Patents by Inventor Mohamed Ismail

Mohamed Ismail has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

Wireless communications apparatus

Publication number: 20070079213

Abstract: Wireless transmission of data is effected across a communications channel defined by a communications medium by means of an encoder, operable to apply a low density parity check (LDPC) code to data for transmission. The LDPC code is irregular with respect to the degree of variable nodes, and so the transmitter further comprises means for sorting encoded data with respect to the corresponding variable node degree, and modulation and distribution means for allocating encoded and sorted data onto the communications medium.

Type: Application

Filed: June 28, 2006

Publication date: April 5, 2007

Applicant: Kabushiki Kaisha Toshiba

Inventor: Mohamed Ismail
Novel bichalcophenes and their prodrugs as antiprotozoal agents

Publication number: 20060293540

Abstract: Novel dicationic bichalcophene compounds are described. The presently disclosed novel dicationic bichalcophene compounds exhibit in vitro activity versus Trypanosoma brucei rhodesiense, Plasmodium falciparum, or Leishmania donovani comparable to that of pentamidine and furamidine. Some of the novel dicationic bichalcophene compounds displayed good activity in vivo in a murine model of a Trypanosoma brucei rhodesiense infection.

Type: Application

Filed: May 16, 2006

Publication date: December 28, 2006

Inventors: Richard Tidwell, David Boykin, Chad Stephens, Mohamed Ismail, W. Wilson, Reto Brun, Karl Werbovetz
Linear dicationic terphenyls and their aza analogues as antiparasitic agents

Publication number: 20060293328

Abstract: Novel dicationic terphenyl compounds and their aza analogues. Methods for combating microbial infections with novel dicationic terphenyl compounds and their aza analogues. Processes for synthesizing novel dicationic terphenyl compounds and their aza analogues.

Type: Application

Filed: May 17, 2006

Publication date: December 28, 2006

Inventors: Richard Tidwell, David Boykin, W. Wilson, Reto Brun, Karl Werbovetz, Mohamed Ismail, Reem Arafa
11a, 12-derivatives of tetracycline compounds

Publication number: 20060281717

Abstract: 11a, 12-dehydrotetracycline compounds are described.

Type: Application

Filed: February 6, 2006

Publication date: December 14, 2006

Inventors: Joel Berniac, Mohamed Ismail, Mark Nelson, Faye Seyedi
7-Phenyl-substituted tetracycline compounds

Publication number: 20060205698

Abstract: 7-phenyl-substituted tetracycline compounds which are substantially free of positional isomers, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7-phenyl-substituted tetracycline compounds are described. 7-substituted tetracycline compounds which are substantially free of positional isomers, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7-substituted tetracycline compounds are described.

Type: Application

Filed: December 15, 2005

Publication date: September 14, 2006

Applicant: Trustees of Tufts College

Inventors: Mark Nelson, Mohamed Ismail
Substituted tetracycline compounds

Publication number: 20060166945

Abstract: The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.

Type: Application

Filed: October 25, 2005

Publication date: July 27, 2006

Applicant: Paratek Pharmaceuticals, Inc.

Inventors: Paul Abato, Haregewein Assefa, Joel Berniac, Beena Bhatia, Todd Bowser, Jackson Chen, Mark Grier, Laura Honeyman, Mohamed Ismail, Mark Nelson, Kwasi Ohemeng, Jingwen Pan
3, 10, and 12a Substituted tetracycline compounds

Publication number: 20050288262

Abstract: The present invention pertains to novel 3, 10, and/or 12a-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.

Type: Application

Filed: February 28, 2005

Publication date: December 29, 2005

Applicant: Paratek Pharmaceuticals, Inc.

Inventors: Upul Bandarage, Jackson Chen, Mohamed Ismail, Mark Nelson, Kwasi Ohemeng
Novel dicationic imidazo[1,2-a]pyridines and 5,6,7,8,-tetrahydro-imidazo[1,2,-a]pyridines as antiprotozoal agents

Publication number: 20050282853

Abstract: A method for treating a microbial infection, including an infection from a protozoan pathogen, such as Trypanosoma brucei rhodesiense and Plasmodium falciparum, in a subject in need thereof by administering to the subject an effective amount of a dicationic imidazopyridine compound or a dicationic tetrahydro-imidazopyridine compound. Processes for synthesizing dicationic imidazopyridines and dicationic tetrahydro-imidazopyridines and the novel dicationic imidazopyridine and dicationic tetrahydro-imidazopyridine compounds themselves.

Type: Application

Filed: March 8, 2005

Publication date: December 22, 2005

Inventors: David Boykin, Richard Tidwell, W. Wilson, Mohamed Ismail
Channel estimation in a CDMA receiver

Publication number: 20050213529

Abstract: A receiver for receiving a CDMA signal comprises a common channel interference cancellation facility operable to cancel common channel interference by applying a common channel interference estimate to the received signal through a weighted hybrid of parallel and serial interference cancellation, and a physical channel self-interference cancellation facility operable to cancel physical channel self-interference by applying an interference estimate to the received signal through a weighted hybrid of parallel and serial interference cancellation.

Type: Application

Filed: January 13, 2005

Publication date: September 29, 2005

Applicant: KABUSHIKI KAISHA TOSHIBA

Inventors: Yuk Chow, Michael Fitton, Khurram Rizvi, Mohamed Ismail, Yan Bian
Dicationic triaryl analogs as anti-protozoan agents

Publication number: 20050148646

Abstract: Novel dicationic, heterocyclic triaryl compounds are useful in the treatment of microbial infections, such as Trypanosoma brucei rhodesiense infection and Plasmodium falciparum infection. These compounds are accordingly useful in treating second-stage human African trypanosomiasis. Pharmaceutical formulations comprising these compounds can be used in methods of treating microbial infections.

Type: Application

Filed: October 25, 2004

Publication date: July 7, 2005

Inventors: David Boykin, Richard Tidwell, W. David Wilson, Reto Brun, Mohamed Ismail
Substituted tetracycline compounds

Publication number: 20050143352

Abstract: The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.

Type: Application

Filed: June 25, 2004

Publication date: June 30, 2005

Applicant: Paratek Pharmaceuticals, Inc.

Inventors: Mark Nelson, Kwasi Ohemeng, Paul Abato, Victor Amoo, Haregewein Assefa, Joel Berniac, Beena Bhatia, Todd Bowser, Jackson Chen, Mark Grier, Laura Honeyman, Mohamed Ismail, Oak Kim, Jude Mathews, Rachid Mechiche
Substituted tetracycline compounds

Publication number: 20050038002

Abstract: The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.

Type: Application

Filed: December 18, 2003

Publication date: February 17, 2005

Applicant: Paratek Pharmaceuticals, Inc.

Inventors: Mark Nelson, Kwasi Ohemeng, Roger Frechette, Paul Abato, Victor Amoo, Upul Bandarage, Joel Berniac, Beena Bhatia, Jackson Chen, Mohamed Ismail, Oak Kim, Laura Honeyman, Rachid Mechiche, Andre Pearson, Laxma Nagavelli, Paul Sheahan, Atul Verma, Peter Viski, Tadeusz Warchol
Amino-methyl substituted tetracycline compounds

Publication number: 20050026875

Abstract: Aminomethyl substituted tetracycline compounds, pharmaceutical compositions, and methods of use thereof are discussed.

Type: Application

Filed: December 15, 2003

Publication date: February 3, 2005

Applicant: Paratek Pharmaceuticals, Inc.

Inventors: Mark Nelson, Kwasi Ohemeng, Roger Frechette, Paul Abato, Victor Amoo, Haregewein Assefa, Joel Berniac, Beena Bhatia, Todd Bowser, Jackson Chen, Laura Honeyman, Mohamed Ismail, Oak Kim, Rachid Mechiche, N. Reddy, Atul Verma, Peter Viski, Tadeusz Warchol, Ivan Yanachkov
9-aminomethyl substituted minocycline compounds

Publication number: 20050026876

Abstract: The present invention pertains, at least in part, to novel 9-substituted minocycline compounds. These minocycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and minocycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.

Type: Application

Filed: February 24, 2004

Publication date: February 3, 2005

Inventors: Mark Nelson, Roger Frechette, Mohamed Ismail, Laura Honeyman, Todd Bowser, Beena Bhatia
7-Substituted tetracycline compounds

Publication number: 20040224928

Abstract: The present invention pertains, at least in part, to novel 7-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.

Type: Application

Filed: May 24, 2004

Publication date: November 11, 2004

Applicants: Trustees of Tufts College, Paratek Pharmaceuticals, Inc.

Inventors: Mark L. Nelson, Roger Frechette, Peter Viski, Mohamed Ismail, Todd Bowser, Beena Bhatia, David Messersmith, Laura McIntyre, Darrell Koza, Glen Rennie, Paul Sheahan, Paul Hawkins, Atul Verma, Tadeusz Warchol, Upul Bandarage
9-Substituted minocycline compounds

Publication number: 20040214801

Abstract: The present invention pertains, at least in part, to novel 9- substituted minocycline compounds. These minocycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.

Type: Application

Filed: May 4, 2004

Publication date: October 28, 2004

Applicants: Paratek Pharmaceuticals, Inc., Trustees of Tufts College

Inventors: Mark L. Nelson, Roger Frechette, Peter Viski, Mohamed Ismail, Todd Bowser, Jimmy Dumornay, Glen Rennie, Gui Liu, Darrell Koza, Paul Sheahan, Karen Stapleton, Paul Hawkins, Beena Bhatia, Atul K. Verma, Laura McIntyre, Tadeusz Warchol, David Messersmith
7, 9-substituted tetracycline compounds

Patent number: 6683068

Abstract: The present invention pertains to novel 7,9-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.

Type: Grant

Filed: June 29, 2001

Date of Patent: January 27, 2004

Assignee: Paratek Pharmaceuticals, Inc.

Inventors: Mark L. Nelson, Roger Frechette, Peter Viski, Mohamed Ismail, Todd Bowser, Laura McIntyre, Beena Bhatia, Paul Hawkins, Laxma Reddy, Karen Stapleton, Tad Warchol, Paul Sheahan
9-substituted minocycline compounds

Publication number: 20030125348

Abstract: The present invention pertains, at least in part, to novel 9-substituted minocycline compounds. These minocycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.

Type: Application

Filed: June 29, 2001

Publication date: July 3, 2003

Inventors: Mark L. Nelson, Roger Frechette, Peter Viski, Mohamed Ismail, Todd Bowser, Jimmy Dumornay, Glen Rennie, Gui Liu, Darrell Koza, Paul Sheahan, Karen Stapleton, Paul Hawkins, Beena Bhatia, Atul K. Verma, Laura McIntyre, Tadeusz Warchol, David Messersmith
7-substituted tetracycline compounds

Publication number: 20030055025

Abstract: The present invention pertains, at least in part, to novel 7-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.

Type: Application

Filed: June 29, 2001

Publication date: March 20, 2003

Inventors: Mark L. Nelson, Roger Frechette, Peter Viski, Mohamed Ismail, Todd Bowser, Beena Bhatia, David Messersmith, Laura McIntyre, Darrell Koza, Glen Rennie, Paul Sheahan, Paul Hawkins, Atul Verma, Tadeusz Warchol, Upul Bandarage
7, 9-substituted tetracycline compounds

Publication number: 20020193354

Abstract: The present invention pertains to novel 7,9-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.

Type: Application

Filed: June 29, 2001

Publication date: December 19, 2002

Inventors: Mark L. Nelson, Roger Frechette, Peter Viski, Mohamed Ismail, Todd Bowser, Laura McIntyre, Beena Bhatia, Paul Hawkins, Laxma Reddy, Karen Stapleton, Tad Warchol, Paul Sheahan

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