Patents by Inventor Mohamed A. Zayed
Mohamed A. Zayed has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240138838Abstract: An anastomosis device for joining a first and second end of a vascular vessel is disclosed that includes a polymer cylinder ending in opposed first and second vascular-retaining ends configured for insertion into the first and second ends of the vascular vessel respectively. Each vascular-retaining end includes a plurality of bristles protruding outward. The device also includes at least one moiety covalently coupled to the surface of the device. The at least one moiety is selected from at least one anti-coagulant, at least one cell-specific binding peptide, and any combination thereof.Type: ApplicationFiled: May 15, 2023Publication date: May 2, 2024Applicant: Washington UniversityInventors: Xiaowei Li, Justin Sacks, William Moritz, Emran Madatov, Mohamed Zayed
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Publication number: 20240081937Abstract: An adjustable seal includes a first ring extending about an axis and including a plurality of first teeth. The adjustable seal also includes a second ring extending about the axis and including a plurality of second teeth. The first ring and the second ring cooperatively defining a passage extending along the axis. The adjustable seal has a locked configuration in which the second teeth engage the first teeth and prevent movement of the first ring relative to the second ring, and an unlocked configuration in which the first ring is able to rotate relative to the second ring. The adjustable seal also includes a flexible member attached to the first ring and the second ring. Rotation of the first ring relative to the second ring in the unlocked configuration of the adjustable seal causes the flexible member to extend across at least a portion of the passage defined by the first ring and the second ring.Type: ApplicationFiled: January 10, 2022Publication date: March 14, 2024Inventors: Mohamed ZAYED, Chase HARTQUIST, Halle LOWE, John CASHIN
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Publication number: 20230070264Abstract: The disclosure provides for a variable stiffness catheter. The catheter may include an inner layer forming an inner lumen, a middle layer surrounding the inner layer, and an outer layer surrounding the middle layer. The middle layer may include an annular lumen and a plurality of strings within the annular lumen, and the plurality of strings may be connected to the inner layer. Applying a vacuum and evacuating the annular lumen of the middle layer alters a frictional force between the inner layer and the outer layer and thereby changes the catheter's flexural rigidity.Type: ApplicationFiled: January 25, 2021Publication date: March 9, 2023Inventors: ERIC LEUTHARDT, GUY GENIN, MOHAMED ZAYED, DANIEL HAFEZ, CHASE HARTQUIST, HALLE LOWE, VINAY CHANDRASEKARAN, JOSHUA OSBUN
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Publication number: 20230065706Abstract: A cohesive and independent hydroponic system is provided having a water tank base supporting a hollow tower for housing plants for vertical farming. The hydroponic system has a central water control system position inside the water tank base and/or the hollow of the hollow tower for centralized control and easy of scalability.Type: ApplicationFiled: August 22, 2022Publication date: March 2, 2023Inventors: Riam SHAMMAA, Mohamed ZAYED
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Publication number: 20230047991Abstract: The disclosure provides for an isovolumetric pump system for the removal of a thrombus and a method of use thereof. The isovolumetric pump system includes at least one inflow container connected to an output of the treatment region, at least one outflow container connected to an input of the treatment region, and a drawbar connecting the inflow container and the outflow container. As the drawbar is drawn back, the same quantity of fluid is drawn from the treatment region into the inflow container and injected into the treatment region from the outflow container.Type: ApplicationFiled: January 29, 2021Publication date: February 16, 2023Inventors: GUY GENIN, JOHN CASHIN, MOHAMED ZAYED, SANGHUN LEE
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Patent number: 11490910Abstract: The disclosure provides for an adjustable catheter system with isovolumetric suction and restoration of fluid for the removal of a thrombus and a method of use thereof. The catheter system includes an inner catheter and an outer sheath surrounding at least a portion of the inner catheter. The inner catheter may include at least three lumina extending from the proximal end to the distal end of the inner catheter, at least one infusion fenestration along the infusion segment, and a distal encapsulation balloon at the distal end. The outer sheath may include at least three lumina extending from the proximal end to the distal end of the outer sheath and a proximal encapsulation balloon at the distal end. The catheter system may further include an agitator for mechanical morcellation of the thrombus.Type: GrantFiled: September 7, 2021Date of Patent: November 8, 2022Assignee: Washington UniversityInventors: Eric Leuthardt, Mohamed Zayed, Guy Genin, Joshua Osbun, Gayan De Silva, Sanghun A. Lee, Dillon Williams, Alexander Wirtz
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Patent number: 11369381Abstract: An arteriovenous graft and methods of reducing the risk of graft thrombosis and extending patency of the arteriovenous graft are provided herein. The arteriovenous graft is operable for attaching to a vein at a venous anastomosis. In some aspects, the arteriovenous graft includes a plurality of grooves at a venous anastomosis end of the arteriovenous graft and the venous anastomoses may be arranged such that the arteriovenous graft and the vein meet at an angle of 30° or less.Type: GrantFiled: July 2, 2020Date of Patent: June 28, 2022Assignee: Washington UniversityInventors: Mohamed Zayed, Dillon Williams, Guy Genin, Eric Leuthardt
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Patent number: 11304832Abstract: The disclosure provides for a device and method for treating aortoiliac occlusion disease with the placement of a fenestrated stent system at the aortic bifurcation. The fenestrated stent system includes a tapered fenestrated stent with a fenestration and a common iliac stent that is placed within the fenestration of the fenestrated stent.Type: GrantFiled: April 23, 2019Date of Patent: April 19, 2022Assignee: Washington UniversityInventors: Mohamed Zayed, Alexander J. Wirtz
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Publication number: 20220047282Abstract: The disclosure provides for an adjustable catheter system with isovolumetric suction and restoration of fluid for the removal of a thrombus and a method of use thereof. The catheter system includes an inner catheter and an outer sheath surrounding at least a portion of the inner catheter. The inner catheter may include at least three lumina extending from the proximal end to the distal end of the inner catheter, at least one infusion fenestration along the infusion segment, and a distal encapsulation balloon at the distal end. The outer sheath may include at least three lumina extending from the proximal end to the distal end of the outer sheath and a proximal encapsulation balloon at the distal end. The catheter system may further include an agitator for mechanical morcellation of the thrombus.Type: ApplicationFiled: September 26, 2019Publication date: February 17, 2022Inventors: Eric Leuthardt, Mohamed Zayed, Guy Genin, Joshua Osbun, Gayan De Silva, Sanghun A. Lee, Dillon Williams, Alexander Wirtz
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Publication number: 20220040429Abstract: Devices, systems, and methods of facilitating airway management with reduced risk of release of droplets and aerosolized pathogens from the lungs of a patient are disclosed, including a bronchoscope adapter for an endotracheal tube, an endotracheal tube with integral bronchoscope adapter, an endotracheal intubation mask system, a laryngeal mask airway-specific mask system, and a quick-seal laryngeal mask airway-specific mask system.Type: ApplicationFiled: August 9, 2021Publication date: February 10, 2022Applicant: Washington UniversityInventors: Mohamed Zayed, Zahid Iqbal, Jin Vivian Lee
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Publication number: 20220034887Abstract: Among the various aspects of the present disclosure is the provision of a method of detection, treatment, and monitoring of cardiovascular disease or a foot wound by detection of a novel biomarker, Fatty Acid Synthase (FAS). Briefly, therefore, the present disclosure is directed to methods that allow for improved, noninvasive, and reliable diagnosis of these conditions, particularly in subjects suffering from Type 2 Diabetes (T2D).Type: ApplicationFiled: October 14, 2021Publication date: February 3, 2022Applicant: Washington UniversityInventors: Mohamed Zayed, Clay Semenkovich
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Publication number: 20220000498Abstract: The disclosure provides for an adjustable catheter system with isovolumetric suction and restoration of fluid for the removal of a thrombus and a method of use thereof. The catheter system includes an inner catheter and an outer sheath surrounding at least a portion of the inner catheter. The inner catheter may include at least three lumina extending from the proximal end to the distal end of the inner catheter, at least one infusion fenestration along the infusion segment, and a distal encapsulation balloon at the distal end. The outer sheath may include at least three lumina extending from the proximal end to the distal end of the outer sheath and a proximal encapsulation balloon at the distal end. The catheter system may further include an agitator for mechanical morcellation of the thrombus.Type: ApplicationFiled: September 7, 2021Publication date: January 6, 2022Inventors: Eric Leuthardt, Mohamed Zayed, Guy Genin, Joshua Osbun, Gayan De Silva, Sanghun A. Lee, Dillon Williams, Alexander Wirtz
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Patent number: 11169145Abstract: Among the various aspects of the present disclosure is the provision of a method of detection, treatment, and monitoring of cardiovascular disease or a foot wound by detection of a novel biomarker, Fatty Acid Synthase (FAS). Briefly, therefore, the present disclosure is directed to methods that allow for improved, noninvasive, and reliable diagnosis of these conditions, particularly in subjects suffering from Type 2 Diabetes (T2D).Type: GrantFiled: May 1, 2018Date of Patent: November 9, 2021Assignee: Washington UniversityInventors: Mohamed Zayed, Clay Semenkovich
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Publication number: 20210290821Abstract: Disclosed herein is a transplantation graft for transplanting cells into a patient. In an aspect, the graft may include a first graft layer having a generally cylindrical configuration defining a lumen therethrough, a coating layer surrounding the first graft layer, and a plurality of cells or vectors implanted in either the first graft layer or the coating layer. Further disclosed herein is a method for transplanting cells into a patient and a method of treating a patient in need thereof. The transplantation graft may be implanted in the patient in an arteriovenous configuration and the coating layer protects the implanted cells from the patient's immune system. The plurality of cells in the transplantation graft may release a biologically active agent in response to a biological factor in blood flowing through the lumen of the transplantation graft.Type: ApplicationFiled: July 29, 2019Publication date: September 23, 2021Applicant: Washington UniversityInventors: Mohamed A. Zayed, Jeffrey R. Millman
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Publication number: 20210000471Abstract: An arteriovenous graft and methods of reducing the risk of graft thrombosis and extending patency of the arteriovenous graft are provided herein. The arteriovenous graft is operable for attaching to a vein at a venous anastomosis. In some aspects, the arteriovenous graft includes a plurality of grooves at a venous anastomosis end of the arteriovenous graft and the venous anastomoses may be arranged such that the arteriovenous graft and the vein meet at an angle of 30° or less.Type: ApplicationFiled: July 2, 2020Publication date: January 7, 2021Applicant: Washington University, St. Louis, MOInventors: Mohamed Zayed, Dillon Williams, Guy Genin, Eric Leuthardt
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Publication number: 20190321203Abstract: The disclosure provides for a device and method for treating aortoiliac occlusion disease with the placement of a fenestrated stent system at the aortic bifurcation. The fenestrated stent system includes a tapered fenestrated stent with a fenestration and a common iliac stent that is placed within the fenestration of the fenestrated stent.Type: ApplicationFiled: April 23, 2019Publication date: October 24, 2019Applicant: Washington UniversityInventors: Mohamed Zayed, Alexander J. Wirtz
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Publication number: 20180321225Abstract: Among the various aspects of the present disclosure is the provision of a method of detection, treatment, and monitoring of cardiovascular disease or a foot wound by detection of a novel biomarker, Fatty Acid Synthase (FAS).Type: ApplicationFiled: May 1, 2018Publication date: November 8, 2018Applicant: Washington UniversityInventors: Mohamed Zayed, Clay Semenkovich