Abstract: A pre-assembled, telescoping elongate system comprising an outer elongate member surrounding a finer gauge inner elongate member which, after percutaneous penetration by the outer elongate element, extends to penetrate an intervertebral disc into which a sensing element and/or an injectable may be delivered.

Abstract: A pre-assembled, telescoping needle system comprising an outer needle surrounding a finer gauge needle which, after percutaneous penetration by the outer needle, extends to penetrate the intervertebral disc into which the injectable is to be delivered.

Abstract: A pre-assembled, telescoping needle system comprising an outer needle surrounding a finer gauge needle which, after percutaneous penetration by the outer needle, extends to penetrate the intervertebral disc into which the injectable is to be delivered.

Abstract: A pre-assembled, telescoping needle system comprising an outer needle surrounding a finer gauge needle which, after percutaneous penetration by the outer needle, extends to penetrate the intervertebral disc into which the injectable is to be delivered.

Abstract: A method of irradiating spinal tissue with red light, comprising: inserting a cannulated device defining a bore into the spinal column, wherein the bore contains an optically transparent substrate adapted to emit red light, and transmitting red light through the substrate to intermittently irradiate tissue within the spinal column.

Abstract: A method of irradiating spinal tissue with red/NIR light, comprising: inserting a cannulated device defining a bore into the spinal column, wherein the bore contains an optically transparent substrate adapted to emit red/NIR light, and transmitting NIR/red light through the substrate to irradiate tissue within the spinal column.

Abstract: Disclosed herein is a method of treating a patient that involves injecting a flowable material into a cancellous bone region of a bone, wherein the material is adapted to facilitate tissue regeneration, and then irradiating the cancellous bone region with an effective amount of NIR/red light. The irradiation may be carried out from a light source located inside the bone. The light may enter the bone via a transmitter located underneath the skin of the patient.

Abstract: A covering for delivering a substance or material to a surgical site is provided. The covering, with substance provided therein, may be referred to as a delivery system. Generally, the covering may be a single or multi-compartment structure capable of at least partially retaining a substance provided therein until the covering is placed at a surgical site. Upon placement, the covering may facilitate transfer of the substance or surrounding materials. For example, the substance may be released (actively or passively) to the surgical site. The covering may participate in, control, or otherwise adjust, the release of the substance.

Abstract: The present invention relates to injecting a high specificity cytokine antagonist into a diseased intervertebral disc.

Abstract: The present invention relates to injecting a high specificity cytokine antagonist into a diseased intervertebral disc.

Abstract: A method of irradiating spinal tissue with red/NIR light, comprising: inserting a cannulated device defining a bore into the spinal column, wherein the bore contains an optically transparent substrate adapted to emit red/NIR light, and transmitting NIR/red light through the substrate to irradiate tissue within the spinal column.

Abstract: The present invention relates to injecting a high specificity cytokine antagonist into a diseased intervertebral disc.

Abstract: The present invention relates to injecting a high specificity cytokine antagonist into a diseased intervertebral disc.

Abstract: The present invention relates to injecting a high specificity cytokine antagonist into a diseased intervertebral disc.

Abstract: The present invention relates to injecting a high specificity cytokine antagonist into a diseased intervertebral disc.

Abstract: The present invention relates to injecting a high specificity cytokine antagonist into a diseased intervertebral disc.

Abstract: The present invention relates to injecting a high specificity cytokine antagonist into a diseased intervertebral disc.

Abstract: Red light implants for delivering red light to spinal implants to enhance osteointegration.

Abstract: An intracranial, light-emitting implant for providing therapy to a patient having Alzheimer's Disease.

Abstract: This invention relates to local administration of a bone-forming agent and at least one anti-resorptive agent to treat osteoporosis and related disorders.