Abstract: A method of treating cancer can include administering one or more of the isatin derivatives to a patient in need thereof. In an embodiment, the cancer is selected from the group consisting of breast cancer, non-small cell lung cancer, renal cancer and melanoma.

Abstract: A method of treating cancer can include administering one or more of the isatin derivatives to a patient in need thereof. In an embodiment, the cancer is selected from the group consisting of breast cancer, non-small cell lung cancer, renal cancer and melanoma.

Abstract: The testing chamber for laboratory animals includes multiple testing points to provide multiple tests and testing zones within the same chamber. The testing chamber for laboratory animals provides for study, testing and assessment of cognitive and motor skills of laboratory test subjects, such as mice, rats and the like. The multiple tests performed within the testing chamber may be used for an overall characterization of the neurobehavioral activities of the test animals. The testing chamber for laboratory animals includes a housing divided into first and second zones. A beam for balance beam-style travel from the first zone to the second zone is provided. A volume of water may be contained in the first zone, and the second zone may contain platforms and ramps for the laboratory animal to travel over. A passage from the first zone to the second zone may be further provided.

Abstract: The push button operated rodent restrainer is designed to hold a rodent in position to access their tail veins during tail vein injections or for extraction of blood. The assembly includes a base rectangular platform supporting two hinged, transparent half-cylinders. When the assembly is closed, the half-cylinders form a closed tube, which restrains the rodent. The half-cylinders are made of transparent plastic to allow laboratory staff to observe the rodent. The tube facilitates restraining the rodent and includes a longitudinal slit to allow proper ventilation while the rodent is restrained. One end of the closed tube has a slot, which allows the rodent's tail to protrude outside the tube for access to the tail. A push button mounted on a resilient lever is connected to the tube halves such that when the push button is depressed, the tube opens, and when the push button is released, the tube closes.