a functional derivative of IGF-II.
    Type: Grant
    Filed: October 15, 1992
    Date of Patent: October 30, 2001
    Assignee: Cephalon, Inc.
    Inventors: Donna Bozyczko-Coyne, Nicola Neff, Michael E. Lewis, Mohamed A. Iqbal
  • Multicatalytic protease inhibitors
    Patent number: 5990083
    Abstract: Disclosed herein are inhibitors of the multicatalytic protease enzyme which are represented by the general formula: ##STR1## Constituent members and preferred constituent members are disclosed herein. Methodologies for making and using the disclosed compounds are also set forth herein.
    Type: Grant
    Filed: March 13, 1997
    Date of Patent: November 23, 1999
    Assignee: Cephalon, Inc.
    Inventors: Mohamed Iqbal, James L. Diebold, Robert Siman, Sankar Chatterjee, James C. Kauer
  • Multicatalytic protease inhibitors
    Patent number: 5830870
    Abstract: Disclosed herein are inhibitors of the multicatalytic protease enzyme which are represented by the general formula: ##STR1## Constituent members and preferred constituent members are disclosed herein. Methodologies for making and using the disclosed compounds are also set forth herein.
    Type: Grant
    Filed: December 4, 1996
    Date of Patent: November 3, 1998
    Assignee: Cephalon, Inc.
    Inventors: Mohamed Iqbal, James L. Diebold, Robert Siman, Sankar Chatterjee, James C. Kauer
  • Treating disorders by application of insulin-like growth factors and analogs
    Patent number: 5776897
    Abstract: A method of enhancing the survival of neuronal cells in a mammal, the cells being at risk of dying, the method comprising administering to the mammal an effective amount of one of the following substances: IGF-I; a functional derivative of IGF-I; IGF-II; a functional derivative of IGF-II; IGF-III; or a functional derivative of IGF-III.
    Type: Grant
    Filed: March 24, 1997
    Date of Patent: July 7, 1998
    Assignee: Cephalon, Inc.
    Inventors: Michael E. Lewis, James C. Kauer, Kevin R. Smith, Kathleen V. Callison, Frank Baldino, Nicola Neff, Mohamed Iqbal
  • Treating disorders by application of insulin-like growth factors and analogs
    Patent number: 5703045
    Abstract: A method of enhancing the survival of neuronal cells in a mammal, the cells being at risk of dying, the method comprising administering to the mammal an effective amount of at least one of the following substances: IGF-I; a functional derivative of IGF-I; IGF-II; a functional derivative of IGF-II; IGF-III; or a functional derivative of IGF-III.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: December 30, 1997
    Assignee: Cephalon, Inc.
    Inventors: Michael E. Lewis, James C. Kauer, Kevin R. Smith, Kathleen V. Callison, Frank Baldino, Nicola Neff, Mohamed Iqbal
  • Treating disorders by application of insulin-like growth factors and analogs
    Patent number: 5652214
    Abstract: A method of enhancing the survival of neuronal cells in a mammal, the cells being at risk of dying, the method including the step of administering to the mammal one of the following substances: IGF-I; a functional derivative of IGF-I; IGF-II; a functional derivative of IGF-II; IGF-III; or a functional derivative of IGF-III.
    Type: Grant
    Filed: October 7, 1992
    Date of Patent: July 29, 1997
    Assignee: Cephalon, Inc.
    Inventors: Michael E. Lewis, James C. Kauer, Kevin R. Smith, Kathleen V. Callison, Frank Baldino, Nicola Neff, Mohamed Iqbal
  • Multicatalytic protease inhibitors
    Patent number: 5614649
    Abstract: Disclosed herein are inhibitors of the multicatalytic protease enzyme which are represented by the general formula: ##STR1## Constituent members and preferred constituent members are disclosed herein. Methodologies for making and using the disclosed compounds are also set forth herein.
    Type: Grant
    Filed: November 3, 1995
    Date of Patent: March 25, 1997
    Assignee: Cephalon, Inc.
    Inventors: Mohamed Iqbal, James L. Diebold, Robert Siman, Sankar Chatterjee, James C. Kauer
  • Multicatalytic protease inhibitors
    Patent number: 5550262
    Abstract: Disclosed herein are inbibitors of the multicatalytic protease enzyme which are represented by the general formula: ##STR1## Constituent members and preferred constituent members are disclosed herein. Methodologies for making and using the disclosed compounds are also set forth herein.
    Type: Grant
    Filed: November 14, 1994
    Date of Patent: August 27, 1996
    Assignee: Cephalon, Inc.
    Inventors: Mohamed Iqbal, James L. Diebold, Robert Siman, Sankar Chatterjee, James C. Kauer