Abstract: Methods for treating moderate-to-severe or severe atopic dermatitis in a pediatric subject are provided. In one aspect, the methods comprise administering to the subject one or more doses of an interleukin-4 receptor (IL-4R) antagonist, such as an anti-IL-4R antibody or antigen-binding fragment thereof.

Abstract: Systems and techniques for retrieving video data associated with a selected attribute are described. The systems and techniques include receiving a multimodal input associated with the attribute for querying a catalog of video data to identify video data including the attribute. A first embedding is determined for the input using a first encoder to map the input to a representation space. A second embedding is determined for the video data to map the video data to the representation space. A similarity score is determined between the video data and the input based on a distance between the embeddings. The video data associated with the attribute may be selected based on the similarity score.

Abstract: Methods for treating moderate-to-severe or severe atopic dermatitis in a pediatric subject are provided. In one aspect, the methods comprise administering to the subject one or more doses of an interleukin-4 receptor (IL-4R) antagonist, such as an anti-IL-4R antibody or antigen-binding fragment thereof.

Abstract: Techniques are disclosed for detecting an uncovered portion of a body of a person in a frame of video content. In an example, a first machine learning model of a computing system may output a first score for the frame based on a map that identifies a region of the frame associated with an uncovered body part type. Depending on a value of the first score, a second machine learning model that includes a neural network architecture may further analyze the frame to output a second score. The first score and second score may be merged to produce a third score for the frame. A plurality of scores may be determined, respectively, for frames of the video content, and a maximum score may be selected. The video content may be selected for presentation on a display for further evaluation based on the maximum score.

Abstract: A system can be utilized to retrieve media content and rating schemas, to determine maturity ratings for media content. The media content can be utilized to determine segments of data as building blocks associated with mature content. The building blocks can be mapped to content descriptors and rating levels associated with the rating schemas. The building blocks can be compared the media content to identify portions of the media content that have characteristics represented by the building blocks. The building blocks representing the characteristics in the portions of the media content can be utilized to select content descriptors and rating levels associated with the media content. The selected content descriptor and selected rating levels can be utilized to control how, and/or whether, the media content is made available for output to the consumers.

Abstract: Techniques are disclosed for detecting an uncovered portion of a body of a person in a frame of video content. In an example, a first machine learning model of a computing system may output a first score for the frame based on a map that identifies a region of the frame associated with an uncovered body part type. Depending on a value of the first score, a second machine learning model that includes a neural network architecture may further analyze the frame to output a second score. The first score and second score may be merged to produce a third score for the frame. A plurality of scores may be determined, respectively, for frames of the video content, and a maximum score may be selected. The video content may be selected for presentation on a display for further evaluation based on the maximum score.

Abstract: Methods for treating eosinophilic esophagitis in a pediatric subject are provided. In one aspect, the methods comprise administering to the subject one or more doses of an interleukin-4 receptor (IL-4R) antagonist, such as an anti-IL-4R antibody or antigen-binding fragment thereof.

Abstract: Methods for treating moderate-to-severe atopic dermatitis in a pediatric subject are provided. In one aspect, the methods comprise administering to the subject one or more doses of an interleukin-4 receptor (IL-4R) antagonist, such as an anti-IL-4R antibody or antigen-binding fragment thereof.

Abstract: Methods for treating moderate-to-severe atopic dermatitis in a pediatric subject are provided. In one aspect, the methods comprise administering to the subject one or more doses of an interleukin-4 receptor (IL-4R) antagonist, such as an anti-IL-4R antibody or antigen-binding fragment thereof.

Abstract: Techniques are disclosed for detecting a type of prurient activity shown by a portion of video content. In an example, a machine learning model of a computer system may receive a second portion of video content, the machine learning model including a neural network that is trained to analyze a temporal dimension of the second portion. The machine learning model determines a score indicating a likelihood that the video content shows the type of prurient activity based in part on applying a three-dimensional filter to the second portion of the video content. The computer system then generates a video clip that includes at least the portion of the video content showing the type of prurient activity based on the score, and provides the video clip for display.

Abstract: A closed dual-bladder wave energy system that is capable of capturing a continuous supply of energy derived from wave movements for nearshore implementations. Rather than employing an onshore bladder in communication with an offshore bladder, and rather than focusing on capturing more incremental potential energy derived from tidal movement, the system accomplishes continuous captures potential energy from waves via a dual-bladder system employed offshore. Fluid within the system translates between a first offshore bladder and a second offshore bladder based on a pressure differential between a crest and a trough of a wave external to the system. By utilizing compliant bladders, the system is capable of capturing energy even during inclement weather conditions without the risk of faults resulting from strong waves. As such, the system provides for the efficient and effective capture of potential energy from waves in any weather condition and in any water environment that experiences waves.

Abstract: A wave energy collection and conversion system that uses a compliant capture mechanism to enable the collection of wave energy over extensive distances without introducing damaging forces onto the collection structure. The system includes a flexible membrane in contact with or submerged under water, a plurality of power generation devices positioned on a sea floor, and lines that connect the flexible membrane to the power generation devices. The power generation devices each include a self-reeling mechanism and a turbine. As wave energy pushes the flexible membrane, the lines are reeled into and out of the corresponding power generation device(s). Rotation of the shaft, in turn, rotates a gear and rotator of the turbine, thus harnessing energy derived from the wave motion.

Abstract: Methods for treating moderate-to-severe or severe atopic dermatitis in a pediatric subject are provided. In one aspect, the methods comprise administering to the subject one or more doses of an interleukin-4 receptor (IL-4R) antagonist, such as an anti-IL-4R antibody or antigen-binding fragment thereof.

Abstract: This invention relates to an asymmetric composite membrane containing a polymeric matrix and carbon nanotubes within a single membrane layer, where the carbon nanotubes are randomly oriented within the polymeric matrix and the composite membrane is formed by phase inversion. This invention also relates to a method for producing the composite membrane which includes: coating a surface with a film of a polymer solution containing a polymeric matrix and carbon nanotubes dissolved in at least one solvent; immersing the coated surface in a non-solvent to affect solvent/non-solvent demixing resulting in phase inversion to form a carbon nanotube-containing membrane; and optionally, removing the carbon nanotube-containing membrane from the surface. The invention also relates to a desalination method using the composite membrane.

Abstract: A wave energy collection and conversion system that uses a compliant capture mechanism to enable the collection of wave energy over extensive distances without introducing damaging forces onto the collection structure. The system includes a flexible membrane in contact with or submerged under water, a plurality of power generation devices positioned on a sea floor, and lines that connect the flexible membrane to the power generation devices. The power generation devices each include a self-reeling mechanism and a turbine. As wave energy pushes the flexible membrane, the lines are reeled into and out of the corresponding power generation device(s). Rotation of the shaft, in turn, rotates a gear and rotator of the turbine, thus harnessing energy derived from the wave motion.

Abstract: A closed system that captures energy derived from the head differential rather than open-water flows velocities while reducing potential environmental damages and costly maintenance due to bio-fouling. This energy density available in a tidal range is increased substantially via convergent “nozzles” to produce an optimal speed for power generations with the turbine sections, thereby significantly increasing the tidal energy captured by this system, even at sites where tidal energy is low (e.g., small to medium tide ranges, such as found along the East and Gulf Coasts of the United States).

Abstract: A closed system that captures energy derived from the head differential rather than open-water flows velocities while reducing potential environmental damages and costly maintenance due to bio-fouling. This energy density available in a tidal range is increased substantially via convergent “nozzles” to produce an optimal speed for power generations with the turbine sections, thereby significantly increasing the tidal energy captured by this system, even at sites where tidal energy is low (e.g., small to medium tide ranges, such as found along the East and Gulf Coasts of the United States).

Abstract: The invention provides a sensing device that can be incorporated in a construction element for a toy construction set to allow new use of construction elements, for instance tracking the construction process. Sensing device comprises a carrier comprising a top surface provided with a series of top coils, a bottom surface with a series of bottom coils at a distance from said top coils, the sensing device further comprising a data processor functionally coupled with a memory for storing a status, said data processor comprises a computer program which controls and reads currents through each of said top and bottom coils and storing them in memory, thereby tracking status for each of said top and bottom coils.

Abstract: The invention provides a sensing device that can be incorporated in a construction element for a toy construction set to allow new use of construction elements, for instance tracking the construction process. Sensing device comprises a carrier comprising a top surface provided with a series of top coils, a bottom surface with a series of bottom coils at a distance from said top coils, the sensing device further comprising a data processor functionally coupled with a memory for storing a status, said data processor comprises a computer program which controls and reads currents through each of said top and bottom coils and storing them in memory, thereby tracking status for each of said top and bottom coils.

Abstract: The invention provides a sensing device that can be incorporated in a construction element for a toy construction set to allow new use of construction elements, for instance tracking the construction process. Sensing device comprises a carrier comprising a top surface provided with a series of top coils, a bottom surface with a series of bottom coils at a distance from said top coils, the sensing device further comprising a data processor functionally coupled with a memory for storing a status, said data processor comprises a computer program which controls and reads currents through each of said top and bottom coils and storing them in memory, thereby tracking status for each of said top and bottom coils.