Abstract: Provided herein are nanobubbles designed for use in ultrasound-mediated ablation of cancer cells. The nanobubbles undergo ultrasound-mediated cavitation at an ablation threshold which is significantly decreased, relative to standard ultrasound-mediated treatment of cancer cells. In exemplary embodiments, the nanobubbles comprise an amphiphilic ABC triblock copolymer, wherein block A comprises a hydrophilic polymer, block B comprises a crosslinking polymer, and block C comprises a hydrophobic copolymer comprising (i) methyl methacrylate (MMA) and (ii) a fluorinated monomer, wherein the fluorinated monomer is present in the hydrophobic copolymer of block C at 25 mole percent or less. Related treatment and diagnostic methods, as well as materials relating to the nanobubbles are provided herein. Methods of making a random copolymer are furthermore provided herein.

Abstract: Provided herein are nanobubbles designed for use in ultrasound-mediated ablation of cancer cells. The nanobubbles undergo ultrasound-mediated cavitation at an ablation threshold which is significantly decreased, relative to standard ultrasound-mediated treatment of cancer cells. In exemplary embodiments, the nanobubbles comprise an amphiphilic ABC triblock copolymer, wherein block A comprises a hydrophilic polymer, block B comprises a crosslinking polymer, and block C comprises a hydrophobic copolymer comprising (i) methyl methacrylate (MMA) and (ii) a fluorinated monomer, wherein the fluorinated monomer is present in the hydrophobic copolymer of block C at 25 mole percent or less. Related treatment and diagnostic methods, as well as materials relating to the nanobubbles are provided herein. Methods of making a random copolymer are furthermore provided herein.

Abstract: The present invention relates to devices, systems and methods for measuring cell barrier function. In particular, the present invention relates to microfluidic devices for use in in vitro models of the blood-brain barrier and modeling the transport across this barrier.

Abstract: The present invention provides a method of operating a set-top box that is coupled to a video display, the set-top box being configured for communication with a video content provider. One embodiment of the method may include initiating display of a first portion of video content that is pre-loaded onto the set-top box and transmitting a request to subscribe to a first multicast service in response to initiating display of the first portion of the video content. The video content provider is configured to provide a second portion of the video content using the first multicast service.

Abstract: Embodiments are described herein to provide a general approach to wireless outage recovery. One general approach involves network equipment detecting (101) an outage condition for a wireless coverage area. In response to detecting the outage condition, the network equipment adjusts (102) a tilt setting of an antenna at a wireless node having a neighboring wireless coverage area. The wireless node then provides (103) wireless service to at least a portion of the wireless coverage area to mitigate the outage condition. Ideally, the wireless node provides wireless service to one or more areas of high traffic density within the outage area.

Abstract: A network design method for Ethernet-type networks exhibiting capacities sufficient for operation during normal periods as well those as periods when a single node or link has failed.

Abstract: A network design method for Ethernet-type networks exhibiting capacities sufficient for operation during normal periods as well those as periods when a single node or link has failed.

Abstract: The present invention provides a method of operating a set-top box that is coupled to a video display, the set-top box being configured for communication with a video content provider. One embodiment of the method may include initiating display of a first portion of video content that is pre-loaded onto the set-top box and transmitting a request to subscribe to a first multicast service in response to initiating display of the first portion of the video content. The video content provider is configured to provide a second portion of the video content using the first multicast service.

Abstract: A vertical axis wind system is provided including a center post assembly, a power generation system, a blade attachment assembly and a blade assembly. The center post assembly includes an outer rotor rotatably connected to an inner post. The outer rotor is connected to a generator rotor for the power generation system. The blade assembly includes a plurality of blades that are attached to the outer rotor using the blade attachment assembly.

Abstract: The invention includes a method for determining an expenditure associated with a network. A method includes obtaining network information associated with a portion of a network, categorizing each of a respective plurality of cells as one of an aggregated cell and a non-aggregated cell, determining an aggregating node configuration for at least one aggregating node associated with at least one base station associated with an aggregated cell, determining a deaggregating node configuration for at least one deaggregating node associated with at least one of the at least one aggregating node, and determining the expenditure according to at least one of the aggregating node configuration and the deaggregating node configuration. The categorization of cells is performed using the network information.

Abstract: A seat belt buckle receptacle presenter is disclosed that presents the seat belt buckle receptacle to a vehicle occupant in a convenient and visually accessible location. In a first preferred embodiment, the seat belt receptacle is pivotally mounted along a generally horizontal track to move from a storage position located in the rearward portion of a vehicle seat to a presenting position located adjacent a forward edge of the vehicle seat. An alternative second preferred embodiment includes an upwardly extending presenting arm that is connected to a conventional restraint belt receptacle. The presenting arm receives a seat belt buckle and delivers the belt buckle to the seat belt receptacle.

Abstract: A restraint belt presenter assembly includes a restraint belt engaging member that is selectively driven by a track drive mechanism to catch and pull a restraint belt from its unused position to a presentation position for grasping by a vehicle occupant. In one embodiment, the restraint belt engaging member includes a selectively upwardly moving arm having a finger assembly with an offset rotary action for moving the finger assembly into an actuating position. In a second embodiment, the restraint belt engaging member is connected to a hinge member that pivots the restraint belt engaging member into an actuating position.

Abstract: A restraint belt presenter assembly includes a restraint belt positioning member carried by a slidable member that is selectively driven by a track drive mechanism to move a restraint belt buckle assembly forward from its unused, storage position to a presentation position for easy grasping by a vehicle seat occupant. The slidable member is connected to a track that may optionally be pivotally mounted to elevate the restraint belt positioning member into the presentation position. Alternatively, the track member may include an inclined distal end, such that the slidable member moves upwardly into the presentation position. Another embodiment includes a pivoting shaft member that pivots the restraint belt buckle assembly forward for a starting position to the presentation position as the slidable member travel upwardly on an inclined track.

Abstract: A restraint presentation system is disclosed that includes a movable presenting member, such as an armrest or an actuating arm, that moves between a presenting position and a storage position and a restraint belt connected to a tensioning mechanism. The presenting member preferably has a concave shaped portion on a distal end thereof that captures a contact portion of the restraint belt to position the restraint belt in an operational position so as to be accessible to a vehicle occupant. The tensioning mechanism biases the restraint belt into a retracted position when the presenting member is in the storage position such that the contact portion of the restraint belt is in a co-linear relationship with the concave shaped portion of the presenting member.

Abstract: A restraint presentation system is disclosed that includes a movable presenting member, such as an armrest or an actuating arm, that moves between a presenting position and a storage position and a restraint belt connected to a tensioning mechanism. The presenting member preferably has a concave shaped portion on a distal end thereof that captures a contact portion of the restraint belt to position the restraint belt in an operational position so as to be accessible to a vehicle occupant. The tensioning mechanism biases the restraint belt into a retracted position when the presenting member is in the storage position such that the contact portion of the restraint belt is in a co-linear relationship with the concave shaped portion of the presenting member.

Abstract: A vehicle component sub-assembly having self-aligning appropriately fitted structural members is disclosed wherein a closure member, such as a vehicle door, hood or trunk is integrated with and becomes a structural part of a vehicle body. The sub-assembly includes mating components wherein a first mating component is mounted to the vehicle body and a second mating component is mounted to the closure member in such a manner that the first and second mating components become substantially aligned and structurally engaged with one another. The first mating component includes at least one structural key member formed thereon and the second mating component has a complementary mating receptacle therein. When the first and second mating components are aligned into interlocking engagement, the structural key members and mating receptacles are thereby structurally integrating the vehicle body and the closure member.

Abstract: A vehicle closure panel includes an outer frame that is connected to a central beam portion to provide a primary structure that resists deformation and efficiently distributes impact forces during a collision. The present invention can be used with or without structural key members and mating recesses to integrate the closure panel with the rest of the vehicle body, depending on design criteria. Also, primary structure of the present invention provides a structural modularity for closure panels that simplifies design by reducing the number of overall parts and uses the primary structure alone to meet the demands for crash testing. Thus, a basic structure is relied on for crash strength while accompanying secondary structures provide cosmetic differences.

Abstract: A vehicle seat includes a generally horizontal sitting portion connected to a generally vertical backrest, and an armrest connected to the sitting portion or the armrest. At least one of the sitting portion, the backrest, or the armrest includes a plastically deformable cellular structural material arranged therein. Another embodiment is an armrest for a vehicle seat including an elastically deformable cushion material and a plastically deformable cellular structural material. A further embodiment is a vehicle seat including a sitting portion connected to a backrest, and an armrest connected to at least one of the sitting portion and the backrest. The armrest includes an elastically deformable cushion material and a plastically deformable cellular structural material. A variation of the armrest includes a barrier interposed between the cushion material and the cellular structural material. The sitting portion and the backrest each include plastically deformable cellular structural material arranged therein.