Patents by Inventor Mohamed M. Rafi

Mohamed M. Rafi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sorghum Extract Compositions
    Publication number: 20080241282
    Abstract: Methods and compositions for preventing or treating various diseases or conditions in a patient with an alcohol extractable fraction of Sorghum bicolor grain.
    Type: Application
    Filed: June 21, 2007
    Publication date: October 2, 2008
    Applicant: RUTGERS, THE STATE UNIVERSITY
    Inventors: Mohamed M. Rafi, Thomas G. Hartman, Yesu T. Das, Yassaman Shafaie, John Hargreaves
  • Antioxidant and anti-inflammatory activity of compounds and preparations from African nutmeg seeds
    Patent number: 7371413
    Abstract: The present invention provides methods for reducing the production of nitric oxide, inducible nitric oxide synthase protein and mRNA, and cyclooxygenase-2 protein and mRNA in cells both in vivo and in vitro via the administration of extracts and compounds derived from the seeds of Pycnanthus angolensis Warb. (P. Kombo), commonly known as African nutmeg. These extracts and compounds, namely, kombo butter, kombo butter acid extract, sargaquinoic acid, sargachromenol, and sargahydroquinoic acid, are also useful in the treatment and prevention of a battery of adverse health conditions in human, animal, and avian subjects that are advanced by the production of nitric oxide or its metabolites and/or by the activity of cyclooxygenase-2. Methods for the isolation of kombo butter acid extracts are also provided.
    Type: Grant
    Filed: May 5, 2004
    Date of Patent: May 13, 2008
    Assignees: Rutgers, The State University, BioResources International Inc.
    Inventors: James E. Simon, Mingfu Wang, Kodzo Gbewonyo, Mohamed M. Rafi, Daniel Fahene Acquaye, Yaw Asianowa
  • Use of 1-propanone-1-(2,4-dihydroxyphenyl)-3-hydroxy-3-(4?-hydroxyphenyl) as an anticarcinogenic agent
    Patent number: 6498195
    Abstract: Compositions and methods are provided for prevention and treatment of cancer. The compositions comprise pure hydroxylated chalcone compounds of licorice root (Glycyrrhiza glabra) including 1-propanone-1-(2,4-dihydroxyphenyl)-3-hydroxy-3-(4′-hydroxyphenyl).
    Type: Grant
    Filed: June 13, 2001
    Date of Patent: December 24, 2002
    Assignees: Rutgers, The State University of New Jersey, University of Medicine and Dentistry of New Jersey
    Inventors: Robert T. Rosen, Chi-Tang Ho, Robert S. DiPaola, Mohamed M. Rafi, Bret C. Vastano, Geetha Ghai
  • Anti-carcinogenic activity of hydroxylated chalcone compounds extracted from licorice root
    Publication number: 20020022665
    Abstract: Compositions and methods are provided for prevention and treatment of cancer. The compositions comprise pure hydroxylated chalcone compounds of licorice root (Glycyrrhiza glabra) including 1-propanone-1-(2,4-dihydroxyphenyl)-3-hydroxy-3-(4′-hydroxyphenyl).
    Type: Application
    Filed: June 13, 2001
    Publication date: February 21, 2002
    Inventors: Robert T. Rosen, Chi-Tang Ho, Robert S. DiPaola, Mohamed M. Rafi, Bret C. Vastano, Geetha Ghai