Patents by Inventor Mohamed Abdelnasser

Mohamed Abdelnasser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of making bempedoic acid and compositions of the same
    Patent number: 11926584
    Abstract: The invention provides methods of preparing 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid and methods of making a pharmaceutical material comprising a purified amount of 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid. Also provided are compositions and pharmaceutical materials including a purified amount of 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid as well as methods of treating various diseases and conditions using the compositions and pharmaceutical materials.
    Type: Grant
    Filed: April 10, 2023
    Date of Patent: March 12, 2024
    Assignee: Esperion Therapeutics, Inc.
    Inventors: Richard Copp, Mohamed Abdelnasser, Christopher M. Cimarusti, Jonathan Lane, Michael Barkman, Rasidul Amin, Arthur John Cooper, Damodaragounder Gopal, Philipp Selig
  • Methods of making bempedoic acid and compositions of the same
    Patent number: 11760714
    Abstract: The invention provides methods of preparing 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid and methods of making a pharmaceutical material comprising a purified amount of 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid. Also provided are compositions and pharmaceutical materials including a purified amount of 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid as well as methods of treating various diseases and conditions using the compositions and pharmaceutical materials.
    Type: Grant
    Filed: January 18, 2022
    Date of Patent: September 19, 2023
    Assignee: Esperion Therapeutics, Inc.
    Inventors: Richard Copp, Mohamed Abdelnasser, Christopher M. Cimarusti, Jonathan Lane, Michael Barkman, Rasidul Amin, Arthur John Cooper, Damodaragounder Gopal, Philipp Selig
  • METHODS OF MAKING BEMPEDOIC ACID AND COMPOSITIONS OF THE SAME
    Publication number: 20230250043
    Abstract: The invention provides methods of preparing 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid and methods of making a pharmaceutical material comprising a purified amount of 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid. Also provided are compositions and pharmaceutical materials including a purified amount of 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid as well as methods of treating various diseases and conditions using the compositions and pharmaceutical materials.
    Type: Application
    Filed: April 10, 2023
    Publication date: August 10, 2023
    Inventors: Richard Copp, Mohamed Abdelnasser, Christopher M. Cimarusti, Jonathan Lane, Michael Barkman, Rasidul Amin, Arthur John Cooper, Damodaragounder Gopal, Philipp Selig
  • METHODS OF MAKING BEMPEDOIC ACID AND COMPOSITIONS OF THE SAME
    Publication number: 20230183160
    Abstract: The invention provides methods of preparing 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid and methods of making a pharmaceutical material comprising a purified amount of 8-hydroxy-2,2,14, 14-tetramethylpentadecanedioic acid. Also provided are compositions and pharmaceutical materials including a purified amount of 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid as well as methods of treating various diseases and conditions using the compositions and pharmaceutical materials.
    Type: Application
    Filed: July 19, 2022
    Publication date: June 15, 2023
    Inventors: Richard Copp, Mohamed Abdelnasser, Christopher M. Cimarusti, Jonathan Lane, Michael Barkman, Rasidul Amin, Arthur John Cooper, Damodaragounder Gopal, Philipp Selig
  • SALT FORMS OF BEMPEDOIC ACID AND METHODS FOR USING THE SAME
    Publication number: 20230141635
    Abstract: The invention provides crystalline salt and cocrystal forms of bempedoic acid. Also provided are compositions and pharmaceutical materials including a crystalline salt or cocrystal form of bempedoic acid as well as methods of treating various diseases and conditions using the compositions and pharmaceutical materials.
    Type: Application
    Filed: June 19, 2020
    Publication date: May 11, 2023
    Inventors: Richard Copp, Mohamed Abdelnasser, Christopher M. Cimarusti, Chengxiang Liu
  • Methods of making bempedoic acid and compositions of the same
    Patent number: 11613511
    Abstract: The invention provides methods of preparing 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid and methods of making a pharmaceutical material comprising a purified amount of 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid. Also provided are compositions and pharmaceutical materials including a purified amount of 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid as well as methods of treating various diseases and conditions using the compositions and pharmaceutical materials.
    Type: Grant
    Filed: May 12, 2022
    Date of Patent: March 28, 2023
    Assignee: Esperion Therapeutics, Inc.
    Inventors: Richard Copp, Mohamed Abdelnasser, Christopher M. Cimarusti, Jonathan Lane, Michael Barkman, Rasidul Amin, Arthur John Cooper, Damodaragounder Gopal, Philipp Selig
  • METHODS OF MAKING BEMPEDOIC ACID AND COMPOSITIONS OF THE SAME
    Publication number: 20220388937
    Abstract: The invention provides methods of preparing 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid and methods of making a pharmaceutical material comprising a purified amount of 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid. Also provided are compositions and pharmaceutical materials including a purified amount of 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid as well as methods of treating various diseases and conditions using the compositions and pharmaceutical materials.
    Type: Application
    Filed: January 18, 2022
    Publication date: December 8, 2022
    Inventors: Richard Copp, Mohamed Abdelnasser, Christopher M. Cimarusti, Jonathan Lane, Michael Barkman, Rasidul Amin, Arthur John Cooper, Damodaragounder Gopal, Philipp Selig
  • METHODS OF MAKING BEMPEDOIC ACID AND COMPOSITIONS OF THE SAME
    Publication number: 20220281795
    Abstract: The invention provides methods of preparing 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid and methods of making a pharmaceutical material comprising a purified amount of 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid. Also provided are compositions and pharmaceutical materials including a purified amount of 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid as well as methods of treating various diseases and conditions using the compositions and pharmaceutical materials.
    Type: Application
    Filed: May 12, 2022
    Publication date: September 8, 2022
    Inventors: Richard Copp, Mohamed Abdelnasser, Christopher M. Cimarusti, Jonathan Lane, Michael Barkman, Rasidul Amin, Arthur John Cooper, Damodaragounder Gopal, Philipp Selig
  • PHARMACEUTICAL COMPOSITIONS COMPRISING GRANULATED BEMPEDOIC ACID
    Publication number: 20220249380
    Abstract: Herein disclosed are novel compositions comprising: Bempedoic acid and Bempedoic acid and Ezetimibe, kits, methods of using and processes for making said novel compositions. Notably, the formulations herein provide pharmaceutical compositions having excellent stability and release properties for both drug products. These improved formulations are useful in the treatment and prevention of cardiovascular disease.
    Type: Application
    Filed: April 14, 2022
    Publication date: August 11, 2022
    Inventors: Mohamed Abdelnasser, Pratibha S. Pilgaonkar, Anilkumar S. Gandhi
  • Methods of making bempedoic acid and compositions of the same
    Patent number: 11407705
    Abstract: The invention provides methods of preparing 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid and methods of making a pharmaceutical material comprising a purified amount of 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid. Also provided are compositions and pharmaceutical materials including a purified amount of 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid as well as methods of treating various diseases and conditions using the compositions and pharmaceutical materials.
    Type: Grant
    Filed: January 15, 2021
    Date of Patent: August 9, 2022
    Assignee: Esperion Therapeutics, Inc.
    Inventors: Richard Copp, Mohamed Abdelnasser, Christopher M. Cimarusti, Jonathan Lane, Michael Barkman, Rasidul Amin, Arthur John Cooper, Damodaragounder Gopal, Philipp Selig
  • METHODS OF MAKING BEMPEDOIC ACID AND COMPOSITIONS OF THE SAME
    Publication number: 20210139401
    Abstract: The invention provides methods of preparing 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid and methods of making a pharmaceutical material comprising a purified amount of 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid. Also provided are compositions and pharmaceutical materials including a purified amount of 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid as well as methods of treating various diseases and conditions using the compositions and pharmaceutical materials.
    Type: Application
    Filed: January 15, 2021
    Publication date: May 13, 2021
    Inventors: Richard Copp, Mohamed Abdelnasser, Christopher M. Cimarusti, Jonathan Lane, Michael Barkman, Rasidul Amin, Arthur John Cooper, Damodaragounder Gopal, Philipp Selig
  • METHODS OF MAKING BEMPEDOIC ACID AND COMPOSITIONS OF THE SAME
    Publication number: 20210139405
    Abstract: The invention provides methods of preparing 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid and methods of making a pharmaceutical material comprising a purified amount of 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid. Also provided are compositions and pharmaceutical materials including a purified amount of 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid as well as methods of treating various diseases and conditions using the compositions and pharmaceutical materials.
    Type: Application
    Filed: January 15, 2021
    Publication date: May 13, 2021
    Inventors: Richard Copp, Mohamed Abdelnasser, Christopher M. Cimarusti, Jonathan Lane, Michael Barkman, Rasidul Amin, Arthur John Cooper, Damodaragounder Gopal, Philipp Selig
  • FIXED DOSE FORMULATIONS
    Publication number: 20180338922
    Abstract: Herein disclosed are novel compositions comprising: Bempedoic acid and Bempedoic acid and Ezetimibe, kits, methods of using and processes for making said novel compositions. Notably, the formulations herein provide pharmaceutical compositions having excellent stability and release properties for both drug products. These improved formulations are useful in the treatment and prevention of cardiovascular disease.
    Type: Application
    Filed: December 29, 2017
    Publication date: November 29, 2018
    Inventors: Mohamed Abdelnasser, Pratibha S. Pilgaonkar, Anilkumar S. Gandhi