Abstract: A method for detecting and treating lung inflammation. The method includes acquiring a sputum sample from a person suspected to have a lung inflammation, measuring a level of glucose in the sputum sample, detecting lung inflammation status of the person based on the measured level of glucose, and treating the person with a detected lung inflammation by prescribing anti-inflammatory medications to the person based on a clinician's advice. Detecting the lung inflammation status of the person includes detecting no lung inflammation if the measured level of glucose is less than a minimum threshold glucose concentration, or detecting a lung inflammation if the measured level of glucose is equal to or more than a maximum threshold glucose concentration, or detecting a probable lung inflammation if the measured level of glucose is between the minimum threshold glucose concentration and the maximum threshold glucose concentration.

Abstract: An electromechanical system for detecting cancerous state of a single cell. The electromechanical system includes an aspirating mechanism, an electrical measurement mechanism, and a processing mechanism. The aspirating mechanism is configured to extract a single cell from a suspension of a plurality of suspended biological cells, hold the extracted single cell, and apply a mechanical aspiration to the held single cell by applying a suction force to the held single cell. The electrical measurement mechanism is configured to apply a set of electrical signals to the single cell before and after applying the mechanical aspiration and measure two sets of electrical responses from the held single cell corresponding to the applied set of electrical signals before and after applying the mechanical aspiration The processing mechanism, including a data processor, configured to detect cancerous state of the single cell based on a difference between the two sets of electrical responses.

Abstract: A method for tumor suppression. The method includes inserting an active part of a wire into a cancerous tumor, electrostatically stimulating cancer cells of the cancerous tumor by injecting positive electrostatic charges to the cancer cells, and reducing size of the cancerous tumor responsive to the electrostatically stimulating cancer cells of the cancerous tumor. The active part of the wire is located at a first end of the wire. Injecting the positive electrostatic charges to the cancer cells includes accumulating the positive electrostatic charges on the inserted active part of the wire, and generating a positive electrostatic charge flow through the cancerous tumor responsive to accumulating the positive electrostatic charges on the inserted active part of the wire.

Abstract: A method for detecting cancer involved lymph nodes. The method includes placing a pH-sensing paper inside a needle of an injection syringe, filling the injection syringe with a buffer solution, putting the pH-sensing paper in contact with lymphatic fluid of a lymph node by inserting the needle of the injection syringe inside the lymph node, putting the lymphatic fluid in interaction with the buffer solution by injecting the buffer solution into the lymph node utilizing the injection syringe, and detecting that the lymph node as a cancer involved lymph node if color of the pH-sensing paper is changed to an acidic-range pH color.

Abstract: A method for targeted drug delivery. The method includes injecting a drug composition into a cancer patient's body including forming an ion of an anticancer agent of the drug composition in bloodstream of the cancer patient, placing an electrically conductive element in a region next to a tumor location inside the cancer patient's body, and delivering the drug composition to the tumor location. Delivering the drug composition to the tumor location includes electrostatically trapping the drug composition within the tumor location by applying an electrostatic field with an opposite sign of electric charge to a sign of electric charge of the ion of the anticancer agent to the electrically conductive element.

Abstract: A method for non-invasive detecting and tracing cancer.

Abstract: A method for preventing cytokine storm by suppressing clonal expansion of hyperactivated lymphocytes in a COVID-19 infected patient. The method includes placing at least four electrodes on skin of the COVID-19 infected patient by putting at least two electrodes at two locations over chest in front of ribcage of the COVID-19 infected patient and putting at least two other electrodes at two locations adjacent to lung tissue of the COVID-19 infected patient and suppressing mitosis of hyperactivated proliferative lymphocytes cells within the lung tissue of the COVID-19 infected patient by electrically stimulating the hyperactivated proliferative lymphocytes. Electrically stimulating the hyperactivated proliferative lymphocytes includes generating an alternating electric field (AEF) within the lung tissue by applying an AC voltage to the at least four electrodes and periodically changing a direction of the generated AEF in a plurality of directions within the lung tissue.

Abstract: A method for fabricating a biosensor for metastasis diagnosis. The method includes coating a photoresist layer on a substrate layer, forming a patterned region by patterning the photoresist layer utilizing a photolithography process, forming a nano-roughened patterned region by forming a plurality of nano-features on the patterned region, stripping the photoresist layer from the substrate layer, forming an array of microelectrodes and a corresponding array of electrical connections on the nano-roughened patterned region by depositing a gold/titanium (Au/Ti) bilayer on the substrate layer with the nano-roughened patterned region and forming a metastatic cell sensing trap on at least one microelectrode of the array of microelectrodes. Where, forming the metastatic cell sensing trap includes placing a solution of Human Umbilical Vein Endothelial Cells (HUVECs) on the biosensor and forcing an attachment between at least one HUVEC of the HUVECs and the at least one microelectrode on the biosensor.

Abstract: A method for detecting cancerous status of a biological sample. The method includes calculating a charge transfer resistance (Rct) of an electrochemical impedance spectroscopy (EIS) associated with lipid secretion of a biological sample, detecting a cancerous state for the biological sample responsive to the calculated Rct being equal to or more than a threshold value, and detecting a normal state for the biological sample responsive to the calculated Rct being less than the threshold value. The biological sample includes a biological sample suspected to be cancerous.

Abstract: A method for targeted drug delivery. The method includes preparing a drug composition with a surface electric charge, injecting the drug composition into a cancer patient's body, placing an electrically conductive element in a region next to a tumor location inside the cancer patient's body, and delivering the drug composition to the tumor location. Delivering the drug composition to the tumor location includes electrostatically trapping the drug composition within the tumor location by applying an electrostatic field with an opposite sign of electric charge to a sign of the surface electric charge of the drug composition to the electrically conductive element.

Abstract: An apparatus for in-vivo measuring H2O2 oxidation within a living tissue. The apparatus includes an electrochemical probe and an electrochemical stimulator-analyzer. The electrochemical probe includes a sensing part and a handle. The sensing part includes a working electrode, a counter electrode, and a reference electrode. The working electrode includes a first biocompatible conductive needle coated with a layer of vertically aligned multi-walled carbon nanotubes. The counter electrode includes a second biocompatible conductive needle. The reference electrode includes a third biocompatible conductive needle. The electrochemical stimulator-analyzer is configured to generate a set of electrical currents in a portion of the living tissue.

Abstract: A system for real-time detecting cancer by analyzing unprocessed blood. The system includes a sensor, an electrical stimulator-analyzer connected to the sensor, and a processing unit connected to the electrical stimulator-analyzer. The sensor includes three electrodes including a working electrode, a counter electrode, and a reference electrode configured to be put in contact with an unprocessed blood sample. The processing unit is configured to perform a method. The method includes applying a set of voltages between the reference electrode and the working electrode utilizing the stimulator-analyzer, measuring a produced set of currents between the counter electrode and the working electrode utilizing the stimulator-analyzer, measuring a level of a ratio of low-density neutrophils (LDNs) to high-density neutrophils (HDNs) in the unprocessed blood sample by measuring a maximum current of the measured set of currents, and detecting a cancer disease if the measured maximum current is less than a threshold value.

Abstract: A method for diagnosing COVID-19 infection of a person. The method includes acquiring a sputum sample of the person, measuring a level of reactive oxygen species (ROS) in the sputum sample, and detecting a COVID-19 infection status of the person based on the measured level of ROS. Measuring the level of ROS in the sputum sample includes recording a cyclic voltammetry (CV) pattern from the sputum sample and measuring a current peak of the recorded CV pattern. Detecting the COVID-19 infection status of the person based on the measured level of ROS includes detecting the person is infected with COVID-19 if the measured current peak is in a first range of current peaks and detecting the person is not infected with COVID-19 if the measured current peak is in a second range of current peaks.

Abstract: A biosensor for measuring an electrical response from a biological sample. The biosensor includes a substrate, a passivation layer grown on a surface of the substrate, a patterned catalyst layer deposited on the passivation layer, and three electrodes grown on the patterned catalyst layer. The three electrodes include a working electrode, a counter electrode, and a reference electrode. The working electrode includes a first array of electrically conductive biocompatible nanostructures that is configured to be an attachment site for the biological sample. The counter electrode includes a second array of electrically conductive biocompatible nanostructures that is configured to acquire the electrical response from the working electrode. The reference electrode includes a third array of electrically conductive biocompatible nanostructures that is configured to adjust a specific voltage around the working and the counter electrodes.

Abstract: A method for preventing cytokine storm by suppressing clonal expansion of hyperactivated lymphocytes in a COVID-19 infected patient. The method includes placing at least four electrodes on skin of the COVID-19 infected patient by putting at least two electrodes at two locations over chest in front of ribcage of the COVID-19 infected patient and putting at least two other electrodes at two locations adjacent to lung tissue of the COVID-19 infected patient and suppressing mitosis of hyperactivated proliferative lymphocytes cells within the lung tissue of the COVID-19 infected patient by electrically stimulating the hyperactivated proliferative lymphocytes. Electrically stimulating the hyperactivated proliferative lymphocytes includes generating an alternating electric field (AEF) within the lung tissue by applying an AC voltage to the at least four electrodes and periodically changing a direction of the generated AEF in a plurality of directions within the lung tissue.

Abstract: A method for detecting sentinel lymph nodes during surgery. The method includes injecting a crystalloid solution into a region, measuring a plurality of electrical parameters utilizing a sensor, and detecting a sentinel lymph node among a plurality of lymph nodes based on the plurality of electrical parameters. The region is associated with a tumor in a patient's body. Measuring the plurality of electrical parameters includes measuring each respective electrical parameter of a respective lymph node of the plurality of lymph nodes. The plurality of lymph nodes are associated with the tumor. The sentinel lymph node is located at a shortest distance from the tumor among the plurality of lymph nodes.

Abstract: A method for detecting cancerous status of a suspected lymph node (LN) to be cancerous. The method includes measuring fatty acid oxidation (FAO) in the suspected LN by measuring a charge transfer resistance (RCT) associated with the suspected LN, and detecting, utilizing one or more processors, a cancerous status of the suspected LN. Detecting the cancerous status of the suspected LN includes detecting the suspected LN is cancer involved if the measured RCT is less than a reference RCT value, or detecting the suspected LN is healthy if the measured RCT is more than the reference RCT value.

Abstract: A system for destroying a cancerous tumor. The system includes an electrical probe, an impedance analyzer device configured to be connected to the electrical probe, a DC voltage generator configured to be connected to the electrical probe, and a processing unit connected to the impedance analyzer device and the DC voltage generator. The electrical probe includes a first electrode including a first electrically conductive needle, a second electrode including a second electrically conductive needle with a nanoporous surface placed inside the first electrode, a first electrically insulating layer placed around the first electrode except a first distal end portion of the first electrode, and a second electrically insulating layer placed between the first electrode and the second electrode. The processing unit configured to perform destroying the cancerous tumor by executing processor-readable instructions utilizing the impedance analyzer device and the DC voltage generator.

Abstract: A method for real-time and in-vivo detecting cancerous status of a suspected mass to in a living body. The method includes putting two electrodes of an electrical probe in contact with the suspected mass, recording an electrical impedance spectroscopy (EIS) from the suspected mass utilizing an impedance analyzer device connected to the electrical probe by plotting an impedance phase diagram respective to a swept range of frequencies while applying an alternating current (AC) voltage between the two electrodes, calculating an impedance phase slope (IPS) of the plotted impedance phase diagram in a frequency range between 100 kHz and 500 kHz, and detecting cancerous status of the suspected mass based on the calculated IPS. Detecting cancerous status of the suspected mass based on the calculated IPS includes detecting the suspected mass is a cancerous mass or a precancerous mass if the calculated IPS is less than a reference IPS.

Abstract: A method for destroying a cancerous tumor. The method includes putting two electrodes of an electrical probe in contact with a portion of the cancerous tumor, plotting an impedance phase diagram by measuring a set of electrical impedance phase values from the portion of the cancerous tumor at end of a respective set of pre-determined time steps, destroying cancer cells of the portion of the cancerous tumor within each time step of the respective set of pre-determined time steps by electrolyzing peripheral medium surrounding the cancer cells of the portion of the cancerous tumor by applying a direct current (DC) voltage between the two electrodes, and stopping destroying of the cancer cells responsive to a complete destruction of the portion of the cancerous tumor, where the complete destruction includes obtaining a positive slope of the impedance phase diagram (IPS).