Patents by Inventor Mohamed Attawia

Mohamed Attawia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transdiscal administration of cycline compounds
    Publication number: 20050038001
    Abstract: The present invention relates to injecting a cycline compound into a diseased intervertebral disc.
    Type: Application
    Filed: August 13, 2003
    Publication date: February 17, 2005
    Applicant: DePuy Spine, Inc.
    Inventors: Mohamed Attawia, Thomas DiMauro, Hassan Serhan, Melissa Grace, Sudhakar Kadiyala, David Urbahns, Scott Bruder, Gregory Collins, Laura Brown, Jeff Geesin, Pamela Plouhar, Catherine Smith, John Siekierka
  • Trans-capsular administration of high specificity cytokine inhibitors into orthopedic joints
    Publication number: 20050025765
    Abstract: The present invention relates to trans-capsularly administering into a diseased joint a high specificity antagonist selected from the group consisting of: i) an inhibitor of a pro-inflammatory interleukin; ii) an inhibitor of TNF-? synthesis; iii) an inhibitor of membrane-bound TNF-?; iv) an inhibitor of a natural receptor of TNF-?; v) an inhibitor of NO synthase, vi) an inhibitor of PLA2 enzyme; vii) an anti-proliferative agent; viii) an anti-oxidant; ix) an apoptosis inhibitor selected from the group consisting of EPO mimetic peptides, EPO mimetibodies, IGF-I, IGF-II, and caspase inhibitors, and x) an inhibitor of MMPs; and xi) an inhibitor of p38 kinase.
    Type: Application
    Filed: July 30, 2003
    Publication date: February 3, 2005
    Applicant: DePuy Spine, Inc.
    Inventors: Thomas DiMauro, Mohamed Attawia, Hassan Serhan, Martin Reynolds, Melissa Grace, Sudhakar Kadiyala, David Urbahns, Scott Bruder, Gregory Collins, Laura Brown, Jeff Geesin, Pamela Plouhar, Catherine Smith, John Siekierka
  • Transdiscal administration of specific inhibitors of P38 kinase
    Publication number: 20040229878
    Abstract: The present invention relates to injecting a high specificity p38 kinase inhibitor into a diseased intervertebral disc.
    Type: Application
    Filed: July 31, 2003
    Publication date: November 18, 2004
    Applicant: DePuy Spine, Inc.
    Inventors: Thomas M. DiMauro, Hassan Serhan, Mohamed Attawia, Melissa Grace, Sudhakar Kadiyala, David Urbahns, Scott Bruder, Gregory Collins, Laura J. Brown, Jeff Geesin, Pamela L. Plouhar, Catherine Smith, John Siekierka
  • Autologous treatment of degenerated disc with cells
    Publication number: 20040229786
    Abstract: The present invention relates to administering autologous uncultured cells into a diseased intervertebral disc.
    Type: Application
    Filed: November 14, 2003
    Publication date: November 18, 2004
    Applicant: DePuy Spine, Inc.
    Inventors: Mohamed Attawia, Hassan Serhan, Thomas M. DiMauro, Melissa Grace, David Urbahns
  • Transdiscal administration of high affinity anti-MMP inhibitors
    Publication number: 20040228853
    Abstract: The present invention relates to injecting a high affinity antagonist of MMPs into a diseased intervertebral disc.
    Type: Application
    Filed: June 30, 2003
    Publication date: November 18, 2004
    Applicant: DePuy Spine, Inc.
    Inventors: Hassan Serhan, Thomas M. DiMauro, Mohamed Attawia, Melissa Grace, Sudhakar Kadiyala, David Urbahns, Scott Bruder, Gregory Collins
  • Muscle-polymer constructs for bone tissue engineering
    Publication number: 20040115238
    Abstract: Bone grafting materials containing a polymer scaffold loaded with bone morphogenetic proteins and populated with muscle cells induced by the bone morphogenetic proteins to exhibit an osteoblastic phenotype and to synthesize bone tissue are provided. Also provided are methods for using these polymer scaffolds in bone grafting procedures.
    Type: Application
    Filed: January 28, 2004
    Publication date: June 17, 2004
    Inventors: Cato T. Laurencin, Helen H. Lu, Michelle D. Kofron, Saadiq El-Amin, Mohamed A. Attawia